Culture
Writing in the January 3 issue of Cancer Cell, researchers at University of California San Diego School of Medicine report that detection of "copy editing" by a stem cell enzyme called ADAR1, which is active in more than 20 tumor types, may provide a kind of molecular radar for early detection of malignancies and represent a new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation.
RENO, Nev. - Winter snows are accumulating in the Sierra Nevada Mountains, creating the snowpacks that serve as a primary source of water for the western U.S.
University of Arizona biomedical engineering professor Philipp Gutruf is first author on the paper Fully implantable, optoelectronic systems for battery-free, multimodal operation in neuroscience research, published in Nature Electronics.
CORVALLIS, Ore. - A higher intake of vitamin C is crucial for metabolic syndrome patients trying to halt a potentially deadly cycle of antioxidant disruption and health-related problems, an Oregon State University researcher says.
That's important news for the estimated 35 percent of the U.S. adult population that suffers from the syndrome.
Boston, MA - Medicare's randomized trial of a new bundled payment model for hip and knee replacement surgeries led to $812 in savings per procedure, or a 3.1% reduction in costs, when compared with traditional means of paying for care, according to new research from Harvard T.H. Chan School of Public Health and Harvard Medical School. The study found that the bundled payment model was also associated with a reduction in use of skilled nursing care after the hospitalization, but had no effects on complication rates among patients.
There is no compelling evidence to indicate important health benefits of non-sugar sweeteners, and potential harms cannot be ruled out, suggests a review of published studies in The BMJ today.
Growing concerns about health and quality of life have encouraged many people to adopt healthier lifestyles and avoid foods rich in sugars, salt, or fat. Foods and drinks containing non-sugar sweeteners rather than regular ("free") sugars have therefore become increasingly popular.
Research suggests a specific treatment for Homozygous Familial Hypercholesterolaemic (HoFH) pateints; a combination therapy with PCSK9-inhibitors (PCSK9-I) and lipoprotein-apheresis (LA) may have synergistic effects on circulating lipid and lipoprotein levels. The relationship with the treatment regimen mentioned above can be investigated further with larger datasets.
Researchers have identified a group of genes that induces differences in the developing brains of male and female roundworms and triggers the initiation of puberty, a genetic pathway that may have the same function in controlling the timing of sexual maturation in humans.
The study, led by Columbia University scientists, offers new evidence for direct genetic effects in sex-based differences in neural development and provides a foundation to attempt to understand how men's and women's brains are wired and how they work.
CAMBRIDGE, MA -- Researchers from MIT and elsewhere have recorded, for the first time, the "temporal coherence" of a graphene qubit -- meaning how long it can maintain a special state that allows it to represent two logical states simultaneously. The demonstration, which used a new kind of graphene-based qubit, represents a critical step forward for practical quantum computing, the researchers say.
A ground-breaking new study led by researchers from the Lady Davis Institute (LDI) at the Jewish General Hospital (JGH) has succeeded in compiling an atlas of genetic factors associated with estimated bone mineral density (BMD), one of the most clinically relevant factors in diagnosing osteoporosis. The paper, published in Nature Genetics, identifies 518 genome-wide loci, of which 301 are newly discovered, that explain 20% of the genetic variance associated with osteoporosis.
CHAMPAIGN, Ill. -- By enticing away the repressors dampening unexpressed, silent genes in Streptomyces bacteria, researchers at the University of Illinois have unlocked several large gene clusters for new natural products, according to a study published in the journal Nature Chemical Biology.
According to the National Cancer Institute, patients diagnosed with non-small cell lung cancer (NSCLC) between the years 1995 and 2001 had 15 percent chance of being alive 5 years later. For patients with stage IV disease, describing cancer that has spread to distant sites beyond the original tumor, that statistic drops to 2 percent. Now a University of Colorado Cancer Center study published in the Journal of Thoracic Oncology tells a much more optimistic story.
Hanoi, Vietnam, December 31, 2018--One in three people living with HIV in Vietnam remain undiagnosed, according to recent estimates. New strategies and models of HIV testing are urgently needed to reach undiagnosed populations and help them enroll in antiretroviral therapy (ART), in Vietnam and throughout the world.
(December 31, 2018--Abu Dhabi) -- A new NYU Abu Dhabi study suggests for the first time that Actin, which is a cytoskeleton protein found in the cell, is critical to regulating the genome - the genetic material of an organism - during the formation of "neurons" or nerve cells. The study was published today in PLOS Genetics.
Bottom Line: Nearly 9,000 children and adolescents died from opioid poisonings with prescription and illicit drugs between 1999 and 2016 based on an analysis of national data. The death rate almost tripled over that time to nearly 1 per 100,000 based on the data from the Centers for Disease Control and Prevention (CDC). Prescription opioids were implicated in 73 percent of the deaths (6,561) and most of the deaths were unintentional (nearly 81 percent).