Body

DALLAS – July 10, 2013 – Researchers at UT Southwestern Medical Center report the identification of a new cellular source for an important disease-fighting protein used in the body's earliest response to infection.

The protein interferon-gamma (IFN-γ) keeps viruses from replicating and stimulates the immune system to produce other disease-fighting agents. Neutrophils, the newly identified cellular source of the protein, are the major component of the pus that forms around injured tissue.

Boston – July 10, 2013 – Researchers at Joslin Diabetes Center have discovered that when excessive PKC beta is found in the endothelium, the thin layer of cells that line blood vessels, atherosclerosis is exacerbated. Their findings were published on-line on June 11 by Circulation Research.

For people with diabetes, the increased risk of cardiovascular disease is an unfortunate reality. This includes atherosclerosis, a condition where the walls of the artery thicken due to accumulating fatty deposits, which can lead to heart attack and stroke.

CHAPEL HILL, N.C. — Different factors influence delay between diagnosis and first course of treatment for breast cancer for African-American and White women.

WEST LAFAYETTE, Ind. -- Researchers have developed a concept to potentially improve delivery of drugs for cancer treatment using nanoparticles that concentrate and expand in the presence of higher acidity found in tumor cells.

New insights into why obese cigarette smokers experience a high risk of heart disease suggest that cigarette smoke affects the activity of hundreds of key genes that both protect the heart and lungs and expose them to damage. The study, published in ACS' Chemical Research in Toxicology, suggests that the effects may be especially profound in obese nonsmokers who inhale "sidesteam smoke" from cigarettes smoldering nearby.

EAST LANSING, Mich. — Major depression is a serious public health problem among older adults in the United States, but tends to affect ethnic groups differently, finds new research led by a Michigan State University scholar.

According to a survey of nearly 2,000 people aged 50 and older, whites and blacks of Caribbean descent experience much higher rates of major depression than African-Americans.

The masses of plastic debris that float over large areas of the world's oceans have become new ecological communities that scientists have named the "Plastisphere." Their report in the ACS journal Environmental Science & Technology suggests that these novel habitats in the North Atlantic Ocean may harbor potential disease-causing microbes.

Scientists are making strides toward unraveling the surprisingly complex chemistry underpinning that axiom of infant feeding "breast is best," according to an article in the current edition of Chemical & Engineering News. C&EN is the weekly newsmagazine of the American Chemical Society, the world's largest scientific society.

SEATTLE — More people are running, biking, and exercising in other ways in hundreds of US counties, according to new research from the Institute for Health Metrics and Evaluation (IHME) at the University of Washington.

WASHINGTON, DC — In nearly every major cause of premature death – from ischemic heart disease to diabetes to interpersonal violence – the United States trails its economic peers, according to new research from a global collaborative of scientists led by the Institute for Health Metrics and Evaluation (IHME) at the University of Washington.

Working near the Temple Mount in Jerusalem, Hebrew University of Jerusalem archaeologist Dr. Eilat Mazar has unearthed the earliest alphabetical written text ever uncovered in the city.

The inscription is engraved on a large pithos, a neckless ceramic jar found with six others at the Ophel excavation site. According to Dr. Mazar, the inscription, in the Canaanite language, is the only one of its kind discovered in Jerusalem and an important addition to the city's history.

A new species of rare and beautiful plant has been described from the biodiversity rich Peninsular Malaysia. Ridleyandra chuana is endemic to the region and only known from two small montane forest populations. The conservation status of this recently described delicate flower is assessed as Endangered due to its restricted distribution. The new species was described and illustrated in the open access journal PhytoKeys.

When did people first begin to express their feelings with flowers? It turns out that in prehistoric times, Mount Carmel residents in what today is northern Israel buried their dead on a literal bed of fragrant wild flowers, such as Judean sage, as well as blooming plants of the mint and figwort families. Assuming they had the same positive associations with flowers that we do today, these ancient humans must have sought to ensure for the deceased a pleasant passage from the world of the living.

In Bolivia, in the largest continuous salt desert in the world, researchers from the Polytechnic University of Catalonia have found a bacterium that stores large amounts of PHB, a prized polymer. This biodegradable plastic is used by the food and pharmaceutical industries, for example to produce nanospheres to transport antibiotics.

Photosynthesis takes place in specialized membrane systems, made up of stacked disks linked together by unstacked planar leaflets. A team of Ludwig-Maximilians-Universitaet (LMU) in Munich has now identified a protein that tucks the membrane in at the edge of each stack.

Scanning electron microscopy (SEM) micrograph of a chloroplast in maize (Zea mays) showing thylakoids (green) and assimilation starch granules (grey). (Prepared by freeze fracturing; micrograph is pseudo-colored.) (Source: G. Wanner LMU)