Body

Mutants with heterozygote disadvantage can prevent spread of transgenic animals

IBD patients face increased skin cancer risk

Certain patients with inflammatory bowel disease (IBD) may have an increased risk of skin cancer, which is intensified by the use of immunosuppressant medications , according to two new studies in Gastroenterology, the official journal of the American Gastroenterological Association. Immunosuppressants are commonly used in the treatment of IBD.

Neiker-Tecnalia report that noise pollution reduces the presence of songbirds in cities

A study by the University of the Americas (Universidad de la Américas Puebla) in Mexico and the Basque Institute for Agricultural Research and Development, Neiker-Tecnalia, highlights the fact that noise pollution has negative effects on songbirds in cities. The field work, carried out in urban parks in the Metropolitan Area of Puebla-Cholula (Mexico), reveals that the green zones most affected by noise have less bird species. Among the birds better adapted to urban conditions are various species of finches, sparrows and thrushes.

A better way to count molecules discovered

Researchers at the Swedish medical university Karolinska Institutet have developed a new method for counting molecules. Quantifying the amounts of different kinds of RNA and DNA molecules is a fundamental task in molecular biology as these molecules store and transfer the genetic information in cells. Thus, improved measurement techniques are crucial for understanding both normal and cancer cells.

System to reuse with health guarantees, sludge from wastewater

Calcinor GROUP, Neiker-Tecnalia and Gaiker-IK4, develop a system for reuse, with health guarantees, sludge from wastewater. Apply lime to sanitize sludge from sewage treatment plants and permit their use in agriculture with full guarantee for food security.

Tweaking a gene makes muscles twice as strong

La Jolla ---- An international team of scientists has created super-strong, high-endurance mice and worms by suppressing a natural muscle-growth inhibitor, suggesting treatments for age-related or genetics-related muscle degeneration are within reach.

The project was a collaboration between researchers at the Salk Institute for Biological Studies, and two Swiss institutions, Ecole Polytechnique Federale de Lausanne (EPFL) and the University of Lausanne.

Scripps Research team finds a weak spot on deadly ebolavirus

LA JOLLA, CA – November 20, 2011 – Scientists from The Scripps Research Institute and the US Army's Medical Research Institute of Infectious Diseases have isolated and analyzed an antibody that neutralizes Sudan virus, a major species of ebolavirus and one of the most dangerous human pathogens.

"We suspect that we've found a key spot for neutralizing ebolaviruses," said Scripps Research Associate Professor Erica Ollmann Saphire, who led the study with US Army virologist John M. Dye.

New Global Child Health curriculum announced in Canada

OTTAWA -- Globalization has led to significant changes in the health care of children worldwide, yet medical education in the developed world has remained domestically focused. Canadian pediatricians are caring for growing numbers of new immigrants, refugees and international adoptees, so their formal training should reflect these changes. Now medical trainees in Canada don't have to go abroad to improve cultural competency and expand their global health education.

Targeted antibacterial proteins may offer antibiotic alternative

SOUTH SAN FRANCISCO, CA -- A novel antibacterial protein targeted against E. coli O157:H7 may offer a way to prevent or treat serious food-borne bacterial infections, as demonstrated in a study published in the December issue of Antimicrobial Agents and Chemotherapy. Results in an animal model of E. coli infection showed that the orally administered protein, developed by AvidBiotics, Inc., could prevent or treat E. coli O157:H7-induced diarrhea and intestinal inflammation when administered either on a preventative basis or after the onset of diarrhea.

Molecular barcodes - identification of 16 new species of Caenorhabditis

Caenorhabditis are usually thought of as soil nematodes, happily living in compost heaps. The famous (scientifically speaking) Caenorhabditis elegans has provided a wealth of information about developmental processes and cell death. These tiny worms have been at the forefront of three Nobel prizes and have even been sent into space! However all other known Caenorhabditis species are as distantly related to C. elegans as mouse is to man.

U-M researchers find genetic rearrangements driving 5 to 7 percent of breast cancers

ANN ARBOR, Mich. — Researchers at the University of Michigan Comprehensive Cancer Center have discovered two cancer-spurring gene rearrangements that may trigger 5 to 7 percent of all breast cancers.

These types of genetic recombinations have previously been linked to blood cancers and rare soft-tissue tumors, but are beginning to be discovered in common solid tumors, including a large subset of prostate cancers and some lung cancers.

Study finds sex a significant predictor of happiness among married seniors

The more often older married individuals engage in sexual activity, the more likely they are to be happy with both their lives and marriages, according to new research presented in Boston at The Gerontological Society of America's (GSA) 64th Annual Scientific Meeting.

Recipient's immune system governs stem cell regeneration

A new study in Nature Medicine describes how different types of immune system T-cells alternately discourage and encourage stem cells to regrow bone and tissue, bringing into sharp focus the importance of the transplant recipient's immune system in stem cell regeneration.

The study, conducted at the Center for Craniofacial Molecular Biology at the Ostrow School of Dentistry of USC, examined how mice with genetic bone defects responded to infusions of bone marrow mesenchymal stem cells, or BMMSC.

Discovery of new muscle repair gene

An international team of researchers from Leeds, London and Berlin has discovered more about the function of muscle stem cells, thanks to next-generation DNA sequencing techniques.

The work, which was co-led from the University of Leeds' School of Medicine and the Charité, Berlin, is published this week in the journal Nature Genetics.

Genome sequence sheds new light on how plants evolved nitrogen-fixing symbioses

The genome of Medicago, a close relative of alfalfa and a long-established model for the study of legume biology, has been sequenced by an international team of scientists, capturing around 94 per cent of its genes.

The research gives new insights into the evolution of the Papilionoid subfamily of legumes, which includes peas, soybean and all legumes grown as crops.