Body

PROVIDENCE, R.I. - Some infections after prostate biopsy due to drug-resistant Escherichia coli can be thwarted by simple rectal swab cultures prior to the procedure. The cultures test for antibiotic-resistant E. coli, and the findings are used to direct the selection of antimicrobial prophylaxis used for the procedure, according to Rhode Island Hospital researchers. The study was recently published in Urology.

AMHERST, Mass. - New three-dimensional (3D) numerical modeling that captures far more geometric complexity of an active fault segment in southern California than any other, suggests that the overall earthquake hazard for towns on the west side of the Coachella Valley such as Palm Springs and Palm Desert may be slightly lower than previously believed.

CLEVELAND: Researchers from Seidman Cancer Center at University Hospitals (UH) Case Medical Center and Case Western Reserve University School of Medicine presented new research findings this weekend at the 56th Annual Meeting of the American Society of Hematology (ASH) in San Francisco.

A genetic misfire called the 3q26.2 amplicon can cause real havoc. In fact, it is among the most frequent chromosomal aberrations seen in many cancers, including ovarian and breast cancers.

BLOOMINGTON, Ind. -- A new treatment for adult-onset diabetes and obesity developed by researchers at Indiana University and the German Research Center for Environmental Health has essentially cured lab animals of obesity, diabetes and associated lipid abnormalities through improved glucose sensitivity, reduced appetite and enhanced calorie burning.

Scientists from the Spanish National Cancer Research Centre (CNIO), led by Guillermo Montoya, have developed a method for producing biological crystals that has allowed scientists to observe --for the first time-- DNA double chain breaks. They have also developed a computer simulation that makes this process, which lasts in the order of millionths of a second, visible to the human eye. The study is published today by the journal Nature Structural & Molecular Biology.

Sexual behaviour of teenage girls does not appear to be impacted by the human papilloma virus (HPV) vaccine, according to Queen's researchers Drs. Leah Smith and Linda Lévesque.

There are concerns the vaccine, which guards against four types of the HPV shown to cause cervical cancer and anogenital warts, may give girls a false sense of security about contracting sexually transmitted infections (STIs) and lead them to engage in riskier sexual activity.

When cancer is diagnosed, the grade of its malignancy is a central concern for both patients and their physicians. This value is used to determine how intensively and how radically the cancer must be treated. Particularly in the case of prostate cancer, the disease can take widely varying courses in different patients. Therefore, cancer researchers have been looking for measurable, reliable biomarkers that give clues about the aggressiveness of a tumor in order to choose an appropriate therapy.

BOSTON and CAMBRIDGE -- The genetic tumult within cancerous tumors is more than matched by the disorder in one of the mechanisms for switching cells' genes on and off, scientists at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard report in a new study. Their findings, published online today in the journal Cancer Cell, indicate that the disarray in the on-off mechanism - known as methylation - is one of the defining characteristics of cancer and helps tumors adapt to changing circumstances. 

BOSTON -- Small cell lung cancer - a disease for which no new drugs have been approved for many years - has shown itself vulnerable to an agent that disables part of tumor cells' basic survival machinery, researchers at Dana-Farber Cancer Institute and the Massachusetts Institute of Technology reported. 

The same research team that developed the first laser based on a living cell has shown that use of fluorescent proteins in a solid form rather than in solution greatly increases the intensity of light produced, an accomplishment that takes advantage of natural protein structures surrounding the light-emitting portions of the protein molecules. The findings from investigators Seok Hyun Yun, PhD, of the Wellman Center for Photomedicine at Massachusetts General Hospital and Malte Gather, PhD, of the University of St. Andrews in the U.K.

CHARLOTTESVILLE, Va. -- The majority of streams in the Chesapeake Bay region are warming, and that increase appears to be driven largely by rising air temperatures. These findings are based on new U.S. Geological Survey research published in the journal Climatic Change.

Washington, DC (December 8, 2014) - Scrolling through the comments section on a news site is like seeing a verbal war before your eyes. Internet trolls flourish in an anonymous world, so much so that sites like Reuters and Popular Science have done away with the comment sections altogether. But there has to be a better way to let the audience engage in a civil manner.

A technique that can identify causes of cancer invisible to genetic sequencing has uncovered large sets of previously unknown pancreatic cancer genes. It is hoped that this study will boost research into a disease that is still poorly understood and for which five-year survival rates have stood at around 5 per cent for the past four decades.

Recently, the researchers had constructed several single molecules with dual hormone action. Now, for the first time, the researchers succeeded in designing a substance that combines three metabolically active hormone components (GLP-1, GIP and glucagon) and offers unmatched potency to fight metabolic diseases in pre-clinical trials.