Body

Philadelphia, PA, August 15, 2013 – German researchers have identified four biomarkers that correctly determine malignancy of urinary bladder cancers and contribute to the accurate prediction of patient outcomes. Their results are published in the September issue of The Journal of Molecular Diagnostics.

HOUSTON – (Aug. 15, 2013) – A multi-institutional team led by Dianna Milewicz, M.D., Ph.D., of The University of Texas Health Science Center at Houston (UTHealth) has found a recurrent genetic mutation that has been linked to deadly thoracic aortic dissections in family members as young as 17 years of age.

RIVERSIDE, Calif. — Transposons are DNA elements that can multiply and change their location within an organism's genome. Discovered in the 1940s, for years they were thought to be unimportant and were called "junk DNA." Also referred to as transposable elements and jumping genes, they are snippets of "selfish DNA" that spread in their host genomes serving no other biological purpose but their own existence.

BOSTON (August 15, 2013) -- In a study published on line this week in the journal Human Molecular Genetics, Drs. Donita Garland, Rosario Fernandez-Godino, and Eric Pierce of the Ocular Genomics Institute at the Massachusetts Eye and Ear, Harvard Medical School, along with their colleagues, reported the unexpected finding that in mice genetically engineered to have an inherited form of macular degeneration, turning off the animals' complement system, a part of the immune system, prevented the disease.

Scientists working at the Research Center on Aging at the Health and Social Services Centre — University Institute of Geriatrics of Sherbrooke (CSSS-IUGS) have been studying strategies for protecting retinal pigment epithelium (RPE) cells. Dysfunction of the RPE is found in retinopathy and age-related macular degeneration, which is the leading cause of blindness of elderly people in developed countries.

New Rochelle, NY, August 15, 2013—The first institution-level model to estimate the amount of reactive nitrogen released into the environment—a contributor to smog, acid rain, and climate change—is enabling the University of Virginia to quantify its nitrogen footprint and take steps to reduce it.

CAMBRIDGE, Mass., August 15, 2013 – Aileron Therapeutics, Inc., a clinical stage biopharmaceutical company that is developing first-in-class therapeutics based on its proprietary Stapled Peptide drug platform, announced today the publication of preclinical data on ATSP-7041, a potent and selective stapled peptide re-activator of the wild type p53 tumor suppressor protein.

Children with a particularly lethal cancer could benefit from potentially life-saving treatment, following breakthrough work led by researchers at the University of New South Wales (UNSW).

A whole new class of drugs has been developed that, for the first time, targets the structure of the cancer cell.

UNSW researchers have provided proof that the therapy is effective in two types of cancers in the animal model. They are neuroblastoma, a cancer that affects children, and melanoma. The resulting paper has been published in Cancer Research.

While we're not necessarily aware of our heartbeat, this inner rhythm actually contributes to how we experience the body, and what belongs to it, according to research recently conducted at EPFL. A study to be published in the journal Psychological Science later this year supports the idea that signals from our internal organs combine with visual information to contribute to self-consciousness.

MEDFORD/SOMERVILLE, Mass. – In two recently published papers, Tufts University School of Engineering researchers have established new techniques for predicting the severity of seasonal cholera epidemics months before they occur and with a greater degree of accuracy than other methods based on remote satellite imaging. Taken together, findings from these two papers may provide the essential lead time to strengthen intervention efforts before the outbreak of cholera in endemic regions.

Canadian high schools with anti-homophobia policies or gay-straight alliances (GSAs) that have been in place for three years or more have a positive effect on both gay and straight students' problem alcohol use, according to a new study by University of British Columbia researchers.

GSAs are student-led clubs of lesbian, gay, bisexual, transgender, queer or questioning (LGBTQ) youth and their straight allies. Their purpose is to provide support and advocacy and help make schools more inclusive.

A new analysis has found that breastfeeding for more than six months may safeguard nonsmoking mothers against breast cancer. The same does not seem to hold true for smoking mothers, though. Published early online in the Journal of Clinical Nursing, the findings add to the list of benefits of breastfeeding for women and their babies.

Infection by human immunodeficiency virus (HIV) causes acquired immunodeficiency syndrome (AIDS), a debilitating disorder in which progressive weakening of the immune system makes affected individuals more susceptible to potentially life-threatening infections and chronic diseases. Despite advances in the treatment and management of AIDS, there is no cure, and HIV infection remains a major global health problem. According to the WHO, there were an estimated 34 million infected individuals in 2011.

ANN ARBOR --- Facebook helps people feel connected, but it doesn't necessarily make them happier, a new study shows.

Facebook use actually predicts declines in a user's well-being, according to a University of Michigan study that is the first known published research examining Facebook influence on happiness and satisfaction.

The study about the use of Facebook, a free networking website, appears online in PLOS ONE.

A new analysis of ostriches reveals that a computer model of long-necked sauropods used to simulate the dinosaurs' movements, featured in BBC's Walking with Dinosaurs and the focus of an installation at the American Museum of Natural History, New York, does not correctly reconstruct how flexible their necks were. The results are published August 14 in the open access journal PLOS ONE by Matthew Cobley from the University of Utah, with colleagues from the University of Bristol and Natural History Museum, London.