Body

CLEVELAND, Ohio (September 17, 2014)—The North American Menopause Society (NAMS) has published its key, evidence-based recommendations for the comprehensive care of midlife women—on everything from hot flashes to heart disease. The special feature, "The North American Menopause Society Recommendations for Clinical Care of Midlife Women," was published online today in the Society's journal Menopause. This is the first, comprehensive set of evidence-based recommendations for the care of midlife women freely available to all clinicians who care for women at this stage of life.

Transmission of bacterial infections, including MRSA and MSSA could be curbed by coating hospital surfaces with microscopic bumps that mimic the scaly surface of shark skin, according to research published in the open access journal Antimicrobial Resistance and Infection Control.

NEW YORK (17 September, 2014)—More than $100 trillion in cumulative public and private spending, and 1,700 megatons of annual carbon dioxide (CO2)—a 40 percent reduction of urban passenger transport emissions—could be eliminated by 2050 if the world expands public transportation, walking and cycling in cities, according to a new report released by the University of California, Davis, and the Institute for Transportation and Development Policy (ITDP).

Human papillomavirus (HPV) is one of the most common sexually transmitted infections. Up to 80% of sexually active women are infected at some point in their lives and infection with specific "high risk" strains of HPV has an established link to cervical cancer.

(September 16th, 2014; San Francisco) – In a healthcare climate where the costs of treatment are increasingly weighed against potential benefit, a Yale study has found that radiation oncologists are using fewer or less-aggressive radiation procedures on elderly women with early-stage breast cancer. The findings are scheduled to be presented at the 56th annual conference of the American Society for Radiation Oncology in San Francisco. (Abstract 131: Evaluating National Practice in Radiotherapy for Elderly Women: Response to a Randomized Trial and Cost Effectiveness on a National Scale.)

Magnesium sulfate given intravenously to pregnant women at risk of very preterm birth was not associated with benefit on neurological, behavioral, growth, or functional outcomes in their children at school age, according to a study in the September 17 issue of JAMA.

DETROIT – A new stereotactic radiosurgery system provides the same or a higher level of accuracy in targeting cancer tumors – but offers greater comfort to patients and the ability to treat multiple tumors at once – when compared to other radiation therapy stereotactic systems, according to researchers at Henry Ford Hospital in Detroit.

The study shows the Edge™ Radiosurgery Suite is able to target cancer tumors within 1 mm, providing sub-millimeter accuracy with extreme precision.

High school biology taught us that we inherit certain traits from our parents that are pre-determined. But what if you could change how these genes play out by taking certain drugs or better yet, just changing your diet? That's exactly what a team of researchers at the Boston University School of Medicine (BUSM) have proposed through their research of epigenetics research.

The same viruses that make us sick can take up residence in and on the human body without provoking a sneeze, cough or other troublesome symptom, according to new research at Washington University School of Medicine in St. Louis.

On average, healthy individuals carry about five types of viruses on their bodies, the researchers report online in BioMed Central Biology. The study is the first comprehensive analysis to describe the diversity of viruses in healthy people.

Men with prostate cancer may one day be able to predict when and how much various treatments will impact their urinary and sexual functioning, thanks in part to new findings that researchers at Fox Chase Cancer Center presented at the American Society for Radiation Oncology's 56th Annual Meeting on Tuesday, September 16.

In this issue of PLOS Medicine, Kathleen Holloway from WHO and David Henry (University of Toronto, Canada) evaluated data on reported adherence to WHO essential medicines practices and measures of quality use of medicines from 56 low and middle income countries for 2002-2008. They compared the countries' government-reported implementation of 36 essential medicines policies with independent survey results for 10 validated indicators of quality use of medicines (QUM).

The meteorite impact that spelled doom for the dinosaurs 66 million years ago decimated the evergreens among the flowering plants to a much greater extent than their deciduous peers, according to a study led by UA researchers. The results are published in the journal PLOS Biology.

This release is available in Japanese.

A University of Tokyo research group has discovered that pentatraxin 3 (PTX3), a protein that helps the innate immune system target invaders such as bacteria and viruses, can reduce mortality of mice suffering from sepsis. This discovery may lead to a therapy for sepsis, a major cause of death in developed countries that is fatal in one in four cases.

66 million years ago, a 10-km diameter chunk of rock hit the Yukatan peninsula near the site of the small town of Chicxulub with the force of 100 teratons of TNT. It left a crater more than 150 km across, and the resulting megatsunami, wildfires, global earthquakes and volcanism are widely accepted to have wiped out the dinosaurs and made way for the rise of the mammals. But what happened to the plants on which the dinosaurs fed?

We respond to infections in two fundamental ways. One, which has been the subject of intensive research over the years, is "resistance," where the body attacks the invading pathogen and reduces its numbers. Another, which is much less well understood, is "tolerance," where the body tries to minimise the damage done by the pathogen. Now an elegant study using data from a large Swiss cohort of HIV-infected individuals gives us a tantalising glimpse into why some people cope with HIV better than others.