Body

Scientists discover kill-switch controls immune-suppressing cells

Scientists have uncovered the mechanism that controls whether cells that are able to suppress immune responses live or die.

The discovery of the cell death processes that determine the number of 'regulatory T cells' an individual has could one day lead to better treatments for immune disorders.

Sexual reproduction only second choice for powdery mildew

Powdery mildew is one of the most dreaded plant diseases: The parasitic fungus afflicts crops such as wheat and barley and is responsible for large harvest shortfalls every year. Beat Keller and Thomas Wicker, both plant biologists from the University of Zurich, and their team have been analyzing the genetic material of wheat mildew varieties from Switzerland, England and Israel while the team headed by Paul Schulze-Lefert at the Max Planck Institute for Plant Breeding Research in Cologne studies the genetic material of barley mildew.

Baseball players enjoy successful long-term results after elbow surgery

CHICAGO, IL – Baseball players undergoing ulnar collateral ligament (UCL) surgery are able to return to the same or higher level of competition for an extended period of time, according to research presented today at the American Orthopaedic Society for Sports Medicine's (AOSSM) Annual Meeting in Chicago, IL.

Knee cartilage repair technique shows improvement in patient outcomes and regeneration

A natural tissue graft can spur regeneration of cartilage and improve symptoms in patients who have cartilage damage in their knee, according to a study by researchers from Hospital for Special Surgery. The new research, the first case-series evaluation of De Novo NT Natural Tissue Graft, will be presented at the annual meeting of the American Orthopaedic Society for Sports Medicine (AOSSM), to be held July 11-14, in Chicago.

Study finds strong pregnancy outcomes for survivors of childhood cancer

BOSTON -- Although women who survived childhood cancer face an increased risk of infertility, nearly two-thirds of those who tried unsuccessfully to become pregnant for at least a year eventually conceived, according to clinical researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Brigham and Women's Hospital. This is comparable to the rate of eventual pregnancy among all clinically infertile women.

Stem cell clues uncovered

Baltimore, MD—Proper tissue function and regeneration is supported by stem cells, which reside in so-called niches. New work from Carnegie's Yixian Zheng and Haiyang Chen identifies an important component for regulating stem cell niches, with impacts on tissue building and function. The results could have implications for disease research. It is published by Cell Stem Cell.

Research finds racial/ethnic disparities in health care among older male cancer survivors

WINSTON-SALEM, N.C. – July 12, 2013 – Older African-American and Hispanic men who have survived cancer are less likely than their white counterparts to see a specialist or receive basic preventive care, such as vaccinations, according to new research from Wake Forest Baptist Medical Center.

Researchers examined racial/ethnic disparities in health care receipt among a nationally representative sample of male cancer survivors. They found that disparities are evident among older, but not younger, cancer survivors, despite their access to Medicare.

Young job seekers, check your privacy settings!

EVANSTON, Ill. --- Social media websites can be a boon for employers scoping out job applicants, and that's bad news for certain groups of young people, according to a new Northwestern University study.

Researchers found that -- among young adults -- men, Hispanics and those with lower Internet skills are the least likely to keep employment-related audiences in mind when it comes to their online profiles. Women, whites and those with higher Internet skills are more likely to actively manage their social media privacy settings as they seek a job or maintain employment.

Exploring gender dimensions of treatment programs for neglected tropical diseases in Uganda

TORONTO, ON – Males and females face different challenges in accessing treatment for neglected tropical diseases (NTDs), according to a new study from researchers at the University of Toronto Dalla Lana School of Public Health, Uganda Ministry of Health and Imperial College London. The study, published by PLOS Neglected Tropical Diseases on July 11, explores the role of gender in access to treatment in the Uganda National Neglected Tropical Disease Control Program.

Alarmingly high substance abuse rates found among street children in low-income countries

INDIANAPOLIS -- Millions of children worldwide live on the streets. A review and analysis of 50 studies on substance abuse by street children in 22 resource-constrained countries has found lifetime substance use to be both common and high, posing serious threats to their health as well as for their chances for reintegration into society.

Interspecies transplant works in first step for new diabetes therapy

CHICAGO --- In the first step toward animal-to-human transplants of insulin-producing cells for people with type 1 diabetes, Northwestern Medicine® scientists have successfully transplanted islets, the cells that produce insulin, from one species to another. And the islets survived without immunosuppressive drugs.

Northwestern scientists developed a new method that prevented rejection of the islets, a huge problem in transplants between species, called xenotransplantation.

Study finds surprising benefits about dairy cow inflammation

MANHATTAN, Kan. -- Inflammation. The word typically has a negative connotation. Arthritis … infection … numerous maladies come to mind.

But a Kansas State University researcher found that inflammation that occurs naturally in dairy cows the first few days after giving birth may play a surprisingly beneficial role in the complex process of going from late pregnancy to lactation.

On the trail of bacteria

The bacterium Staphylococcus aureus (S. aureus) is commonly found in nature and frequently colonizes the skin and the upper respiratory tract of humans. A healthy immune system can fight the microorganism but once the immune system is weakened the pathogen can spread and lead to life-threatening diseases of the lungs, the heart and other organs. Moreover, S. aureus produces toxins in foods and can cause serious food poisoning. Its effects are not confined to humans: in cattle, S.

High folate gestational and post-weaning diets in Wistar rat offspring

During pregnancy, women are normally advised to take high amounts of multivitamin supplements. In particular, folate is recommended to reduce the risk of neural tube defects in newborns. The problem is that, although vitamins are critical in fetal development, high vitamin doses during pregnancy may cause undesired effects on the offspring later in life (in rats, an obesogenic phenotype is typically observed).

Exploring gender dimensions of treatment programmes for neglected tropical diseases in Uganda

TORONTO, ON – Males and females face different challenges in accessing treatment for neglected tropical diseases (NTDs), according to a new study from researchers at the University of Toronto Dalla Lana School of Public Health, Uganda Ministry of Health and Imperial College London. The study, published by PLOS Neglected Tropical Diseases on July 11, explores the role of gender in access to treatment in the Uganda National Neglected Tropical Disease Control Program.