Body

Burnt sugar derivative reduces muscle wasting in fly and mouse muscular dystrophy

A trace substance in caramelized sugar, when purified and given in appropriate doses, improves muscle regeneration in a mouse model of Duchenne muscular dystrophy. The findings are published today, Aug. 1, in the journal Skeletal Muscle.

Feeling left out can lead to risky financial decisions, research finds

HONOLULU – People who feel isolated are more inclined to make risker financial decisions for bigger payoffs, according to new research presented at the American Psychological Association's 121st Annual Convention.

Novel drug shuts down master protein key to lymphoma

NEW YORK (August 1, 2013) -- Researchers have discovered how an experimental drug is capable of completely eradicating human lymphoma in mice after just five doses. The study, led by researchers at Weill Cornell Medical College, sets the stage for testing the drug in clinical trials of diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin lymphoma, itself the seventh most frequently diagnosed cancer in the U.S.

Blocking key enzyme in cancer cells could lead to new therapy

Researchers from the University of Illinois at Chicago College of Medicine have identified a characteristic unique to cancer cells in an animal model of cancer -- and they believe it could be exploited as a target to develop new treatment strategies.

Arctic sea-ice loss has widespread effects on wildlife

With sea ice at its lowest point in 1,500 years, how might ecological communities in the Arctic be affected by its continued and even accelerated melting over the next decades?

Common genetic ancestors lived during roughly same time period, Stanford scientists find

STANFORD, Calif. — Mitochondrial Eve and Y-chromosomal Adam — two individuals who passed down a portion of their genomes to the vast expanse of humanity — are known as our most recent common ancestors, or MRCAs. But many aspects of their existence, including when they lived, are shrouded in mystery.

Now, a study led by the Stanford University School of Medicine indicates the two roughly overlapped during evolutionary time: from between 120,000 to 156,000 years ago for the man, and between 99,000 and 148,000 years ago for the woman.

Scientists find long-sought method to efficiently make complex anticancer compound

LA JOLLA, CA – August 1, 2013 – Scientists at The Scripps Research Institute (TSRI) have achieved the first efficient chemical synthesis of ingenol, a highly complex, plant-derived compound that has long been of interest to drug developers for its anticancer potential. The achievement will enable scientists to synthesize a wide variety of ingenol derivatives and investigate their therapeutic properties.

Temperature alters population dynamics of common plant pests

Temperature-driven changes alter outbreak patterns of tea tortrix -- an insect pest -- and may shed light on how temperature influences whether insects emerge as cohesive cohorts or continuously, according to an international team of researchers. These findings have implications for both pest control and how climate change may alter infestations.

As climate, disease links become clearer, study highlights need to forecast future shifts

Athens, Ga. – Climate change is affecting the spread of infectious diseases worldwide, according to an international team of leading disease ecologists, with serious impacts to human health and biodiversity conservation. Writing in the journal Science, they propose that modeling the way disease systems respond to climate variables could help public health officials and environmental managers predict and mitigate the spread of lethal diseases.

The when and where of the Y: Research on Y chromosomes finds new clues about human ancestry

ANN ARBOR, Mich. — More than 7 billion people live on this planet – members of a single species that originated in one place and migrated all over the Earth over tens of thousands of years.

But even though we all trace our family lineage to a few common ancestors, scientists still don't know exactly when and how those few ancestors started to give rise to the incredible diversity of today's population.

Scientists discover new type of protein modification, may play role in cancer and diabetes

LA JOLLA, CA – August 1, 2013 – Scientists at The Scripps Research Institute (TSRI) have discovered a new type of chemical modification that affects numerous proteins within mammalian cells. The modification appears to work as a regulator of important cellular processes including the metabolism of glucose. Further study of this modification could provide insights into the causes of diabetes, cancer and other disorders.

Study finds physicians need to better recognize use of herbal supplements while breastfeeding

(Boston) – In an article published in this month's issue of Pediatrics In Review, researchers from Boston University School of Medicine (BUSM) stress the importance of physicians recognizing that many mothers use herbal supplements while breastfeeding in order to make accurate health assessments for both mother and child.

Advance in regenerative medicine could make reprogrammed cells safer while improving their function

NEW YORK (Aug. 1, 2013) -- The enormous promise of regenerative medicine is matched by equally enormous challenges. But a new finding by a team of researchers led by Weill Cornell Medical College has the potential to improve both the safety and performance of reprogrammed cells.

When it comes to skin cancer, pictures are worth 1,000 words

WATERLOO, Ont. (Thursday, August 1, 2013) – Seeing pictures of skin cancer motivates people to regularly check their own moles, according to a new research paper from the School of Public Health and Health Systems at the University of Waterloo.

The paper, published in the Journal of the American Academy of Dermatology, found that visual images of skin cancer are most effective in prompting skin self-examinations.

Removing a protein enhances defense against bacteria in CGD mice

Deletion of a protein in white blood cells improves their ability to fight the bacteria staphylococcus aureus and possibly other infections in mice with chronic granulomatous disease (CGD), according to a National Institutes of Health study. CGD, a genetic disorder also found in people, is marked by recurrent, life-threatening infections. The study's findings appear online in The Journal of Clinical Investigation.