Body

In the Northeast, forests with entirely native flora are not the norm

Two-thirds of all forest inventory plots in the Northeast and Midwestern United States contain at least one non-native plant species, a new U.S. Forest Service study found. The study across two dozen states from North Dakota to Maine can help land managers pinpoint areas on the landscape where invasive plants might take root.

Chemo, radiation followed by surgery improves survival in lung cancer patients

In one of the largest observational studies of its kind, researchers report that a combination of chemotherapy and radiation followed by surgery in patients with stage 3 non-small cell lung cancer improves survival.

Patients who had chemoradiation therapy followed by surgery had twice the five-year survival rate of those who had only chemoradiation, says Dr. Matthew Koshy, a radiation oncologist at the University of Illinois Hospital & Health Sciences System and lead author of the study.

Advancing emergency care for kids: Emergency physicians do it again

WASHINGTON —Most children with isolated skull fractures may not need to stay in the hospital, which finding has the potential to save the health care system millions of dollars a year ("Isolated Skull Fractures: Trends in Management in U.S. Pediatric Emergency Departments"). In addition, a new device more accurately estimates children's weights, leading to more precise drug dosing in the ER ("Evaluation of the Mercy TAPE: Performance Against the Standard for Pediatric Weight Estimation").

Targeted C. difficile screening at hospital admission could potentially ID most colonized patients

Washington, DC, April 30, 2013 – Testing patients with just three risk factors upon hospital admission has potential to identify nearly three out of four asymptomatic carriers of C. difficile, according to a new study published in the May issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

The many faces of the bacterial defense system

Even bacteria have a kind of "immune system" they use to defend themselves against unwanted intruders – in their case, viruses. Scientists at the Helmholtz Center for Infection Research (HZI) in Braunschweig, Germany, were now able to show that this defense system is much more diverse than previously thought and that it comes in multiple versions. Their goal is to use the various newly discovered versions of the CRISPR-Cas gene for the targeted manipulation of genetic information, particularly for medical purposes.

Decoded: Molecular messages that tell prostate and breast cancers to spread

ANN ARBOR—Cancer cells are wily, well-traveled adversaries, constantly side-stepping treatments to stop their spread. But for the first time, scientists at the University of Michigan have decoded the molecular chatter that ramps certain cancer cells into overdrive and can cause tumors to metastasize throughout the body.

Study finds possible alternative to bariatric weight loss surgery

CINCINNATI – An experimental procedure successfully tested in obese laboratory rats may provide a less-invasive alternative to bariatric weight-loss surgery, researchers report online in Endocrinology.

Scientists at Cincinnati Children's Hospital Medical Center used a catheter to re-direct the flow of bile from the bile duct into the small intestine, producing the same metabolic and weight-loss benefits as bariatric surgeries such as gastric by-pass. They named the procedure bile diversion, or BD.

UMass Amherst biologists propose a new research roadmap for connecting genes to ecology

AMHERST, Mass. – A team of researchers at the University of Massachusetts Amherst is proposing a new investigative roadmap for the field of evolutionary developmental biology, or "evo devo," to better understand how innovation at the genetic level can lead to ecological adaptations over time. Evo devo seeks to understand the specific genetic mechanisms underlying evolutionary change.

Identification of stem cells raises possibility of new therapies

WINSTON-SALEM, N.C., – April 30, 2013 – Many diseases – obesity, Type 2 diabetes, muscular dystrophy – are associated with fat accumulation in muscle. In essence, fat replacement causes the muscles to weaken and degenerate.

Scientists at Wake Forest Baptist Medical Center have discovered the biological mechanism involved in this process, which could point the way to potential therapies. The findings are published in the April 27 online edition of Stem Cells and Development.

Agencies should use common approach to evaluate risks pesticides pose to endangered species

WASHINGTON -- When determining the potential effects pesticides could pose to endangered or threatened species, the U.S. Environmental Protection Agency, National Marine Fisheries Service (NMFS), and Fish and Wildlife Service (FWS) should use a common scientific approach, says a new report from the National Research Council. Specifically, the agencies should use a risk assessment approach that addresses problem formulation, exposure analysis, effects analysis, and risk characterization.

Less is more when it comes to investment choices, says new study

Toronto – The best investment portfolios are selected from the widest array of choices, right?

Not so, says a new study authored by researchers at the University of Toronto's Rotman School of Management and the Bank of Canada. It says that a shorter "menu" of options is often better than a longer one. That's because "menu-setters" who develop shorter lists have superior selection skills, on average. The conclusion goes against findings in other research suggesting that more choices lead to better outcomes.

Zebrafish study suggests that vitamin B2 (riboflavin) is an antidote to cyanide poisoning

With the remains of a recent lottery winner having been exhumed for foul play related to cyanide poisoning, future winners might wonder what they can do to avoid the same fate. A new report in The FASEB Journal involving zebrafish suggests that riboflavin, also known as vitamin B2, may mitigate the toxic effects of this infamous poison. In addition, the report shows that zebrafish are a viable model for investigating the effects of cyanide on humans.

Synthetic derivatives of THC may weaken HIV-1 infection to enhance antiviral therapies

A new use for compounds related in composition to the active ingredient in marijuana may be on the horizon: a new research report published in the Journal of Leukocyte Biology shows that compounds that stimulate the cannabinoid type 2 (CB2) receptor in white blood cells, specifically macrophages, appear to weaken HIV-1 infection. The CB2 receptor is the molecular link through which the pharmaceutical properties of cannabis are manifested.

Intervention can prevent PPD in adolescents

By targeting the factors that may play a significant role in the development of postpartum depression (PPD) in adolescent mothers, researchers at Women & Infants Hospital of Rhode Island believe they have found a way to prevent it.

Shifting the burden of recycling

Over the past two decades governments around the world have been experimenting with a new strategy for managing waste. By making producers responsible for their products when they become wastes, policy makers seek to significantly increase the recycling—and recyclability—of computers, packaging, automobiles, and household hazardous wastes such as batteries, used oil motor, and leftover paint—and save money in the process.