WASHINGTON - Potentially useful biomarker tests for molecularly targeted therapies are not being adopted appropriately into clinical practice because of a lack of common evidentiary standards necessary for regulatory, reimbursement, and treatment decisions, says a new report by the National Academies of Sciences, Engineering, and Medicine.
Culture
Long-term exercise appears to be beneficial for Spinal Muscular Atrophy (SMA) like mice, suggesting a potential of active physiotherapy for patient care; according to a study published today in the Journal of Physiology.
TAMPA, Fla. (March 4, 2016) - Glioblastoma multiforme (GBM) is a highly aggressive brain tumor with low survival rates, with newly diagnosed patients surviving a median of 14 months and recurrent patients surviving a median of only 3 to 9 months. New therapeutic targets and biomarkers for prognosis are urgently needed. Moffitt Cancer Center researchers recently reported that expression of the protein BIRC3 is associated with poor survival and recurrent disease in GBM patients; and therefore may be a good therapeutic target.
The decline in the fluidity, or dynamism, of the U.S. labor market has been occurring along a number of dimensions -- including the rate of job-to-job transition, hires and separations, and geographic movement across labor markets -- since at least the 1980s, and these declines are all related, according to a new paper to be presented next week at the Brookings Panel on Economic Activity.
Research presented at the 2016 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) challenges two common rehabilitation standards: physical therapy following total hip replacement (THR) at an outpatient facility, and gradual movement of the quadriceps tendon following total knee replacement (TKR) surgery.
ORLANDO, Fla.--Many orthopaedic patients are eager to track and improve their health and progress before, during and after treatment. A digital fitness device, technology already owned by 1 in 10 Americans, provides a unique opportunity for patients to monitor their activity levels, medication use, weight, sleep patterns, rehabilitation progress, and other personal health data, ultimately empowering them to improve clinical outcomes, according to a study presented today at the 2016 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).
ORLANDO, Fla.--The use of opioids (narcotic pain medication), often prescribed for chronic musculoskeletal pain, has skyrocketed in recent years with 98 percent of the world's opioid prescriptions filled in North America. Two research studies presented this week at the 2016 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), link decreased opioid use prior to joint replacement surgery with improved patient satisfaction and outcomes, fewer complications, and a reduced need for post-surgical opioids.
ORLANDO, Fla.-- Orthopaedic care for patients living in remote areas may be managed through phone or email, allowing patients to receive treatment without travelling to a larger, urban hospital for care, according to a study presented today at the 2016 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). The study also found that remote care may provide significant savings in time, missed work, and health care and transportation costs for residents living in rural areas.
If all patients scheduled for knee replacement were directed to high-volume hospitals for the surgery, it could save the U.S. healthcare system between $2.5 and $4 billion annually by the year 2030, according to a study at Hospital for Special Surgery (HSS) in New York City.
Around one in seven 11 years olds in the UK have had at least one drink of alcohol, according to a study published in the open access journal BMC Public Health, which analyzed data from 10,498 children aged 11.
The study, by researchers from University College London and the London School of Economics and Political Science, is the first to examine drinking behaviors in very early adolescence in relation to a wide range of factors that are associated with alcohol consumption in children, such as family, friends and the young person's views about alcohol.
European consumer research1 conducted by the Institute for Scientific Information on Coffee (ISIC) to better understand beliefs, behaviours, and knowledge regarding coffee and a healthy diet, suggests consumers are confused about the potential health benefits of coffee, in part because the information they are receiving is not always in line with the latest science.
Reported dog attacks on guide dogs have risen significantly over a five year period, finds a study published online in the journal Veterinary Record.
A total of 629 attacks were reported between 2010 and 2015, with an increase from an average of three per month in 2010 to eleven attacks per month in 2015. The authors say it is not clear whether this reflects higher levels of reporting or a real trend.
Continuous positive airway pressure, or CPAP, appears to improve glycemic control in patients with obstructive sleep apnea (OSA) and type 2 diabetes that is not well controlled, according to research published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. "Effect of CPAP on glycemic control in patients with obstructive sleep apnea and type 2 diabetes: A randomized clinical trial," is believed to be the first randomized controlled trial of its kind.
LAWRENCE -- Mainstream political parties in Europe have failed to respond to the increasing public skepticism of the European Union, opening the door for nationalist political groups to gain more power, a University of Kansas researcher has found.
The fallout of the financial crisis and subsequent bailouts of Greece and other struggling nations, coupled with the recent migration crisis, have further enflamed skepticism toward European integration, said Robert Rohrschneider, KU's Sir Robert Worcester Distinguished Professor of Political Science.
When we think of language, we usually think of words, phrases, and sentences--strings of abstract symbols. In research over the past 50 years, cognitive and social scientists have developed extensive accounts of how people communicate with these symbols. But when people are face to face, they also communicate with actions that depict people, objects, and events. They create these depictions with their hands, arms, head, face, voice, and entire body, sometimes with other props but often without.