Earth

Progressive vision loss, and eventually blindness, are the hallmarks of juvenile neuronal ceroid lipofuscinosis (JNCL) or CLN3-Batten disease. New research shows how the mutation associated with the disease could potentially lead to degeneration of light sensing photoreceptor cells in the retina, and subsequent vision loss.

People living in regions with high levels of outdoor artificial light at night may face a higher risk of developing thyroid cancer. The finding comes from a study published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

Researchers from Kumamoto University (Japan) have clarified the mechanism by which blood and lymph vessels remain segregated from one another after development. The characteristics and structures of these two vessel types are very similar, and how they maintain separation has remained unexplained for many years. In this study, researchers found that the molecule Folliculin (FLCN) in vascular endothelial cells acts as a gatekeeper to maintain that separation.

A new study in Frontiers in Marine Science provides a first-of-its-kind evaluation of which regions of southern European seas are in the most need of fishing restrictions. These areas have persistently shown high numbers of undersized fish and crustaceans, which are typically discarded because they are below the allowable size limit for collection. These findings may offer a strategy for prioritizing conservation efforts and ensuring more sustainable fishery management in the future.

At the time of writing, coronavirus disease 2019 (COVID-19) is seriously threatening human lives and health throughout the world. Before effective vaccines and specific drugs are developed, non-pharmacological interventions and numerical model predictions are essential. To this end, a group led by Professor Jianping Huang from Lanzhou University, China, developed the Global Prediction System of the COVID-19 Pandemic (GPCP).

PROVIDENCE, R.I. [Brown University] -- A new technique developed by Brown University researchers reveals the forces involved at the cellular level during biological tissue formation and growth processes. The technique could be useful in better understanding how these processes work, and in studying how they may respond to environmental toxins or drug therapies.

A study from the Center for Phage Technology, part of Texas A&M's College of Agriculture and Life Sciences and Texas A&M AgriLife Research, shows how the "hidden" genes in bacteriophages -- types of viruses that infect and destroy bacteria -- may be key to the development of a new class of antibiotics for human health.

The study has been published in Nature Communications and Current Science Daily, as well as featured in a recent Nature Research Microbiology Community blog post.

Primeval forests are of great importance for biodiversity and global carbon and water cycling. The three-dimensional structure of forests plays an important role here because it influences processes of gas and energy exchange with the atmosphere, whilst also providing habitats for numerous species. An international research team led by the University of Göttingen has investigated the variety of different complex structures that can be found in the world's forests, as well as the factors that explain this diversity. The results have been published in Nature Communications.

This is the finding of an 18-year-study of over 300,000 people with diabetes in England, from scientists from Imperial College London and published in the journal The Lancet Diabetes & Endocrinology.

Thursday Feb 4th is World Cancer Day.

The research, funded by the Wellcome Trust, reveals that between 2001-2018 heart disease and stroke were no longer the leading causes of death among people with diabetes, as they were 18 years ago.

Researchers at Flinders University are working to remedy this situation by identifying what triggers this chronic pain in the female reproductive tract.

Dr Joel Castro Kraftchenko - Head of Endometriosis Research for the Visceral Pain Group (VIPER), with the College of Medicine and Public Health at Flinders University - is leading research into the pain attached to Dyspareunia, also known as vaginal hyperalgesia or painful intercourse, which is one of the most debilitating symptoms experienced by women with endometriosis and vulvodynia.

New tools and methods have been described by WEHI researchers to study an unusual protein modification and gain fresh insights into its roles in human health and disease.

The study - about how certain sugars modify proteins - was published today in Nature Chemical Biology. Led by WEHI researcher Associate Professor Ethan Goddard-Borger, this work lays a foundation for better understanding diseases like muscular dystrophy and cancer.

At a glance

In order to produce tiny electronic memories or sensors in future, it is essential to be able to arrange individual metal atoms on an insulating layer. Scientists at Bielefeld University's Faculty of Chemistry have now demonstrated that this is possible at room temperature: molecules of the metal-containing compound molybdenum acetate form an ordered structure on the insulator calcite without jumping to other positions or rotating. Their findings have been presented in the Nature Communications journal.

Cardiac patients who also have diabetes will be able to do their rehabilitation exercises more safely, thanks to the world's first guidance on the subject, which has been published by international experts including a Swansea University academic.

The guidance will be a crucial resource for healthcare professionals, so they can help the growing number of cardiac rehabilitation patients who also have diabetes.

Between chemistry classes, gemstones, and electronics, the idea of crystals, substances with an ordered and periodic arrangement of atoms is quite common. But about 40 years ago, a strange particle was discovered by scientists that hasn't become commonplace in our world yet: quasicrystals. These are structures with curious atomic arrangements, which, while superficially similar to crystals, lack periodicity despite being ordered.

In order to fight pathogens, mast cells regulate inflammatory reactions of the immune system. Both mast cells and neutrophils are white blood cells and are critical for the body's immune defense. A team of scientists around the immunologist Prof. Dr. Anne Dudeck and the bioengineer Jan Dudeck has discovered a crucial aspect of the communication between mast cells and neutrophils. These new findings may allow for developing innovative, targeted therapeutic strategies to dampen allergic responses and inflammatory reactions.