Artificial sweeteners, promoted as aids to weight loss and diabetes prevention, could actually hasten the development of glucose intolerance and metabolic disease; and they do it in a surprising way: by changing the composition and function of the gut microbiota – the substantial population of bacteria residing in our intestines. These findings, the results of experiments in mice and humans, were published today in Nature. Among other things, says Dr. Eran Elinav of the Weizmann Institute's Immunology Department, who led this research together with Prof.
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COLUMBUS, Ohio – Mathematics might be able to reduce the need for invasive biopsies in patients suffering kidney damage related to the autoimmune disease lupus.
In a new study, researchers developed a math model that can predict the progression from nephritis – kidney inflammation – to interstitial fibrosis, scarring in the kidney that current treatments cannot reverse. A kidney biopsy is the only existing way to reach a definitive diagnosis of the damage and its extent.
A new study gives a blow-by-blow account of injuries inflicted on King Richard III's body at the Battle of Bosworth Field on 22 August, 1485.
Modern forensic analysis of the King’s skeletal remains reveals that three of his injuries had the potential to cause death quickly- two to the skull (pictured top left) and one to the pelvis (pictured bottom right).
WASHINGTON -- The U.S. health care system is not properly designed to meet the needs of patients nearing the end of life and those of their families, and major changes to the system are necessary, says a new report from the Institute of Medicine. The 21-member committee that wrote the report envisioned an approach to end-of-life care that integrates traditional medical care and social services and that is high-quality, affordable, and sustainable.
CHICAGO --- The first blood test to diagnose major depression in adults has been developed by Northwestern Medicine® scientists, a breakthrough approach that provides the first objective, scientific diagnosis for depression. The test identifies depression by measuring the levels of nine RNA blood markers. RNA molecules are the messengers that interpret the DNA genetic code and carry out its instructions.
Campaigns against disposable plastic shopping bags recently scored a major win. In August, California lawmakers passed the first statewide ban on the bags, and Governor Jerry Brown is expected to sign it. But the plastic bag industry is not yielding without a fight, according to an article in Chemical & Engineering News.
A mathematical model that replicates Ebola outbreaks can no longer be used to ascertain the eventual scale of the current epidemic, finds research conducted by the University of Warwick.
Dr Thomas House, of the University's Warwick Mathematics Institute, developed a model that incorporated data from past outbreaks that successfully replicated their eventual scale.
New research presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria, shows that people suffering from diabetic peripheral neuropathy (DPN)—a complication of diabetes that affects the nerves in the limbs—are likely to sway more during stair climbing, and thus are more likely to fall. Steven Brown, Manchester Metropolitan University, UK, is the lead author on this research, which has been conducted by researchers at Manchester Metropolitan University and the University of Manchester, UK.
A study of more than 18,000 patients with type 1 diabetes has shown that use of insulin pumps to administer insulin rather than treatment with multiple daily insulin injections results in a 29% reduction in all-cause mortality and 43% reduction in the risk of fatal cardiovascular disease (CVD, i.e. coronary heart disease or stroke). The study is presented at the annual meeting of the European Association for the Study of Diabetes in Vienna, Austria, and was prepared by Dr Soffia Gudbjörnsdottir, University of Gothenburg, Sweden and colleagues.
The prevalence of abdominal obesity and average waist circumference increased among U.S. adults from 1999 to 2012, according to a study in the September 17 issue of JAMA.
Waist circumference is a simple measure of total and intra-abdominal body fat. Although the prevalence of abdominal obesity has increased in the United States through 2008, its trend in recent years has not been known, according to background information in the article.
Among older adults with chronic obstructive pulmonary disease (COPD), particularly those with asthma, newly prescribed long-acting beta-agonists (LABAs) and inhaled corticosteroid combination therapy, compared with newly prescribed LABAs alone, was associated with a lower risk of death or COPD hospitalization, according to a study in the September 17 issue of JAMA.
In an analysis of the results of nearly 50 randomized trials that examined treatments of venous thromboembolisms (blood clot in a vein), there were no significant differences in clinical and safety outcomes associated with most treatment strategies when compared with the low-molecular-weight heparin-vitamin K antagonist combination, according to a study in the September 17 issue of JAMA.
Ottawa – September 16, 2014 – Physicians around the world now have guidance that can help them determine the best oral blood thinners to use for their patients suffering from blood clots in their veins, thanks to a patient of The Ottawa Hospital who asked his physician a question he couldn't answer. This new guidance is found in a study published today by JAMA, the Journal of the American Medical Association.
WASHINGTON, DC – September 16, 2014 – The first randomized trial to examine serial optical coherence tomography (OCT) in primary percutaneous coronary intervention (PCI) was reported at the 26th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Sponsored by the Cardiovascular Research Foundation (CRF), TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine.
WASHINGTON, DC – September 14, 2014 – A new study found that fractional flow reserve (FFR)-guided provisional side branch (SB) stenting of true coronary bifurcation lesions yields similar outcomes to the current standard of care. The DKCRUSH-VI clinical trial is the first study to compare FFR-guided and angiography-guided stenting.