Body

Plant seeds protect their genetic material against dehydration

Instant nanodots grow on silicon to form sensing array

Scientists have shown that it is now possible to simultaneously create highly reproductive three-dimensional silicon oxide nanodots on micrometric scale silicon films in only a few seconds. Xavier Landreau and his colleagues at the University of Limoges, France, demonstrated in their paper to be published in EPJD¹ that they were able to create a square array of such nanodots, using regularly spaced nanoindents on the deposition layer, that could ultimately find applications as biosensors for genomics or bio-diagnostics.

Scalable amounts of liver and pancreas precursor cells created using new stem cell production method

Scientists in Canada have overcome a key research hurdle to developing regenerative treatments for diabetes and liver disease with a technique to produce medically useful amounts of endoderm cells from human pluripotent stem cells. The research, published in Biotechnology and Bioengineering, can be transferred to other areas of stem cell research helping scientists to navigate the route to clinical use known as the 'valley of death'.

A natural dye obtained from lichens may combat Alzheimer's disease

A red dye derived from lichens that has been used for centuries to color fabrics and food appears to reduce the abundance of small toxic protein aggregates in Alzheimer's disease. The dye, a compound called orcein, and a related substance, called O4, bind preferentially to small amyloid aggregates that are considered to be toxic and cause neuronal dysfunction and memory impairment in Alzheimer's disease. O4 binding to small aggregates promotes their conversion into large, mature plaques which researchers assume to be largely non-toxic for neuronal cells.

Probiotics reduce infections for patients in intensive care

Traumatic brain injury is associated with a profound suppression of the patient's ability to fight infection. At the same time the patient also often suffers hyper-inflammation, due to the brain releasing glucocorticoids in response to the injury. New research published in BioMed Central's open access journal Critical Care shows that including probiotics with nutrients, supplied via the patient's feeding tube, increased interferon levels, reduced the number of infections, and even reduced the amount of time patients spent in intensive care.

Vegetables, fruits, grains reduce stroke risk in women

Swedish women who ate an antioxidant-rich diet had fewer strokes regardless of whether they had a previous history of cardiovascular disease, in a study reported in Stroke: Journal of the American Heart Association.

"Eating antioxidant-rich foods may reduce your risk of stroke by inhibiting oxidative stress and inflammation," said Susanne Rautiainen, M.Sc., the study's first author and Ph.D. student at the Karolinska Institutet in Sweden. "This means people should eat more foods such as fruits and vegetables that contribute to total antioxidant capacity."

Tumor-targeting compound points the way to new personalized cancer treatments

NEW YORK -- One major obstacle in the fight against cancer is that anticancer drugs often affect normal cells in addition to tumor cells, resulting in significant side effects. Yet research into development of less harmful treatments geared toward the targeting of specific cancer-causing mechanisms is hampered by lack of knowledge of the molecular pathways that drive cancers in individual patients.

Lower antioxidant level might explain higher skin-cancer rate in males

COLUMBUS, Ohio – Men are three times more likely than women to develop a common form of skin cancer but medical science doesn't know why. A new study may provide part of the answer.

Researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) have found that male mice had lower levels of an important skin antioxidant than female mice and higher levels of certain cancer-linked inflammatory cells.

Outsiders on the front lines

Dec. 1, 2011 --- Women have a long history of protesting war, but anti-war protest by women who've served as soldiers is a relatively new phenomenon. While there's a growing rate of women serving in western militaries (with some women in combat roles), little is known about how military service shapes the political attitudes of women and connects them with larger antiwar movements.

Some atheist scientists with children embrace religious traditions, according to new Rice research

Some atheist scientists with children embrace religious traditions for social and personal reasons, according to research from Rice University and the University at Buffalo -- The State University of New York (SUNY).

The study also found that some atheist scientists want their children to know about different religions so their children can make informed decisions about their own religious preferences.

Massachusetts General study finds amplification of multiple cell-growth genes in some brain tumors

A small percentage of the deadly brain tumors called glioblastomas, which usually resist treatment with drugs targeting mutations in cell-growth genes, appears to contain extra copies of two or three of these genes at the same time. The surprising discovery by a Massachusetts General Hospital (MGH)-based research team has major implications for the understanding of tumor biology – including the evolution of tumor cell populations – and for targeted cancer therapies.

New insights come from tracing cells that scar lungs

DURHAM, N.C. -- Tracking individual cells within the lung as they move around and multiply has given Duke University researchers new insights into the causes of Idiopathic Pulmonary Fibrosis (IPF) a disease which can only be treated now by lung transplantation.

IPF fills the delicate gas exchange region of the lung with scar tissue, progressively restricting breathing. The Duke University Medical Center researchers have discovered that some commonly held ideas about the origins of the scar-forming (fibrotic) cells are oversimplified, if not wrong.

MU researchers recommend exercise for breast cancer survivors, lymphedema patients

COLUMBIA, Mo. – Lymphedema, a chronic swelling condition common in breast cancer survivors, affects three million people in the U.S. In the past, most people believed that exercise might induce or worsen lymphedema. After reviewing the literature, University of Missouri researchers say the benefits of exercise outweigh the risks for breast cancer survivors and patients with lymphedema.

Jane Armer, professor in the Sinclair School of Nursing, says patients at risk for lymphedema can exercise if they closely monitor their activities.

Transplant candidates seek 'best quality' livers despite having to remain on waiting list

New research reveals that liver transplantation candidates want to be involved in decisions regarding quality of the donor organ, and many are reluctant to accept organs with a higher risk of failure. In fact, more than 42% of patients would choose to remain on the waiting list rather than accept a "lower quality" liver according to the study appearing in the December issue of Liver Transplantation, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

Green tea flavonoid may prevent reinfection with hepatitis C virus following liver transplantation

German researchers have determined that epigallocatechin-3-gallate (EGCG)—a flavonoid found in green tea—inhibits the hepatitis C virus (HCV) from entering liver cells. Study findings available in the December issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases, suggest that EGCG may offer an antiviral strategy to prevent HCV reinfection following liver transplantation.