Researchers have uncovered a metabolic defect that spurs T cells to go rogue in rheumatoid arthritis patients. The findings suggest that prooxidants, chemicals that generate reactive oxygen species (ROS), rather than antioxidants that protect against ROS, may help fix this metabolic malfunction and quell joint inflammation. Rheumatoid arthritis is a common autoimmune disease in which overactive T cells trigger joint damage and inflammation.
Culture
A new drug to treat the muscle wasting disease inclusion body myositis (IBM) reverses key symptoms in mice and is safe and well-tolerated in patients, finds a new study led by the Medical Research Council (MRC) Centre for Neuromuscular Diseases at University College London (UCL) and the University of Kansas Medical Center.
Washington, DC--To provide integrated care for people who have diabetes and may be at risk of developing related medical complications, the U.S. health care system needs to continue building effective multidisciplinary care team models, according to new recommendations issued by the Endocrine Society today.
The Endocrine Society's analysis of the challenges and opportunities created by the Affordable Care Act's (ACA) implementation was published online today in the Journal of Clinical Endocrinology & Metabolism.
Ann Arbor, MI, March 23, 2016 - Sedentary behavior, particularly sitting, has recently become a prevalent public health topic and target for intervention. As work and leisure activities shift from standing to sitting, increased sitting time is starting taking a toll on our bodies. A new study in the American Journal of Preventive Medicine found that sitting for more than three hours per day is responsible for 3.8% of all-cause mortality deaths.
Longer-time to follow-up with patients after heart attack associated with worse medication adherence
In a study published online by JAMA Cardiology, Tracy Y. Wang, M.D., M.H.S., M.Sc., of Duke Clinical Research Institute, Durham, N.C., and colleagues examined whether earlier outpatient follow-up after acute myocardial infarction (AMI; heart attack) is associated with higher rates of medication adherence.
Aalto University researchers found that the emotional impact experienced by music listeners depends on the concert hall's acoustics.
A recent review of the medical literature does not support the use of antipsychotic medications for preventing or treating delirium in hospitalized patients.
Commonly used antidepressants, known as selective serotonin reuptake inhibitors, are not associated with an increased risk of cardiovascular conditions, such as heart attacks and strokes in people aged below 65, finds a study published in The BMJ today.
Depression is known to increase the risk of cardiovascular outcomes, but whether antidepressants, particularly selective serotonin reuptake inhibitors, increase or reduce this risk remains controversial.
In The BMJ this week, two experts debate whether doctors should boycott working in Australia's immigration detention centres.
Dr David Berger at Broome Hospital in Western Australia, argues that however compassionate their intentions, "doctors who treat people who have been tortured and then acquiesce in the continuation of torture themselves are supporting torture."
Commonly used antidepressants, known as 'selective serotonin reuptake inhibitors', are not associated with an increased risk of cardiovascular conditions, such as heart attacks and strokes, according to new research at The University of Nottingham.
Depression is known to increase the risk of cardiovascular problems, but whether antidepressants, particularly SSRIs, increase or reduce this risk remains controversial.
The cost of treating hepatitis C virus (HCV) could be cut up to 50 percent if mathematical models are used to predict when patients can safely stop taking direct-acting antiviral (DAA) medication, according to a new study by researchers at Loyola University Health System and Loyola University Chicago.
An estimated 170 million people have the blood-borne infection worldwide, which is a major cause of chronic liver disease. The recent approval of DAAs has led to a revolution in the treatment of HCV, but the high cost of DAAs limits access to treatment in America and abroad.
The mandatory reporting of female genital mutilation (FGM) as child abuse may not be the most appropriate first measure to reduce FGM in the UK and instead a multifaceted approach of training health workers, educating at-risk woman about FGM and incorporating mandatory screening for FGM risk factors during antenatal care may be more effective according to Maria Luisa Amasanti, from the Royal Free London NHS Foundation Trust, UK, and colleagues in an Essay published in this week's PLOS Medicine.
WASHINGTON --When older adults in severely debilitated states show up for treatment in the emergency department, emergency physicians and staff must be able to identify and document their symptoms and decide whether to report their concerns to adult protective services. This is a difficult decision as the patient's symptoms may stem from willful neglect, unintentional neglect or sub-acute symptoms caused by an underlying illness than manifest as neglect.
Xbox Kinects could be used in the future to assess the health of patients with conditions such as cystic fibrosis.
Normally found in the hands of gamers rather than medics the Microsoft sensors could be used to assess the respiratory function of patients.
Among adults with chronic low back pain, both mindfulness-based stress reduction and cognitive behavioral therapy resulted in greater improvement in back pain and functional limitations when compared with usual care, according to a study appearing in the March 22/29 issue of JAMA.