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Children failing asthma therapy may have severe asthma with fungal sensitization

ATS 2012, SAN FRANCISCO –New research presented at the ATS 2012 International Conference in San Francisco suggests that a significant proportion of children with asthma failing Step 4 or greater therapy may have severe asthma with fungal sensitization (SAFS).

Baseline characteristics of children with mild persistent asthma predict response to ICS

ATS 2012, SAN FRANCISCO – A further analysis of a previously published National Heart, Lung, and Blood Institute (NHLBI) funded study of children with mild persistent asthma reports the relative benefits of inhaled corticosteroid (ICS) treatment varies among children with differing demographic and clinical characteristics.

Vitamin C improves pulmonary function in newborns of pregnant smoking women

ATS 2012, SAN FRANCISCO –Vitamin C supplementation in pregnant women who are unable to quit smoking significantly improves pulmonary function in their newborns, according to a new study.

Flu shot during pregnancy shows unexpected benefits in large study

May 22, 2012 – Ottawa – Getting a flu shot during pregnancy provides unanticipated benefits to the baby, according to the authors of a large population-based study examining the issue. Specifically, the study showed that H1N1 vaccination during the pandemic was associated with a significantly reduced risk of stillbirth, preterm birth and extremely small babies at birth.

How one strain of MRSA becomes resistant to last-line antibiotic

Researchers have uncovered what makes one particular strain of methicillin-resistant Staphylococcus aureus (MRSA) so proficient at picking up resistance genes, such as the one that makes it resistant to vancomycin, the last line of defense for hospital-acquired infections. They report their findings in mBio®, the online open-access journal of the American Society for Microbiology, on Tuesday May 22.

Correct treatment of common diabetic foot infections can reduce amputations

AT A GLANCE

NIH study shows poor quality malaria drugs pose threat

Poor quality antimalarial drugs lead to drug resistance and inadequate treatment that pose an urgent threat to vulnerable populations, according to a National Institutes of Health study published May 22 in The Lancet Infectious Diseases journal. Emergence of malaria strains that are resistant to artemisinin drugs on the Thailand-Cambodia border make it imperative to improve the drug supply, stressed the authors.

The Women's Health Initiative study and hormone therapy -- what have we learned 10 years on?

In July 2002 the publication of the first Women's Health Initiative (WHI) report caused a dramatic drop in Menopausal Hormone Therapy (HT ) use throughout the world. Now a major reappraisal by international experts, published as a series of articles in the peer-reviewed journal Climacteric (the official journal of the International Menopause Society), shows how the evidence has changed over the last 10 years, and supports a return to a "rational use of HT, initiated near the menopause".

Mayo Clinic: Pancreatic cancer may be detected with simple intestinal probe

JACKSONVILLE, Fla. — By simply shining a tiny light within the small intestine, close to that organ's junction with the pancreas, physicians at Mayo Clinic's campus in Florida have been able to detect pancreatic cancer 100 percent of the time in a small study. The light, attached to a probe, measures changes in cells and blood vessels in the small intestine produced by a growing cancer in the adjoining pancreas.

Final word: Task force recommends against PSA-based screening for prostate cancer

PHILADELPHIA, May 22, 2012 – Following a period for public comment, the United States Preventive Services Task Force (USPSTF) released its final recommendation for prostate cancer screening. The Task Force now recommends against PSA-based screening for all men, regardless of age. The final recommendations are being published early online in the May 22 issue of Annals of Internal Medicine, the flagship journal of the American College of Physicians (ACP).

Tufts Medical Center researchers finds marker in premies' saliva predicts readiness to feed by mouth

BOSTON (May 21) -- Tufts Medical Center researchers have shown that presence of a gene strongly linked to appetite regulation is highly predictive of a premature infant's readiness to feed orally. An analysis of just a drop of an infant's saliva could be the key to preventing many feeding problems and the expensive medical complications that can occur when infants are fed by mouth too early.

Taking cholesterol drugs in hospital may improve stroke outcomes

MINNEAPOLIS – A new study suggests that using cholesterol-lowering medications known as statins after having a stroke may increase the likelihood of returning home and lessen the chance of dying in the hospital. The research is published in the May 22, 2012, print issue of Neurology®, the medical journal of the American Academy of Neurology.

Hunter-gatherers and horticulturalist lifestyle linked to lower blood pressure increases

Hunter-gatherers and forager-horticulturalists who live off the land and grow what they need to survive have lower age-related increases in blood pressure and less risks of atherosclerosis, according to two new studies in the American Heart Association journal Hypertension.

Study finds moderate weight loss reduces levels of sex hormones linked to breast cancer risk

SEATTLE – Even a moderate amount of weight loss can significantly reduce levels of circulating estrogens that are associated with an increased risk of breast cancer, according to a study by researchers at Fred Hutchinson Cancer Research Center – the first randomized, controlled clinical trial to test the effects of weight loss on sex hormones in overweight and obese postmenopausal women, a group at elevated risk for breast cancer.

Study suggests obese patients have more advanced, aggressive papillary thyroid cancer

CHICAGO – A review of medical records of patients treated at an academic tertiary care center suggests that obese patients present to their physicians with more advanced stage and more aggressive forms of papillary thyroid cancer (PTC), according to a report published Online First by Archives of Surgery, a JAMA Network publication.