Body

Chemotherapy plus targeted therapies shows improved survival in advance-stage lung cancer patients

The combination of traditional chemotherapy agents with targeted therapies called monoclonal antibodies showed no safety concerns and improved survival in patients with advanced non-small cell lung cancer according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, sponsored by ASTRO, ASCO, IASLC and the University of Chicago.

Research demonstrates differing genetic makeup of lung cancer in African-American patients

The tumors of African-American non-small cell lung cancer patients are more likely to carry a higher number of copies of the epidermal growth factor receptor (EGFR) gene and fewer mutations of EGFR itself than Caucasians according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, cosponsored by ASTRO, ASCO, IASLC and the University of Chicago.

These genetic factors have been shown to predict long-term outcome and tumor responses when taking erlotinib and gefitinib – common EGFR inhibitor drugs.

Hope for treating relapse to methamphetamine abuse

UPTON, NY — A new study at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory suggests that vigabatrin (a.k.a. gamma vinyl-GABA, or GVG) blocks drug-seeking behavior in animals previously trained to associate methamphetamine with a particular environment. Specifically, animals pre-treated with vigabatrin lost interest in spending time in a location where they had previously been given methamphetamine. The results will appear in the February 2009 issue of Synapse, now available online.

Novel 4-drug combination proves safe for lung cancer treatment

CHICAGO - The four drug-combination of carboplatin and paclitaxel, with the targeted therapies bevacizumab (Avastin) and cetuximab (Erbitux), is safe and may improve survival for patients with advanced lung cancer, according to a cooperative group study led by The University of Texas M. D. Anderson Cancer Center.

Networks of small habitat patches can preserve urban biodiversity

Sets of small and seemingly insignificant habitat patches that are within reach for mobile species may under certain circumstances, as a group, provide an acceptable alternative to larger and contiguous habitats. This finding can make preservation of important ecological functions possible even in urban and other heavily exploited areas.

Nanoparticles trigger cell death?

Nanoparticles that are one milliard of a metre in size are widely used, for example, in cosmetics and food packaging materials. There are also significant amounts of nanoparticles in exhaust emissions. However, very little is yet known of their health effects, because only a very small portion of research into nanoparticles is focused on their health and safety risks. Nanoparticles have even been dubbed the asbestos of the 2000s bys some researchers, and therefore a considerable threat to people's health.

Vitamin C lowers levels of inflammation biomarker considered predictor of heart disease

Berkeley -- A new study led by researchers at the University of California, Berkeley, adds to the evidence that vitamin C supplements can lower concentrations of C-reactive protein (CRP), a central biomarker of inflammation that has been shown to be a powerful predictor of heart disease and diabetes. The same study found no benefit from daily doses of vitamin E, another antioxidant.

Traditional knowledge under threat: Faulty laws, lack of trust stymie promising advances

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Plastic surgeons warn of malnutrition in body contouring patients

ARLINGTON HEIGHTS, Ill. – Identifying malnutrition before surgery in massive weight loss patients seeking body contouring will significantly decrease surgical complications, accelerate wound healing, improve scar quality and boost patient energy levels, according to a study in the December issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

First live rhinoceros birth from frozen-thawed semen

Philadelphia, PA, November 13, 2008 – There may be less than 20,000 rhinoceros in the world, with one species perhaps already extinct and another with possibly only four animals remaining in the wild. As the populations of these animals age and become infirm, successful breeding becomes increasingly difficult.

Placebo acupuncture is associated with a higher pregnancy rate after IVF than real acupuncture

A study comparing the effects of real and placebo acupuncture on pregnancy rates during assisted reproduction has found that, surprisingly, placebo acupuncture was associated with a significantly higher overall pregnancy rate than real acupuncture.

Results of landmark study of HIV vaccine published in the Lancet

SEATTLE and WHITEHOUSE STATION, N.J., Nov. 12, 2008 -- Results from the Step study, a test-of-concept efficacy study of a Merck & Co., Inc. HIV vaccine candidate, were published online today in two papers in The Lancet. These analyses of the Step study are being conducted, presented and published to inform the continued search for an effective HIV vaccine.

Safety in numbers for community hospitals performing emergency angioplasty

Heart experts at Johns Hopkins have evidence that life-saving coronary angioplasty at community hospitals is safer when physicians and hospital staff have more experience with the procedure.

Cedars-Sinai Heart Institute researchers to present findings at annual Scientific Sessions

LOS ANGELES – Researchers from the Cedars-Sinai Heart Institute will participate in 42 presentations at the American Heart Association's annual Scientific Sessions being held in New Orleans, La., from Nov. 8 through 12. Among findings that will be shared by Cedars-Sinai cardiologists and their colleagues:

A large waist can almost double your risk of premature death, says huge Europe-wide study

Having a large waistline can almost double your risk of dying prematurely even if your body mass index is within the 'normal' range, according to a new study of over 350,000 people across Europe, published today in the New England Journal of Medicine.