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National study provides insights into childhood head injuries

(SACRAMENTO, Calif.) -- This week's issue of the New England Journal of Medicine features an article that highlights an unprecedented analysis of the nation's childhood head injuries. The study, authored by physicians at UC Davis School of Medicine and Washington University School of Medicine, analyzed more than 43,000 children who were evaluated for head trauma at 25 emergency departments around the United States.

Cancer-killing virus plus chemotherapy drug might treat recurrent ovarian cancer

COLUMBUS, Ohio - In six out of 10 cases, ovarian cancer is diagnosed when the disease is advanced and five-year survival is only 27 percent. A new study suggests that a cancer-killing virus combined with a chemotherapy drug might safely and effectively treat advanced or recurrent forms of the disease.

Sleep disorders found to be highly prevalent in firefighters

BOSTON, MA - Sleep disorders are independent risk factors for heart attacks and motor vehicle crashes, which are the two leading causes of death for firefighters in the United States. In a national sample of almost 7,000 firefighters, researchers at Brigham and Women's Hospital (BWH) examined the prevalence of common sleep disorders and their association with adverse health and safety outcomes and found that sleep disorders are highly prevalent, and associated with substantially increased risk of motor vehicle crashes and cardio-metabolic diseases among firefighters.

Moms with rheumatoid arthritis more likely to give birth prematurely

Researchers from Denmark and the U.S. report that babies of women with rheumatoid arthritis (RA) or pre-clinical RA--the period prior to symptoms--are 1.5 times more likely to be born prematurely in Denmark. Findings published in Arthritis & Rheumatology, a journal of the American College of Rheumatology (ACR), indicate that body measurements of the baby at birth were only slightly lower in children exposed to maternal or preclinical RA compared to those with no exposure to the disease. Paternal RA was not found to impact fetal growth or preterm birth risk.

Did men evolve navigation skills to find mates?

SALT LAKE CITY, Nov. 13, 2014 - A University of Utah study of two African tribes found evidence that men evolved better navigation ability than women because men with better spatial skills - the ability to mentally manipulate objects - can roam farther and have children with more mates.

Pre-pregnancy body weight affects early development of human embryos

New research indicates that the embryos of women who are overweight or obese at the time they conceive display distinct differences in early development compared to embryos from women of a healthy weight.

The results of the study, published today in the journal Human Reproduction, provide strong evidence for a direct link between what mothers eat and the ability of their fertilised eggs to divide and grow. The researchers claim this could potentially have long-term health implications for any children born from these embryos.

Prostate cancer researchers develop personalized genetic test to predict recurrence risk

(TORONTO, Canada - Nov. 13, 2014) - Prostate cancer researchers have developed a genetic test to identify which men are at highest risk for their prostate cancer to come back after localized treatment with surgery or radiotherapy.

Do homing pigeons navigate with gyroscope in brain?

Human communication has long been associated with an unlikely companion, the homing pigeon; but how these pigeons find their way home is still largely a mystery. 'There is widespread agreement that pigeons are able to determine and maintain flight (compass) directions based on solar and magnetic cues,' says Hans-Peter Lipp from the University of Zurich, Switzerland, and Kwazulu-Natal University, South Africa. However, another piece of the puzzle - how the bird determines its position, known as the map sense - was unclear.

Climate change puts coastal crabs in survival mode, study finds

SAN FRANCISCO, Nov. 12, 2014 -- Porcelain crabs can adapt to a warming climate but will not have energy for much else beyond basic survival, according to new research published today from San Francisco State University.

The findings have grim long-term implications for intertidal zone crabs as well as the myriad species that depend on them, and could be an indicator of how other intertidal organisms may respond to a rapidly changing climate.

Errors in single gene may protect against heart disease

Rare mutations that shut down a single gene are linked to lower cholesterol levels and a 50 percent reduction in the risk of heart attack, according to new research from Washington University School of Medicine in St. Louis, the Broad Institute at Massachusetts Institute of Technology and Harvard, and other institutions.

The gene, called NPC1L1, is of interest because it is the target of the drug ezetimibe, often prescribed to lower cholesterol.

The study appears Nov. 12 in The New England Journal of Medicine.

Experts address challenges of delivering critical care in resource-poor countries

Philadelphia, PA, November 12, 2014 - Critical care is defined by life-threatening conditions, which require close evaluation, monitoring, and treatment by appropriately trained health professionals. Cardiovascular care bears these same requirements. In fact, cardiovascular disease will soon surpass even human immunodeficiency virus (HIV) as the leading cause of mortality in Sub-Saharan Africa. In the latest issue of Global Heart, researchers discuss the challenges of delivering critical care in resource-limited countries.

Linking diet to human and environmental health

(Santa Barbara, California) -- The world is gaining weight and becoming less healthy, and global dietary choices are harming the environment.

Study: Vitamin B may not reduce risk of memory loss

MINNEAPOLIS - Taking vitamin B12 and folic acid supplements may not reduce the risk of memory and thinking problems after all, according to a new study published in the November 12, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study is one of the largest to date to test long-term use of supplements and thinking and memory skills.

The study involved people with high blood levels of homocysteine, an amino acid. High levels of homocysteine have been linked to memory loss and Alzheimer's disease.

Quarter of patients have subsequent surgery after breast conservation surgery

Nearly a quarter of all patients who underwent initial breast conservation surgery (BCS) for breast cancer had a subsequent surgical intervention, according to a report published online by JAMA Surgery.

Completely removing breast cancer is seen as the best way to reduce recurrence and improve survival. A lack of consensus on an adequate margin width has led to variable rates of reexcision and, as a result, patients undergo repeat or additional surgeries, according to background information provided in the study.

New scientific review reveals huge gaps in understanding preterm birth

SEATTLE - Preterm birth is now the leading cause of death for children under 5 worldwide, and a new scientific paper reveals a startling lack of knowledge about what causes it and how to prevent it.

Published in the November issue of Science Translational Medicine, "Prevention of Preterm Birth: Harnessing Science to Address the Global Epidemic" shines a light on the urgent need for a larger, coordinated research effort to discover how to identify women at risk of preterm birth and develop prevention interventions.