Earth
Bacterial Vaginosis (BV) is an infection affecting more than 20% of women worldwide. Caused by a change in the natural balance of the vaginal microbiota, this infection can lead to adverse outcomes in pregnancy as well as more susceptibility to sexually transmitted diseases such as HIV, herpes simplex virus, chlamydia, or gonorrhea. While previous studies strongly suggest that partners' reproductive microbiomes might be exchanged in BV, a question remained: is the penile microbiota at the origin of BV onset in women?
Artificial intelligence can increase the effectiveness of drug repositioning or repurposing research, according to a study published in Translational Psychiatry. In the study, which was supported by São Paulo Research Foundation - FAPESP, Brazilian researchers correlated information on genes associated with psychiatric and neurological disorders and drugs approved for use in treating other diseases that might potentially inhibit or activate these genes.
What The Study Did: This study uses 2018 data from the National Health and Aging Trends Study to assess how common it is for older adults in the United States to be unprepared to access video or telephone telemedicine because of disability or inexperience with technology.
Authors: Kenneth Lam, M.D., of the University of California, San Francisco, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
The tension in the outer membrane of cells plays an important role in a number of biological processes. A localised drop in tension, for example, makes it easier for the surface to be bending inward and form invaginations that will become free vesicles inside the cell. These are delimited by a membrane that contains all proteins originally present in the invaginations. A fundamental function of these so-called endosomes is to sort proteins to their cellular destination, e.g. reutilization or degradation. Are the functions of endosomes modulated by variations in tension?
The COVID-19 pandemic has led to a significant increase in video visits between patients and their doctors, but for many older adults, the shift has cut them off from care, rather than connecting them.
A study by researchers at UC San Francisco has found that more than a third of adults over age 65 face potential difficulties seeing their doctor via telemedicine, with the greatest challenges experienced by older, low-income men in remote or rural areas, especially those with disabilities or poor health. The findings appear online Aug. 3, 2020, in JAMA Internal Medicine.
Despite enormous efforts to advance traditional pharmacology approaches, more than three quarters of all human proteins remain beyond the reach of therapeutic development. Targeted protein degradation (TPD) is a novel approach that could overcome this and other limitations, and thus represents a promising therapeutic strategy. TPD is based on small molecules, generally called"degraders", which can eliminate disease-causing proteins by causing their destabilization.
Ithaca, NY--A half-century of controversy over two popular bird species may have finally come to an end. In one corner: the Bullock's Oriole, found in the western half of North America. In the other corner: the Baltimore Oriole, breeding in the eastern half. Where their ranges meet in the Great Plains, the two mix freely and produce apparently healthy hybrid offspring. But according to scientists from the Cornell Lab of Ornithology, hybridization is a dead end and both parent species will remain separate. Findings from the new study were published today in The Auk.
Traditional single-cell sequencing methods help to reveal insights about cellular differences and functions - but they do this with static snapshots only rather than time-lapse films. This limitation makes it difficult to draw conclusions about the dynamics of cell development and gene activity. The recently introduced method "RNA velocity" aims to reconstruct the developmental trajectory of a cell on a computational basis (leveraging ratios of unspliced and spliced transcripts). This method, however, is applicable to steady-state populations only.
“Recognizing and Treating COPD in Older Adults," the latest issue of the What’s Hot newsletter from The Gerontological Society of America, addresses what is known about the prevalence, incidence, and impact of chronic obstructive pulmonary disease (COPD) in older adults.
CHAMPAIGN, Ill. -- Compared with adults, children and adolescents are less sensitive to the sweet taste and need 40% more sucrose in a solution for them to detect the taste of sugar, a new study found.
Along with higher taste-detection thresholds, both children and adolescents prefer significantly more concentrated levels of sweetness than adults.
Dingoes have gotten around 6-9 per cent bigger over the past 80 years, new research from UNSW and the University of Sydney shows – but the growth is only happening in areas where poison baiting is used.
Encouraging paid workers to employ the 'right kind' of respectful personal relationship with young people with disability will lift standards in the sector, experts say.
With good quality relationships, children and young adults with cognitive disability feel "valued, respected and cared about" in their daily lives and, in turn, give carers more job satisfaction and self-respect, international researchers say in a new paper published in the international Disability & Society journal.
In some versions of the game blackjack, one way to win against the house is for players at the table to work as a team to keep track of and covertly communicate amongst each other the cards they have been dealt. With that knowledge, they can then estimate the cards still in the deck, and those most likely to be dealt out next, all to help each player decide how to place their bets, and as a team, gain an advantage over the dealer.
A current problem for a wide range of chemists is when stirring a solution in the laboratory there is a need to check the properties of the solution and monitor how they change.
In the paper, 'Monitoring chemistry in situ with the Smart Stirrer --a magnetic stirrer bar with an integrated process monitoring system' published in the journal ACS Sensors, researchers from the School of Engineering, the Mathematics Institute and WMG at the University of Warwick present their innovative stirrer sensor.
A research team led by Prof. SHANG Zhaohui from National Astronomical Observatories of the Chinese Academy of Sciences (NAOC) has proved that Dome A in Antarctica is the best site for optical astronomical observation on Earth. The study was published in Nature on July 29.