Culture

Schizophrenia is a potentially debilitating mental illness affecting a person's thought processes, perception, language and sense of oneself. Globally, 7 out of every 1000 are affected, accounting for 24 million patients. Significant risk factors for the illness in males is serious problems during birth or fetal hypoxia while increased cerebral ventricular size in both infancy and adulthood due to embryological defects can underlie the condition in other patients.

Philadelphia, PA, September 20, 2013 – A new study reports that countries with lower gun ownership are safer than those with higher gun ownership, debunking the widely quoted hypothesis that guns make a nation safer. Researchers evaluated the possible associations between gun ownership rates, mental illness, and the risk of firearm-related death by studying the data for 27 developed countries. Their findings are published in the current issue of The American Journal of Medicine.

Scientists know that physical and biochemical signals can guide cells to make, for example, muscle, blood vessels or bone. But the exact recipes to produce the desired tissues have proved elusive.

Now, researchers at Case Western Reserve University have taken a step toward identifying that mix by developing an easy and versatile way of forming physical and biochemical gradients in three dimensions.

Ultimately, one of their goals is to engineer systems to manipulate stem cells to repair or replace damaged tissues and organs.

New research from Johns Hopkins suggests that it may not be the steroids in spinal shots that provide relief from lower back pain, but the mere introduction of any of a number of fluids, such as anesthetics and saline, to the space around the spinal cord.

Persons with alcohol and other drug dependence who received chronic care management including relapse prevention counseling and medical, addiction and psychiatric treatment were no more abstinent than those who received usual primary care, according to a study in the September 18 issue of JAMA.

"Emergency department (ED) use has been affected by insurance patterns over time and will likely be further affected by expansions of coverage from health care reform." Uninsured patients are often thought of as high and frequently inappropriate ED users, but insured patients, particularly those with Medicaid coverage, may have difficulties accessing primary care and may rely on EDs more frequently than uninsured patients, write Renee Y. Hsia, M.D., M.Sc., of the University of California, San Francisco, and colleagues.

WASHINGTON, DC — A preclinical study led by researchers at Children's National Medical Center has found that a new oral drug shows early promise for the treatment of Duchenne muscular dystrophy (DMD). The results, published in EMBO Molecular Medicine, show that the drug, VBP15, decreases inflammation and protects and strengthens muscle without the harsh side effects linked to current treatments with glucocorticoids such as prednisone.

(Edmonton) Researchers at the University of Alberta have developed a synthetic peptide that could be the first in a new class of drugs to treat heart disease, high blood pressure and diabetes.

Researchers at the U of A found that a deficiency in the peptide apelin is associated with heart failure, pulmonary hypertension and diabetes. They also developed a synthetic version that targets pathways in the heart and promotes blood vessel growth.

DETROIT – Heart patients' mental state and thinking abilities may help predict whether costly and potentially dangerous early hospital readmission will follow their release after treatment, according to the results of a significant new study by Henry Ford Hospital researchers.

The findings have important implications for the health care industry as it struggles to contain unnecessary costs, according to the study's lead author, Mark W. Ketterer, Ph.D., a psychologist and administrator for Henry Ford.

The study is published online in Psychosomatics.

The National Heart Centre Singapore (NHCS) research team has successfully and completely reversed the effects of the hERG (human ether-a-go-go-related gene) mutation in long QT syndrome 2 (LQTS 2) in patient-specific heart cells, scoring a world's first. Long QT syndrome 2 is a dangerous heart rhythm disorder that can lead to sudden cardiac death, even in young patients. It is caused by a mutation in a specific gene known as hERG, which helps to control the electrical activity in the heart cells and coordinate its beating rhythm.

More children than ever before are living with a debilitating digestive disease, research has shown.

Scientists have found that coeliac disease affects six times more children living in Scotland now than it did in 1990.

A team from the University of Edinburgh and Queen Margaret University analysed the health records of children from South East Scotland aged under 16 years who were newly diagnosed with the condition between 1990 and 2009.

Using a simple survey tool, a team of researchers has done what complex studies have failed to do -- provide data that identifies starting points for preventing diarrheal disease outbreaks in at least one region of Africa.

Diarrheal illness is a leading cause of disease and death in children under 5, and in HIV-plagued Botswana, it is a significant issue for those over 5 as well.

Raleigh-Durham, NC. -- A new meta-analysis of 29 randomized studies involving more than 4,500 patients with knee osteoarthritis (OA) found that intra-articular hyaluronic acid (HA) injections provided significant improvement in pain and function compared to saline injections.

The first of its kind, the review showed 461 cases of links between racism and child and youth health outcomes.

Lead researcher Dr Naomi Priest at the McCaughey VicHealth Centre for Community Wellbeing at the University of Melbourne said the review demonstrated racism as an important factor influencing the health and wellbeing of children and youth.

TORONTO, September 17, 2013 – A review study published today finds that financial incentives –as modest as $5 per week – can increase the amount of exercise people do.

Lead author Marc Mitchell, University of Toronto PhD candidate and Cardiac Rehabilitation Supervisor at Toronto Rehab, worked under the leadership of University of Toronto exercise psychologist Guy Faulkner and exercise physiologist Jack Goodman to publish these findings in the September online publication of the American Journal of Preventive Medicine.

The review study looked at 1,500 patients.