Body

Unique bipolar compounds enhance functionality of organic electronics

Researchers often work with a narrow range of compounds when making organic electronics, such as solar panels, light emitting diodes and transistors. Professor Tim Bender and Ph.D. Candidate Graham Morse of University of Toronto's Department of Chemical Engineering and Applied Chemistry have uncovered compounds that exhibit unique and novel electro-chemical properties.

Common bacteria cause some colon tumors by altering peroxide-producing gene

Working with lab cultures and mice, Johns Hopkins scientists have found that a strain of the common gut pathogen Bacteroides fragilis causes colon inflammation and increases activity of a gene called spermine oxidase (SMO) in the intestine. The effect is to expose the gut to hydrogen peroxide – the caustic, germ-fighting substance found in many medicine cabinets -- and cause DNA damage, contributing to the formation of colon tumors, say the scientists.

Researchers discover why measles spreads so quickly

Laval, Canada -- Measles virus is perhaps the most contagious virus in the world, affecting 10 million children worldwide each year and accounting for 120,000 deaths. An article published in the Nov. 2, 2011 issue of Nature explains why this virus spreads so rapidly. The discovery by Roberto Cattaneo, Ph.D., at Mayo Clinic in Rochester, MN, in collaboration with Veronika von Messling, DVM, at the Centre INRS–Institut Armand-Frappier and research teams at several other universities opens up promising new avenues in cancer treatment.

Research aims to prevent diabetic kidney failure

The enzyme arginase-2 plays a major role in kidney failure, and blocking the action of this enzyme might lead to protection against renal disease in diabetes, according to researchers.

"We believe these arginase inhibitors may be one of the new targets that can slow down the progression of, or even prevent the development of, end-stage renal disease," said Alaa S. Awad, assistant professor of nephrology, Penn State College of Medicine.

Coasts' best protection from bioinvaders falling short

Invasive species have hitchhiked to the U.S. on cargo ships for centuries, but the method U.S. regulators most rely on to keep them out is not equally effective across coasts. Ecologists from the Smithsonian Environmental Research Center have found that ports on the East Coast and the Gulf of Mexico are significantly less protected than ports on the West Coast.

Food for thought: Contravening lay beliefs of eating at heart of our dietary disasters

Waste not, want not. Breakfast is the most important meal of the day. Don't snack before supper; you'll ruin your appetite.

How do green algae react to carbon nanotubes?

and German.

Carbon nanotubes (CNTs) are up to 100,000 times thinner than a human hair and as light as plastic. Despite this they have a higher tensile strength than steel, are harder than diamond and conduct electricity better than copper. These properties make CNTs a raw material with a very promising future. All over the world possible applications are being investigated, including use in solar cells, plastics, batteries, medical technology and the purification of drinking water.

Molecule serves as a key in some protein interactions

Research led by St. Jude Children's Research Hospital scientists has identified an unexpected mechanism facilitating some protein interactions that are the workhorses of cells and, in the process, identified a potential new cancer drug development target.

Why is the measles virus so contagious?

An international collaboration involving Inserm has revealed how the measles virus leaves the body of an infected person to contaminate another individual. The researchers have identified a key receptor, located in the trachea, which allows the virus to spread through the air rapidly from one organism to another. The receptor, nectine-4, is also known to be a biomarker for some cancers.

This research appeared in a letter, dated 2 November 2011, published in Nature.

Protein causes varicose veins

Varicose veins, sometimes referred to as "varices" in medical jargon, are usually just a cosmetic problem if they occur as spider veins. In their advanced stage, however, they pose a real health threat. In people with this widespread disorder, the blood is no longer transported to the heart unhindered but instead pools in the veins of the leg. This is because the vessel walls or venous valves no longer function adequately. Dr. Thomas Korff and his group at the Division of Cardiovascular Physiology (Director: Prof.

Researchers identify structure of apolipoprotein

(Boston) - Using a sophisticated technique of x-ray crystallography, researchers Xiaohu Mei, PhD, and David Atkinson, PhD, from Boston University School of Medicine (BUSM) have for the first time obtained an "image" of the structure and the precise arrangement of the atoms in a truncated form of the apolipoprotein A-I (apoA-I) molecule. The findings, which appear in the November issue of the Journal of Biological Chemistry, may lead to the development of new drugs to treat obesity, stroke and diabetes.

Dead of winter is tough on arthritis sufferers

CHICAGO --- As cold winter weather sets in and daylight hours dwindle, many older Chicagoans with arthritis tend to sit idle, missing out on the daily dose of physical activity they need to improve their health, according to a Northwestern Medicine study.

"We found that there's a huge difference in trying to get these patients to be active in the winter and trying to get them to be active in the summer," said Joe Feinglass, a research professor of medicine at Northwestern University Feinberg School of Medicine.

Birth cohort screening for hepatitis C is cost effective, could save thousands of lives each year

PHILADELPHIA, November 4, 2011 – According to a new study being published early online in Annals of Internal Medicine, the flagship journal of the American College of Physicians, birth cohort screening for hepatitis C is cost effective in the primary care setting. A proactive screening strategy could identify over 800,000 currently unidentified cases, which could save many thousands of lives each year.

Biologists use flies and mice to get to the heart of Down syndrome

A novel study involving fruit flies and mice has allowed biologists to identify two critical genes responsible for congenital heart defects in individuals with Down syndrome, a major cause of infant mortality and death in people born with this genetic disorder.

A new definition for periprosthetic joint infection

(PHILADELPHIA) – A rise in periprosthetic joint infection (PJI) rates has the orthopedic community moving to develop it's first-ever agreed upon definition and diagnostic criteria to help better treat patients.