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New guidelines proposed by a group of international experts will help better study the prevalence and geography of counterfeit and other poor quality medicines that threaten public health across the world. The guidelines—called MEDQUARG, which stands for Medicine Quality Assessment Reporting Guidelines—are published in this week's open access journal PLoS Medicine.

  • Researchers used functional magnetic resonance imaging (fMRI) in a study to determine the neural mechanisms involved in financial decision-making under risk when a financial expert gives advice.
  • Study findings show that expert advice suppresses areas of the brain responsible for making value judgments. Conversely, those regions of the brain show activity when outside advice is not involved in the decision-making process.

Coenzyme F420, a small molecule that helps certain enzymes transfer electrons, is found in microorganisms known as methane-producing archaea, some of which thrive in extreme environments. It also helps the bacterium that causes tuberculosis (TB) to survive the defenses of the human immune system. Scientists have now discovered at least one way F420 helps to arm the pathogen.

PASADENA, Calif.--A tiny genetic mutation is the key to understanding why nicotine--which binds to brain receptors with such addictive potency--is virtually powerless in muscle cells that are studded with the same type of receptor. That's according to California Institute of Technology (Caltech) researchers, who report their findings in the March 26 issue of the journal Nature.

INDIANAPOLIS – Same-day medical scheduling, also known as on demand scheduling, does not improve care of chronically ill individuals, according to a study of 4,060 adult patients with diabetes.

DALLAS – March 20, 2009 – A new study by UT Southwestern Medical Center researchers is the first to pinpoint damage inside the brains of veterans suffering from Gulf War syndrome – a finding that links the illness to chemical exposures and may lead to diagnostic tests and treatments.

ANN ARBOR, Mich.---You're sitting at your desk and suddenly your heart is beating in overdrive or worse, lurching along like a car on fumes. It is a shocking, uncomfortable and frightening sensation.

Irregular heart rhythms are a common cause of sudden cardiac death or SCD, a condition that accounts for 450,000 deaths annually in the United States. Scientists are now closer to understanding what causes SCD and who it may strike, said Gonçalo Abecasis, associate professor of biostatistics at the University of Michigan School of Public Health.

SALT LAKE CITY, March 23, 2009 – In a dramatic rewrite of the recipe for life, scientists from Florida today described the design of a new type of DNA with 12 chemical letters instead of the usual four. Presented here at the ACS meeting in Salt Lake City, this artificial genetic system could help to usher in the era of personalized medicine for millions of patients with HIV, hepatitis and other diseases.

SALT LAKE CITY, March 23, 2009 — In the future, natural gas derived from chunks of ice that workers collect from beneath the ocean floor and beneath the arctic permafrost may fuel cars, heat homes, and power factories. Government researchers are reporting that these so-called "gas hydrates," a frozen form of natural gas that bursts into flames at the touch of a match, show increasing promise as an abundant, untapped source of clean, sustainable energy.

SALT LAKE CITY, March 23, 2009 — Researchers are reporting compelling new scientific evidence for the existence of low-energy nuclear reactions (LENR), the process once called "cold fusion" that may promise a new source of energy. One group of scientists, for instance, describes what it terms the first clear visual evidence that LENR devices can produce neutrons, subatomic particles that scientists view as tell-tale signs that nuclear reactions are occurring.

From spilling a cup of coffee to failing to notice a stop sign, everyone makes an occasional error due to lack of attention. Now a team led by a researcher at the University of California, Davis, in collaboration with the Donders Institute in the Netherlands, has found a distinct electric signature in the brain which predicts that such an error is about to be made.

In the first observation if its kind, scientists at the Weizmann Institute of Science and San Diego State University were able to watch what happens when a star the size of 50 suns explodes. As they continued to track the spectacular event, they found that most of the star's mass collapsed in on itself, resulting in a large black hole.

Stroke can impair balance, heightening the risk of a debilitating fall. But a University of Illinois at Chicago researcher has found that stroke survivors can improve their balance by practicing the Chinese martial art of tai chi.

Christina Hui-Chan, professor and head of physical therapy at UIC, has studied and used tai chi as a way to improve balance and minimize falls among healthy elderly subjects. Now she and a colleague have seen similar results in a group of stroke survivors.

Using what they say is a relatively simple method, scientists at Georgetown University Medical Center have extracted stem/progenitor cells from adult testes and have converted them back into pluripotent embryonic-like stem cells. Researchers say that the naïve cells are now potentially capable of morphing into any cell type that a body needs, from brain neurons to pancreatic tissue.

African Americans have a shorter life expectancy than whites. A new study finds that for most types of cancer, the disparity in mortality is almost entirely due to the fact that African Americans are more likely to get cancer in the first place.

A new UCLA study, published in Journal of General Internal Medicine, says that for most types of cancer, their stage at presentation and survival after diagnosis play a much smaller role.