Body

Hydrogels provide scaffolding for growth of bone cells

PHILADELPHIA—Hyaluronic hydrogels developed by Carnegie Mellon University researchers may provide a suitable scaffolding to enable bone regeneration. The hydrogels, created by Newell Washburn, Krzysztof Matyjaszewski and Jeffrey Hollinger, have proven to encourage the growth of preosteoblast cells, cells that aid the growth and development of bone. Doctoral student Sidi Bencherif will present this research, Sunday, Aug. 17 at the 236th national meeting of the American Chemical Society in Philadelphia.

Experiments could lead to new treatments for neuroblastoma

GALVESTON, Texas — Neuroblastoma is one of the most devastating diagnoses a child can receive. The cancer's victims average 2 years old when the disease is detected, most often by a parent feeling a lump in a child's abdomen. By then, the disease has often reached an advanced stage, and advanced neuroblastoma kills more than 50 percent of the children in whom it develops, despite aggressive treatment with surgery, chemotherapy and radiation.

Potatoes may hold key to Alzheimer's treatment

A virus that commonly infects potatoes bears a striking resemblance to one of the key proteins implicated in Alzheimer's disease (AD), and researchers have used that to develop antibodies that may slow or prevent the onset of AD.

Sweets make young horses harder to train in Montana State study

BOZEMAN, Mont. -- Young horses may be easier to train if they temporarily lay off the sweets, says a Montana State University study where two-year-olds wore pedometers, wrist watches and Ace bandages.

A commercial mixture of corn, oats, barley and molasses -- sometimes called "sweet grain" or "sweet feed" -- gives horses the glossy coat and lively spirit that makes them attractive to prospective buyers, said Jan Bowman, an animal nutritionist at MSU.

By amplifying cell death signals, scientists make precancerous cells self-destruct

When a cell begins to multiply in a dangerously abnormal way, a series of death signals trigger it to self-destruct before it turns cancerous. Now, in research to appear in the August 15 issue of Genes & Development, Rockefeller University scientists have figured out a way in mice to amplify the signals that tell these precancerous cells to die. The trick: Inactivating a protein that normally helps cells to avoid self-destruction.

Parents' expectations, styles can harm college students' self-esteem

Mom and Dad are going to flip out over my 3.3 GPA and failure to land a top internship.

Such anxieties, common among college students, can harm self-esteem and make it more difficult to adjust to school. But a new University of Central Florida study has found that students' anxieties often are based on exaggerated perceptions of what their parents expect.

True properties of carbon nanotubes measured

EVANSTON, Ill. --- For more than 15 years, carbon nanotubes (CNTs) have been the flagship material of nanotechnology. Researchers have conceived applications for nanotubes ranging from microelectronic devices to cancer therapy. Their atomic structure should, in theory, give them mechanical and electrical properties far superior to most common materials.

Caltech engineers build mini drug-producing biofactories in yeast

PASADENA, Calif.-- Researchers at the California Institute of Technology have developed a novel way to churn out large quantities of drugs, including antiplaque toothpaste additives, antibiotics, nicotine, and even morphine, using mini biofactories--in yeast.

A paper describing the research, now available online, will be featured as the cover article of the September issue of Nature Chemical Biology.

New mushroom study shows the power of energy density

SAN JOSE, Calif. (August 14, 2008) – Preliminary research, led by Dr. Lawrence Cheskin, MD, Director of John Hopkins Weight Management Center, suggests increasing intake of low-energy density foods, specifically mushrooms, in place of high-energy-density foods, like lean ground beef, is a strategy for preventing or treating obesity. This is good news for the more than one-third of U.S. adults age 20 and older who are obese, according to the Center for Disease Control. Obesity is a risk factor for cardiovascular disease, certain types of cancer, and type 2 diabetes.

Personalized immunotherapy to fight HIV/AIDS

Montreal, August 13, 2008 – For a long time, the main obstacle to creating an AIDS vaccine has been the high genetic variability of the HIV virus. Dr. Jean-Pierre Routy and his team from the Research Institute of the McGill University Health Centre (MUHC), in collaboration with Dr. Rafick Sékaly from the Université de Montréal, have overcome this difficulty by designing a personalized immunotherapy for HIV-infected patients. The team's findings were presented on August 5 at the XVII International AIDS Conference in Mexico City.

Cancer signatures uncovered

A new systematic analysis of the relationship between the neoplastic and developmental transcriptome provides an outline of trends in cancer gene expression. The research, published recently in BioMed Central's open access journal Genome Biology, describes how cancers can be divided into three groups distinguished by disparate developmental signatures.

'Virtual archaeologist' reconnects fragments of an ancient civilization

For several decades, archaeologists in Greece have been painstakingly attempting to reconstruct wall paintings that hold valuable clues to the ancient culture of Thera, an island civilization that was buried under volcanic ash more than 3,500 years ago.

This Herculean task -- more than a century of further work at the current rate -- soon may get much easier, thanks to an automated system developed by a team of Princeton University computer scientists working in collaboration with archaeologists in Greece.

Smithsonian scientists discover new bird species

Scientists at the Smithsonian Institution have discovered a new species of bird in Gabon, Africa, that was, until now, unknown to the scientific community. Their findings were published in the international science journal Zootaxa today, Aug. 15.

Hope for patients with COPD

For the first time, a drug therapy appears to reduce lung function loss in patients with moderate to severe chronic obstructive pulmonary disease (COPD), according to the results of a randomized, double-blind, placebo-controlled trial in 42 countries.

Asthma in boys may be just a phase, but for girls it may be there to stay

Boys may be more apt than girls to have childhood asthma, but, when compared to girls, they are also more likely to grow out of it in adolescence and have a decreased incidence of asthma in the post-pubertal years. This indicates that there may be a buried mechanism in asthma development, according to a prospective study that analyzed airway responsiveness (AR) in more than 1,000 children with mild to moderate asthma over a period of about nine years.