Technologies that make it harder for people to abuse opioids - like doctoring pills so that they produce unpleasant side effects if broken, crushed or injected -- likely will have limited effectiveness in stemming the global epidemic of opioid abuse, according to Adam Kaye, a professor of pharmacy at University of the Pacific.
Writing in the latest issue of the journal Current Pain and Headache Reports, Kaye and his co-authors argue that such technologies are no substitute for education.
Brivaracetam (trade name: Briviact) has been approved since January 2016 as add-on therapy for adolescents from the age of 16 years and adults with epileptic seizures. The German Institute for Quality and Efficiency in Health Care (IQWiG) now examined in an early benefit assessment whether this drug offers an added benefit for patients in comparison with the appropriate comparator therapy.
Vismodegib (trade name: Erivedge) has already been approved since 2013 for the treatment of patients with locally advanced basal cell carcinoma (BCC) or symptomatic metastatic BCC and has already undergone an early benefit assessment according to the Act on the Reform of the Market for Medicinal Products (AMNOG). The Federal Joint Committee (G-BA) limited its decision in February 2014 to two years, which is why the drug manufacturer now submitted a new dossier.
In a recent study of patients with overactive bladder (OAB), a 30 mg extended release formulation of propiverine hydrochloride was at least as effective and safe as a 4 mg extended release formulation of tolterodine tartrate. Both medications are called antimuscarinic drugs that block certain cell receptors, but propiverine differs from other antimuscarinics because of a dual mode of action.
Dining in dimly lit restaurants has been linked to eating slowly and ultimately eating less than in brighter restaurants, but does lighting also impact how healthfully we order?
Amsterdam, The Netherlands, May 26, 2016 - New research has found that the rise in alcohol-related mortality during the 1990s and early 2000s in Scotland, and the subsequent decline, were likely to be explained in part by increasing then decreasing alcohol affordability. The research was undertaken to understand better what the independent impact of the Scottish Government's alcohol strategy was.
(Washington, May 26, 2016)--The American College of Physicians (ACP) along with the American Academy of Family Physicians (AAFP), the American Academy of Pediatrics (AAP) and the American Congress of Obstetricians and Gynecologists (ACOG) sent a letter today to House and Senate leaders urging them to immediately pass legislation that would provide the highest possible funding level for research, prevention, control, and treatment of illnesses associated with the Zika virus that is commensurate with the public health emergency that the virus represents.
AURORA, Colo. (May 26, 2016) - A team of researchers at the University of Colorado School of Medicine and the VA Eastern Colorado Health Care System recently surveyed patients to understand barriers to reducing the use of opioids to manage chronic pain. The results of those interviews are published in the current issue of the journal Pain Medicine.
Anyone who's ever covered a wall with sticky notes to clearly map all of the steps in a process knows how valuable that exercise can be. It can streamline workflow, increase efficiency and improve the overall quality of the end result. Now, a public-private team led by the National Institute of Standards and Technology (NIST) has created a new international standard that can "map" the critically important environmental aspects of manufacturing processes, leading to significant improvements in sustainability while keeping a product's life cycle low cost and efficient.
WASHINGTON, D.C., May 25, 2016 -- Researchers at UCLA's Voice Center for Medicine and the Arts have recently examined the speech patterns of Hillary Clinton, Bernie Sanders, Donald Trump and Carly Fiorina in a variety of settings to determine whether the presidential candidates followed the same voice modulation strategies. They researchers found that despite the politicians' varied messages, their vocal delivery remains the same.
WASHINGTON, DC, May 23, 2016 -- The view that the rich are highly mobile has gained much political traction in recent years and has become a central argument in debates about whether there should be "millionaire taxes" on top-income earners. But a new study dispels the common myth about the propensity of millionaires in the United States to move from high to low tax states.
If you have three or more siblings, odds are that you have at least one year less of education than someone who has no siblings.
More kids in your family. Less education. This pattern isn't new, but a team of researchers led by BYU sociology professor Ben Gibbs studied why that educational dip occurs and found that there are exceptions to the trend. One group that is a major outlier is Mormons.
CINCINNATI--A person is admitted to the hospital with a stroke, but not much is known about whether or not that patient will undergo neuroimaging.
A team led by Achala Vagal, MD, associate professor at the University of Cincinnati (UC) College of Medicine and a UC Health radiologist, wanted to see whether differences in race, sex and/or age mattered when it came to neuroimaging use, and these findings, which showed a difference for young patients, men and African-Americans, will be presented at the American Society of Neuroradiology's annual meeting May 25 in Washington, DC.
A new study that examined timing and risk factors for suicide attempts by U.S. Army-enlisted soldiers suggests risks were highest among those soldiers never deployed and that never-deployed soldiers were at greatest risk in the second month of service, according to an article published online by JAMA Psychiatry.
Just like suicides, suicide attempts have increased in the U.S. Army over the past decade. But suicide attempts have been studied less despite their importance as a gateway to suicide.
Initiating antiretroviral therapy (ART) soon after diagnosis of an HIV infection did not prevent the progression of significant arterial inflammation in a small group of previously untreated patients. The findings from a Massachusetts General Hospital (MGH)-based research team suggest that ART alone is not sufficient to reduce the elevated arterial inflammation that appears to contribute to the increased risk of cardiovascular disease in HIV-infected individuals.