Body

A new light on the mechanisms of early stage liver reperfusion injury

Reperfusion of a previously ischemic tissue is associated with additional injury leading to structural and functional alterations in many organs including the liver. The injury induced during reperfusion is evolved a biphasic pattern consisting of an early stage started upon reoxygenation and a delayed phase. It is thought that reactive oxygen species formation during reperfusion induces a cascade of series of cellular events that eventually leads to hepatocellur injury.

A potential anti-ulcer herb medicine: Rocket 'Eruca sativa'

Gastric ulcer is an illness that affects a considerable number of people worldwide. Although the introduction of proton-pump inhibitors to the classic anti-ulcer therapy has revolutionized treatment of peptic ulcers and other gastrointestinal disorders, there is still no complete cure for this disease. It has been shown that long term use of these drugs leads to various adverse and side effects. Relapses of the malady, ineffectiveness of different drug regimens and even resistance to drugs are emerging.

Is it reasonable to perform polypectomy without interruption of anticoagulation?

Currently, patients taking anticoagulants to prevent stroke and blood clots are often recommended to stop these medications in order to perform colonoscopy with removal of polyps.

However, interruption of these medications can place patients at risk of stroke and blood clots. A group led by Shai Friedland at the VA Palo Alto hospital in California reported their experience removing small colon polyps without interrupting anticoagulation. Their study will be published on April 28, 2009 in the World Journal of Gastroenterology

4-in-1

Patients with mild to moderate OSA may benefit from exercise

Practicing certain tongue and pharyngeal exercises may reduce symptoms of mild to moderate obstructive sleep apnea (OSA), according to new research being published in the second issue for May of the American Journal of Respiratory and Critical Care Medicine.

Although CPAP is the gold standard treatment for severe OSA, the vast majority of subjects from epidemiological studies have mild or moderate OSA. The compliance to CPAP among mild to moderate OSA is variable, and there are only a few forms of alternative treatments for this large number of subjects and patients.

Insect gene expression responds to diet

Cabbage looper caterpillars (Trichoplusia ni) are able to alter the expression of genes associated with metabolism, homeostasis and immunity in response to feeding on plants carrying bacteria. Research published in BioMed Central's open access journal Frontiers in Zoology has shown that, as well as tailoring gene expression within their own digestive systems, the insects are able to pass this information along to their offspring.

Minority groups pick up worst European eating habits

Immigrant populations in Europe face an increased risk of diet-related diseases as they adjust to a 'Western' lifestyle, according to scientists at the University of Leeds.

A recent study shows that the dietary habits of immigrants change when they move to European countries. According to the research, immigrant populations replace the healthy components of their native diet with the worst aspects of western diets, such as processed and fast foods.

Putting 'effect' into comparative-effectiveness research

HOUSTON – (May 6, 2009) - With the federal government putting $1.1 billion into comparative-effectiveness research, two Baylor College of Medicine researchers advocate investing in finding ways to put that science into practice in doctors' offices and clinics across the nation.

Superior entrepreneurial performance is not driven by technical knowledge

Durham, N.C.—May 6, 2009—Entrepreneurs in high-technology industries often have significant prior industry experience. A new study in Strategic Management Journal reveals that this experience is critical to their success. Surprisingly, however, it is mainly the non-technical knowledge that founders gain from their experience with prior firms that affects increased achievement at their new firms, rather than direct technical spillovers from the former parent to a new venture.

Swine flu genes dissimilar to past pandemics

Some genetic markers of influenza infection severity have been identified from past outbreaks. Researchers have failed to find most of these markers, described in the open access journal BMC Microbiology, in samples of the current swine-flu strain.

Novel gene predicts local recurrence in early onset breast cancer

HOUSTON - A newly discovered gene known as DEAR1 is mutated in breast cancer and is an independent predictor of local recurrence-free survival in early-onset breast cancer, a research team headed by scientists at The University of Texas M. D. Anderson Cancer Center reports in the journal PLoS Medicine.

Treatment for extreme nausea, vomiting during pregnancy

Montreal, May 6, 2009 – Nausea and vomiting are telltale indicators of pregnancy, affecting more than 80 percent of future mothers. For a few moms-to-be, symptoms can become so severe that hospitalization is required.

IPM reduces cockroaches and allergens in schools

For years, scientists have associated growing asthma rates among children with exposure to cockroach allergens, especially among inner-city children. A new study in the May issue of Journal of Medical Entomology entitled "German Cockroach Allergen Levels in North Carolina Schools: Comparison of Integrated Pest Management and Conventional Cockroach Control" shows that using integrated pest management (IPM) to control cockroaches is more effective at reducing cockroaches and their allergens than conventional methods which do not use IPM.

Random picks better than complicated process in gene identification

WEST LAFAYETTE, Ind. - Researchers at Purdue University have found a way to save time, money and a little frustration in searches for specific genes that shed light on the biological processes associated with all forms of life.

Hebrew University researchers neutralize tumor growth in embryonic stem cell therapy

Jerusalem, May 5, 2009 – Researchers at the Hebrew University of Jerusalem have discovered a method to potentially eliminate the tumor-risk factor in utilizing human embryonic stem cells. Their work paves the way for further progress in the promising field of stem cell therapy.