In order to better communicate their procedure, Krause and her colleagues decided to publish with JoVE. "Because the reader can actually watch the process and see how reagents, instruments, and animals are physically handled over time, the likelihood of reproducing this method in their own labs is greatly enhanced," Krause said. "We believe this will help spread this new technical capability to many labs who are carrying out breast cancer research."
In this video, scientists demonstrate how to deliver drugs to the mammary gland via nipple-injection.
(Photo Credit: JoVE)
This is an example of gene-targeting in a mouse mammary gland using this technique. Here, a fluorescent gene-targeting substance was injected via the nipple duct, and is shown to have targeted an example gene, cyclophilin.
(Photo Credit: JoVE)