Body

Kidney stenting lowers blood pressure in patients with severe hypertension

Patients with uncontrolled renovascular hypertension saw a significant improvement in their blood pressure with renal artery stent deployment. The multicenter HERCULES trial, evaluating the safety and effectiveness of the RX Herculink Elite Stent, found that patients with higher blood pressure levels at baseline had the most dramatic reduction in blood pressure following intervention. Trial details appear in Catheterization and Cardiovascular Interventions, a journal published by Wiley on behalf of the Society for Cardiovascular Angiography and Interventions (SCAI).

Millipede family added to Australian fauna

An entire group of millipedes previously unknown in Australia has been discovered by a specialist – on museum shelves. Hundreds of tiny specimens of the widespread tropical family Pyrgodesmidae have been found among bulk samples in two museums, showing that native pyrgodesmids are not only widespread in Australia's tropical and subtropical forests, but are also abundant and diverse.

What babies eat after birth likely determines lifetime risk of obesity, rat study suggests

Rats born to mothers fed high-fat diets but who get normal levels of fat in their diets right after birth avoid obesity and its related disorders as adults, according to new Johns Hopkins research.

Meanwhile, rat babies exposed to a normal-fat diet in the womb but nursed by rat mothers on high-fat diets become obese by the time they are weaned.

Many US schools are unprepared for another pandemic

Washington, DC, August 30, 2012 – Less than half of U.S. schools address pandemic preparedness in their school plan, and only 40 percent have updated their school plan since the 2009 H1N1 pandemic, according to a study published in the September issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

Cancer 'turns off' important immune cells, complicating experimental vaccine therapies

Bethesda, MD—A research report published in the September 2012 issue of the Journal of Leukocyte Biology offers a possible explanation of why some cancer vaccines are not as effective as hoped, while at the same time identifies a new therapeutic strategy for treating autoimmune problems. In the report, scientists suggest that cancer, even in the very early stages, produces a negative immune response from dendritic cells, which prevent lymphocytes from working against the disease.

Bees that go 'Cuckoo' in others' nests

The biota of island archipelagos is of considerable interest to biologists. These isolated areas often act as 'evolutionary laboratories', spawning biological diversity rapidly and permitting many mechanisms to be observed and studied over relatively short periods of time. Such islands are often the places of new discoveries, including the documentation of new species.

Possible therapy for tamoxifen resistant breast cancer identified

  • The hormone estrogen stimulates the growth of breast cancers that are estrogen-receptor positive, the most common form of breast cancer.
  • The drug tamoxifen blocks this estrogen effect and prolongs the lives of, and helps to cure, patients with estrogen-sensitive breast cancer.
  • About 30 percent of these patients have tumors that are resistant to tamoxifen.
  • This study shows how these resistant tumors survive and grow, and it identifies an experimental agent that targets these breast cancers.
  • Protein impedes microcirculation of malaria-infected red blood cells

    CAMBRIDGE, MA -- When the parasite responsible for malaria infects human red blood cells, it launches a 48-hour remodeling of the host cells. During the first 24 hours of this cycle, a protein called RESA undertakes the first step of renovation: enhancing the stiffness of the cell membranes.

    That increased rigidity impairs red blood cells' ability to travel through the blood vessels, especially at fever temperatures, according to a new study from researchers at MIT, the Institut Pasteur and the Korea Advanced Institute of Science and Technology (KAIST).

    Malaria nearly eliminated in Sri Lanka despite decades of conflict

    Despite nearly three decades of conflict, Sri Lanka has succeeded in reducing malaria cases by 99.9 percent since 1999 and is on track to eliminate the disease entirely by 2014.

    According to a paper published today in the online, open-access journal PLOS ONE, researchers from Sri Lanka's Anti-Malaria Campaign and the UCSF Global Health Group examined national malaria data and interviewed staff of the country's malaria program to determine the factors behind Sri Lanka's success in controlling malaria, despite a 26-year civil war that ended in 2009.

    New DNA-method tracks fish and whales in seawater

    Danish researchers at University of Copenhagen lead the way for future monitoring of marine biodiversity and resources. By using DNA traces in seawater samples to keep track of fish and whales in the oceans. A half litre of seawater can contain evidence of local fish and whale faunas and combat traditional fishing methods. Their results are now published in the international scientific journal PLOS ONE.

    State tax incentives do not appear to increase the rate of living organ donation

    The policies that several states have adopted giving tax deductions or credits to living organ donors do not appear to have increased donation rates. Authors of the study, appearing in the August issue of the American Journal of Transplantation, found little difference in the annual number of living organ donations per 100,000 population between the 15 states that had enacted some sort of tax benefit as of 2009 and states having no such policy at that time.

    Early menopause: A genetic mouse model of human primary ovarian insufficiency

    Scientists have established a genetic mouse model for primary ovarian insufficiency (POI), a human condition in which women experience irregular menstrual cycles and reduced fertility, and early exposure to estrogen deficiency.

    First validated method for analyzing flavanols and procyanidins in cocoa products could help scientists and the industry in stan

    Mars, Incorporated, working in partnership with AOAC International, has successfully completed a multi-laboratory, first-of-its-kind validation of a method for analyzing flavanols and procyanidins in cocoa-based products. The study, just published in the latest edition of the Journal of AOAC International, details the results of a comprehensive evaluation of this method by 12 international laboratories, which included academic, industrial and commercial institutions.

    Keep your distance! Why cells and organelles don't get stuck

    Biomembranes enclose biological cells like a skin. They also surround organelles that carry out important functions in metabolism and cell division. Scientists have long known in principle how biomembranes are built up, and also that water molecules play a role in maintaining the optimal distance between neighboring membranes—otherwise they could not fulfill their vital functions.

    Scientists call policy-makers to be scale-aware

    To be successful, nature conservation measures must account for the complexity of the human impact and how nature responds to them, at different spatial and temporal scales. "Scale-sensitive research" emerges as a new, interdisciplinary field in nature conservation where researchers adjust concepts, analyses, and tools to the scale in which these might be used. Policy-makers, on their side, must ensure that the decisions they take resolve ecological problems at the relevant administrative and spatial scales.