Body

New process could advance use of healthy cells or stem cells to treat disease

In a discovery that may help speed use of "cell therapy" — with normal cells or stem cells infused into the body to treat disease — scientists are reporting development of a way to deliver therapeutic human cells to diseased areas within the body using a simple magnetic effect. Their report appears in ACS' journal Langmuir.

Self-regulation of the immune system suppresses defense against cancer

It is vital that the body's own immune system does not overreact. If its key players, the helper T cells, get out of control, this can lead to autoimmune diseases or allergies. An immune system overreaction against infectious agents may even directly damage organs and tissues.

Balancing the womb

New research hopes to explain premature births and failed inductions of labour. The study by academics at the University of Bristol suggests a new mechanism by which the level of myosin phosphorylation is regulated in the pregnant uterus.

The researchers, Dr Claire Hudson and Professor Andrés López Bernal in the School of Clinical Sciences and Dr Kate Heesom in the University Proteomics Facility and the School of Biochemistry, have discovered that phosphorylation of uterus proteins at specific amino acids have a key role in the regulation of uterine activity in labour.

How to break Murphy's Law

Murphy's Law is a useful scapegoat for human error: "If something can go wrong, it will." But, a new study by researchers in Canada hopes to put paid to this unscientific excuse for errors by showing that the introduction of verification and checking procedures can improve structural safety and performance and so prevent the application of the "law".

Exploiting Trichoderma: From food security to biotechnology

From improving food security to their use as biotechnology power horses, Trichoderma fungi are increasingly being exploited by industry. Current advances in the field are brought together and highlighted in a special issue of Microbiology published online on 27 December.

'Head-first' diversity shown to drive vertebrate evolution

The history of evolution is periodically marked by explosions in biodiversity, as groups of species try out a wide range of shapes and sizes. With a new analysis of two such adaptive radiations in the fossil record, researchers have discovered that these diversifications proceeded head-first.

To turn up the heat in chilies, just add water

Biologists have learned in recent years that wild chilies develop their trademark pungency, or heat, as a defense against a fungus that could destroy their seeds. But that doesn't explain why some chilies are hot and others are not.

Frankincense production 'doomed' warn ecologists

Trees that produce frankincense – used in incense and perfumes across the world and a key part of the Christmas story – are declining so dramatically that production of the fragrant resin could be halved over the next 15 years, according to a new study published in the British Ecological Society's Journal of Applied Ecology.

Get ready for spring - hay fever worse in spring than summer

Hay fever (runny nose, sneezing, itchy eyes) is caused by an allergy to pollen, and most commonly to grass pollen. These tiny grains bring misery to sufferers through spring and summer and pollen levels are often included as part of weather reports to help sufferers prepare. However new research published in BioMed Central's open access journal Clinical and Translational Allergy shows that, regardless of medication and other allergies, for the same grass pollen levels, hay fever symptoms are worse in the first half of the season than later on.

Salt policy makers eat too much salt at work

Salt policy makers in the Netherlands are consuming more than the average daily recommended salt intake of 6 grams in one hot meal at their work canteens, finds a study in the Christmas issue published on bmj.com today.

The authors, led by Dr Lizzy Brewster at the University of Amsterdam, say the policy makers eating at their staff canteens were consuming around 15.4 grams of salt a day. They warn that this amount of salt, compared to the recommended intake, translates to up to a 36% increase in premature death.

Doctors should stop using the phrase 'obs stable' in hospital notes

The phrase "obs stable" in hospital notes is ambiguous and does not reliably indicate a patient's health status, concludes a study in the Christmas issue published on bmj.com today.

Dr Gregory Scott and colleagues argue that the phrase is potentially misleading and advise doctors to stop using it and write the observations in full.

New analysis casts doubt on results of tobacco industry studies into safety of cigarette additives

New analysis casts doubt on results of tobacco industry studies into safety of cigarette additives

Published tobacco industry scientific research on the safety of cigarette additives cannot be taken at face value, according to an analysis led by Stanton Glantz from the Center for Tobacco Control Research and Education at the University of California in San Francisco, and published in this week's PLoS Medicine.

Single-sex vaccination is most effective at reducing HPV infection

In this week's PLoS Medicine, Johannes Bogaards of VU University, the Netherlands and colleagues use mathematical models to investigate whether vaccinating females only, males only, or both sexes is the best way to achieve the most effective reduction in the population prevalence of sexually-transmitted infections.

Sleep disorders common among police officers

CHICAGO – A survey of police officers indicated that about 40 percent have a sleep disorder, which was associated with an increased risk of adverse health, safety and performance outcomes, according to a study in the December 21 issue of JAMA.

Increase in resting heart rate over 10-year period linked with increased risk of heart disease death

CHICAGO – In a study that enrolled nearly 30,000 apparently healthy men and women, those who had an increase in their resting heart rate over a 10-year period had an increased risk of death from all causes and from ischemic heart disease, according to a study in the December 21 issue of JAMA.