Body

Will my breast cancer spread? Discovery may predict probability of metastasis

SALT LAKE CITY—Researchers from Huntsman Cancer Institute (HCI) at the University of Utah have discovered a new way to model human breast cancer that could lead to new tools for predicting which breast cancers will spread and new ways to test drugs that may stop its spread. Their results are published online today in the journal Nature Medicine.

How plants sense low oxygen levels to survive flooding

RIVERSIDE, Calif. – As countries such as Pakistan, Bangladesh, Vietnam and parts of the United States and United Kingdom have fallen victim to catastrophic flooding in recent years, tolerance of crops to partial or complete submergence is a key target for global food security. Starved of oxygen, crops cannot survive a flood for long periods of time, leading to drastic reductions in yields for farmers.

UC Davis researchers discover complexities of DNA repair

(SACRAMENTO, Calif.) —An international team of scientists led by UC Davis researchers has discovered that DNA repair in cancer cells is not a one-way street as previously believed. Their findings show instead that recombination, an important DNA repair process, has a self-correcting mechanism that allows DNA to make a virtual u-turn and start over.

B-lymphocyte depletion using the anti-CD20 antibody rituximab in chronic fatigue syndrome

Chronic fatigue syndrome (CFS) may be alleviated by the anti-cancer drug Rituximab, suggesting that the source of the disease could lie in the immune system, according to a new study published Oct. 19 in the online journal PLoS ONE. Uncertainty about the cause of CFS, which is characterized by extreme, unexplained exhaustion, among other symptoms, has led to much debate, but the authors of this recent study believe they may have found the answer.

Laser's precision and simplicity could revolutionize cataract surgery

ORLANDO, Fla. –- October 23, 2011 — Two new studies add to the growing body of evidence that a new approach to cataract surgery may be safer and more efficient than today's standard procedure. The new approach, using a special femtosecond laser, is FDA-approved, but not yet widely available in the United States. It's one of the hottest topics this week at the 115th Annual Meeting of the American Academy of Ophthalmology. Research reported today by William W.

E-counselling shows dramatic results in lowering blood pressure

Vancouver – E-counselling can significantly lower blood pressure, improve lifestyle and enhance quality of life, says Heart and Stroke Foundation researcher Dr. Robert Nolan.

"E-counselling has the potential to strengthen the effects of medical treatment for high blood pressure," Dr. Nolan told the Canadian Cardiovascular Congress, which is co-hosted by the Heart and Stroke Foundation and the Canadian Cardiovascular Society. "We found that it led to an almost double decrease in the blood pressure levels of participants compared to those who did not receive the e-counselling."

Burden of osteoporotic fractures increases dramatically in the Middle East and Africa

A new audit report issued today by the International Osteoporosis Foundation (IOF) shows that osteoporosis is a serious and growing problem throughout the Middle East and parts of Africa.

Preventing cancer development inside the cell cycle

Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells. The study shows the significant role that protein networks can play in a cell leading to the development of cancer.

Why do some athletes choke under pressure?

Athletes know they should just do their thing on the 18th hole, or during the penalty shootout, or when they're taking a 3-point shot in the last moments of the game. But when that shot could mean winning or losing, it's easy to choke. A new article published in Current Directions in Psychological Science, a journal of the Association for Psychological Science, looks at why paying too much attention to what you're doing can ruin performance.

Physical stimuli: Plants 'feel' the force

"Picture yourself hiking through the woods or walking across a lawn," says Elizabeth Haswell, PhD, assistant professor of biology in Arts & Sciences at Washington University in St. Louis. "Now ask yourself: Do the bushes know that someone is brushing past them? Does the grass know that it is being crushed underfoot? Of course, plants don't think thoughts, but they do respond to being touched in a number of ways."

European studies on risks of hepatocellular carcinoma

Among known risk factors for hepatocellular cancer, smoking, obesity, and heavy alcohol consumption, along with chronic hepatitis B and C infection, contribute to a large share of the disease burden in Europe, according to a cohort study published online October 21 in the Journal of the National Cancer Institute.

Trio of studies support use of PET/CT scans as prostate cancer staging tool

ROCHESTER, Minn. -- Recent studies have suggested that C-11 choline positron emission tomography/computerized tomography (PET/CT) scans can be utilized as a staging and potentially therapeutic tool in prostate cancer. The results of three studies, released today during a meeting of the North Central Section of the American Urological Association (http://www.ncsaua.org/default.aspx), validate findings in Europe and expand the potential use of C-11 choline PET scans.

Commonly used 3-drug regimen for idiopathic pulmonary fibrosis found harmful

The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, has stopped one arm of a three arm multi-center, clinical trial studying treatments for the lung-scarring disease idiopathic pulmonary fibrosis (IPF) for safety concerns. The trial found that people with IPF receiving a currently used triple-drug therapy consisting of prednisone, azathioprine, and N-acetylcysteine (NAC) had worse outcomes than those who received placebos, or inactive substances.

Researchers generate first complete 3-D structures of bacterial chromosome

WORCESTER, Mass. — A team of researchers at the University of Massachusetts Medical School, Harvard Medical School, Stanford University and the Prince Felipe Research Centre in Spain have deciphered the complete three-dimensional structure of the bacterium Caulobacter crescentus's chromosome. Analysis of the resulting structure —published this week in Molecular Cell — has revealed new insights into the function of genetic sequences responsible for the shape and structure of this genome.

Social isolation: Are lonely consumers actually loners or conformers?

Despite the proliferation of social networks, many Americans feel alone and isolated. According to a new study in the Journal of Consumer Research, lonely individuals behave differently in the marketplace than people with strong social networks.