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Environmental 'tipping points' key to predicting extinctions

Researchers from North Carolina State University have created a model that mimics how differently adapted populations may respond to rapid climate change. Their findings demonstrate that depending on a population's adaptive strategy, even tiny changes in climate variability can create a "tipping point" that sends the population into extinction.

Penn team's game theory analysis shows how evolution favors cooperation's collapse

Last year, University of Pennsylvania researchers Alexander J. Stewart and Joshua B. Plotkin published a mathematical explanation for why cooperation and generosity have evolved in nature. Using the classical game theory match-up known as the Prisoner's Dilemma, they found that generous strategies were the only ones that could persist and succeed in a multi-player, iterated version of the game over the long term.

Wireless electronic implants stop staph, then dissolve

MEDFORD/SOMERVILLE, Mass. (Nov. 24, 2014, 3 P.M.) -- Researchers at Tufts University, in collaboration with a team at the University of Illinois at Champaign-Urbana, have demonstrated a resorbable electronic implant that eliminated bacterial infection in mice by delivering heat to infected tissue when triggered by a remote wireless signal. The silk and magnesium devices then harmlessly dissolved in the test animals. The technique had previously been demonstrated only in vitro.

JAX research team identifies new mechanism for misfolded proteins in heart disease

A Jackson Laboratory research team has found that the misfolded proteins implicated in several cardiac diseases could be the result not of a mutated gene, but of mistranslations during the "editing" process of protein synthesis.

Toxin targets discovered

Research that provides a new understanding of how bacterial toxins target human cells is set to have major implications for the development of novel drugs and treatment strategies.

Cholesterol-dependent cytolysins (CDCs) are toxins produced by major bacterial pathogens, most notably Streptococcus pneumoniae and group A streptococci, which collectively kill millions of people each year.

The toxins were thought to work by interacting with cholesterol in target cell membranes, forming pores that bring about cell death.

UAlberta researchers stop 'vicious cycle of inflammation' that leads to tumor growth

(Edmonton) A team of researchers from the University of Alberta has discovered a new approach to fighting breast and thyroid cancers by targeting an enzyme they say is the culprit for the "vicious cycle" of tumour growth, spread and resistance to treatment.

Obese children burdened by more than weight

High blood pressure and nonalcoholic fatty liver disease (NAFLD) are two emerging health problems related to the epidemic of childhood obesity. In a recent study, researchers at University of California, San Diego School of Medicine sought to determine the prevalence of high blood pressure in children with NAFLD, which places them at risk for premature cardiovascular disease.

The study, published in the November 24 edition of PLOS ONE, found that children with NAFLD are at substantial risk for high blood pressure, which is commonly undiagnosed.

New bird species confirmed 15 years after first observation

PRINCETON, N.J.--A team led by researchers from Princeton University, Michigan State University and the Indonesian Institute of Sciences have confirmed the discovery of a new bird species more than 15 years after the elusive animal was first seen on the Indonesian island of Sulawesi.

Study shows mental health impact of breast size differences in teens

November 24, 2014 - Differences in breast size have a significant mental health impact in adolescent girls, affecting self-esteem, emotional well-being, and social functioning, reports the December issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

Shared medical appointments increase contact time between women considering breast reduction and their surgeon

November 24, 2014 - For women considering breast reduction surgery, initial evaluation at a shared medical appointment (SMA) provides excellent patient satisfaction in a more efficient clinic visit, reports a study in the December issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

Asteroid impacts on Earth make structurally bizarre diamonds

Scientists have argued for half a century about the existence of a form of diamond called lonsdaleite, which is associated with impacts by meteorites and asteroids. A group of scientists based mostly at Arizona State University now show that what has been called lonsdaleite is in fact a structurally disordered form of ordinary diamond.

Lionfish analysis reveals most vulnerable prey as invasion continues

CORVALLIS, Ore. - If you live in lionfish territory in the Atlantic Ocean, the last thing you want to be is a small fish with a long, skinny body, resting by yourself at night, near the bottom of the seafloor.

If so, your chances of being gobbled up by a lionfish increase by about 200 times.

Preconception care for diabetic women could potentially save $5.5 billion

Philadelphia, PA, November 24, 2014 - Pregnant women with diabetes are at an increased risk for many adverse birth outcomes. Preconception care (PCC) can significantly lower these risks by helping pregnant mothers with diabetes control their glucose levels, resulting in healthier babies and less money spent on complicated deliveries and lifelong medical complications.

Can stress management help save honeybees?

Honeybee populations are clearly under stress--from the parasitic Varroa mite, insecticides, and a host of other factors--but it's been difficult to pinpoint any one of them as the root cause of devastating and unprecedented losses in honeybee hives. Researchers writing in the Cell Press journal Trends in Parasitology on November 24th say that the problem likely stems from a complex and poorly understood interplay of stresses and their impact on bee immunity and health. It's a situation they suspect might be improved through stress management and better honeybee nutrition.

Selenium compounds boost immune system to fight against cancer

The immune system is designed to remove things not normally found in the body. Cells undergoing change, e.g. precursors of cancer cells, are therefore normally recognised and removed by the immune system. Unfortunately, the different cancer cells contain mechanisms that block the immune system's ability to recognise them, allowing them to freely continue cancer development.

Certain cancer cells overexpress immunostimulatory molecules in liquid form. Such over-stimulation has a negative impact on the immune system: