Body

Cholesterol-lowering medication accelerates depletion of plaque in arteries

In a new study, NYU Langone Medical Center researchers have discovered how cholesterol-lowering drugs called statins promote the breakdown of plaque in the arteries. The study was published online by the journal PLoS One on December 6, 2011.

Nanoparticles help Mayo Clinic researcher deliver steroids to retina

ROCHESTER, Minn. -- Hitching a ride into the retina on nanoparticles called dendrimers offers a new way to treat age-related macular degeneration and retinitis pigmentosa. A study by investigators at Mayo Clinic, Wayne State University and Johns Hopkins Medicine shows that steroids attached to the dendrimers target the damage-causing cells associated with neuroinflammation, leaving the rest of the eye unaffected and preserving vision. The findings appear in the journal Biomaterials.

Insulin signaling is distorted in pancreases of Type 2 diabetics

SAN ANTONIO (Dec. 13, 2011) — Insulin signaling is altered in the pancreas, a new study shows for the first time in humans. The errant signals disrupt both the number and quality of beta cells — the cells that produce insulin.

Major cause of chronic kidney disease-related inflammation is identified

Irvine, Calif., Dec. 13, 2011 — UC Irvine researchers have uncovered an important source of inflammation seen in people with chronic kidney disease, which is increasingly common due to the epidemic of obesity-related diabetes and hypertension.

In third-degree burn treatment, hydrogel helps grow new, scar-free skin

Johns Hopkins researchers have developed a jelly-like material and wound treatment method that, in early experiments on skin damaged by severe burns, appeared to regenerate healthy, scar-free tissue.

All it takes is a smile (for some guys)

Does she or doesn't she . . .? Sexual cues are ambiguous, and confounding. We—especially men—often read them wrong. A new study hypothesizes that the men who get it wrong might be the ones that evolution has favored. "There are tons of studies showing that men think women are interested when they're not," says Williams College psychologist Carin Perilloux, who conducted the research with Judith A. Easton and David M. Buss of University of Texas at Austin.

Life after cigarettes

Life without cigarettes is not all doom and gloom. In fact, successful quitters are more satisfied with their lives and feel healthier, both one year and three years afterwards, than those who continue to smoke. That's according to new research by Dr. Megan Piper, from the University of Wisconsin School of Medicine and Public Health in the US, and her team. Their work, which looks at whether quitting smoking can improve psychological well-being, is published online in Springer's journal Annals of Behavioral Medicine.

Inspired by insect cuticle, Wyss Institute develops material that's tough and strong

Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have developed a new material that replicates the exceptional strength, toughness, and versatility of one of nature's more extraordinary substances—insect cuticle. Also low-cost, biodegradable, and biocompatible, the new material, called "Shrilk," could one day replace plastics in consumer products and be used safely in a variety of medical applications.

HIV drug reduces graft-versus-host disease in stem cell transplant patients, Penn study shows

(SAN DIEGO) -- An HIV drug that redirects immune cell traffic appears to significantly reduce the dangerous complication graft-versus-host disease (GvHD) in blood cancer patients following allogeneic stem cell transplantation (ASCT), according to new research from the Perelman School of Medicine at the University of Pennsylvania that will be presented today at the 53rd American Society of Hematology Annual Meeting. Standard GvHD treatments suppress the immune system, reducing – but not eliminating – the risk of developing the common problem.

New pink fancy-leaved caladium debuts

WIMAUMA, FL—Beautiful ornamental caladiums, valued for their bright, long-lasting, and colorful leaves, are prized throughout the world as container and landscape plants. In Florida, where more than 95% of the world's caladium tubers are produced, researchers are continuously working to develop new varieties to satisfy consumer demand. Plant scientists Zhanao Deng, Brent K. Harbaugh and Natalia A. Peres from the University of Florida's Institute of Food and Agricultural Sciences recently introduced a new caladium (HortScience) that they say should be an all-around winner.

Unexpected signaling role for foul-smelling hydrogen sulfide in cell response to protein misfolding

Cold Spring Harbor, NY -- Something rotten never smelled so sweet.

This is what members of a team of scientists at Cold Spring Harbor Laboratory (CSHL) are telling one another as they discuss a new finding they did not expect to make. They have discovered that hydrogen sulfide (H2S) – the flammable, highly toxic gas that we usually associate with the smell of rotten eggs in landfills and sewers – plays an important role in the regulation of a signaling pathway implicated in biological malfunctions linked to Alzheimer's and Parkinson's diseases, among others.

Rutgers study: When it comes to use of dental services, not all NJ youngsters are equal

When it comes to receiving dental care, New Jersey has its share of underserved children, according to a Rutgers study.

In 2009, more than one-fifth of the state's children between 3 and 18 received no dental care within the previous year. While an improvement over 2001, when almost one-third of the state's children received no care, the study found that foreign-born children and those without health insurance were still likely to forgo visits to the dentist.

Visualization of DNA synthesis in vivo

Interactions of biological macromolecules are the central bases of living systems. Biological macromolecules are synthesized in living cells by linking many small molecules together. Naturally occurring macromolecules include genetic materials (DNA) and proteins. A detailed understanding of the synthesis of these macromolecules in whole animals is a basic requirement for understanding biological systems, and for the development of new therapeutic strategies.

A good nose: RUB-Researchers decipher interaction of fragrances and olfactory receptors

Banana, mango or apricot - telling these smells apart is no problem for the human nose. How the olfactory organ distinguishes such similar smells has been uncovered by an interdisciplinary team of researchers at the RUB. The scientists were the first to shed light on the dynamics of the three-dimensional structure of the binding site of an olfactory receptor. In so doing, they also found a characteristic pattern of hydrogen bonds between odorant and receptor, which accounts for the specificity of the olfactory sensors.

Scientists forecast crops that adapt to changing weather

Crops that can cope with sudden fluctuations in the weather could be developed, thanks to fresh discoveries about the survival mechanisms of plants.

Scientists studying how tiny algae renew old or damaged cell proteins say their findings could be useful in developing crops suited to climates in which weather changes quickly.

Researchers found that the speed at which protein renewal takes place dictates how quickly they can adapt to environmental changes, such as a sudden frost or drought.