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WASHINGTON -- A new study suggests that Oncotype DX-guided treatment could reduce the cost for the first year of breast cancer care in the U.S. by about $50 million (about 2 percent of the overall costs in the first year). The study by Georgetown Lombardi Comprehensive Cancer Center and National Cancer Institute researchers was published April 24, in JNCI.
PHILADELPHIA (April 24, 2019) - Scientists from the Monell Center report that functional olfactory receptors, the sensors that detect odors in the nose, are also present in human taste cells found on the tongue. The findings suggest that interactions between the senses of smell and taste, the primary components of food flavor, may begin on the tongue and not in the brain, as previously thought.
Popular electronic cigarette (e-cigarette) products sold in the U.S. were contaminated with bacterial and fungal toxins, according to new research from Harvard T.H. Chan School of Public Health.
Leuven, Belgium - Societies and schools are facing new, culturally diverse populations and how they respond to these changes can have lasting impacts for everyone involved. Examining middle school diversity policies, a team of researchers from the University of Leuven, Belgium and the Queen's University Belfast, UK, found that in schools with multicultural-based policies, ethnic minority students achieved just as well and felt that they belonged just as much as their majority peers.
In a recent study in mice, researchers found a way to deliver specific drugs to parts of the body that are exceptionally difficult to access. Their Y-shaped block catiomer (YBC) binds with certain therapeutic materials forming a package 18 nanometers wide. The package is less than one-fifth the size of those produced in previous studies, so can pass through much smaller gaps. This allows YBCs to slip through tight barriers in cancers of the brain or pancreas.
The precious chemistry of a plant used for 2000 years in traditional Chinese medicine has been unlocked in a project that raises the prospect of rapid access to a wide array of therapeutic drugs.
Carried out by CEPAMS - a partnership between the Chinese Academy of Sciences and the John Innes Centre - the project has successfully delivered a high-quality reference genome of the mint-family member Scutellaria baicalensis Georgi.
(CINCINNATI) When a protein named "Merlin" fails to do its job, people can develop slow-growing, life-disrupting auditory nerve tumors that can disrupt their hearing and balance. This rare condition is called neurofibromatosis 2 (NF2).
MOSS LANDING, CA--MBARI researchers recently measured high concentrations of carbon dioxide in air blowing out to sea from cities and agricultural areas, including Silicon Valley. In a new paper in PLOS ONE, they calculate that this previously undocumented process could increase the amount of carbon dioxide dissolving into coastal ocean waters by about 20 percent.
A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the central nervous system--including the retina of the eye--serve as "gatekeepers," or biosensors and facilitators, of neuroinflammation in a preclinical model of autoimmune uveitis. Uveitis is one of the leading causes of blindness, accounting for approximately 10% of significant visual impairment worldwide.
Physarum polycephalum is a complex single-cell organism that has no nervous system. It can learn and transfer its knowledge to its fellow slime moulds via fusion. How it did so was a mystery. Researchers at the Centre de Recherches sur la Cognition Animale (CNRS/UT3 Paul Sabatier)* have recently demonstrated that slime moulds learn to tolerate a substance by absorbing it.
Archaeological excavation has, historically, operated in a very hierarchical structure, according to archaeologist Allison Mickel. The history of the enterprise is deeply entangled with Western colonial and imperial pursuits, she says. Excavations have been, and often still are, according to Mickel, led by foreigners from the West, while dependent on the labor of scores of people from the local community to perform the manual labor of the dig.
Fasciola hepatica is a parasite that causes on average 3.2 million in losses in the agricultural sector every year worldwide. It is a two-centimeter-long worm at adult size that mainly affects ruminants by means of water or raw vegetables that act as vehicles of infection. Moveover, in developing countries with deficient sanitary control systems, more than five million people have been infected. Though it does not have high death rates, it causes liver damage and makes the host more prone to catching other diseases.
Fire ecologists and wildlife specialists at La Trobe University have made key discoveries in how wildlife restores itself after bushfires, and what Australian conservationists can do to assist the process.
The study, published this week in Wildlife Research journal, looks at various reserves in the Australian state of Victoria after bushfires had taken place. It finds that the surrounding area of any fire dictates what species survived and went onto thrive.
Key findings of the study included:
Researchers from HSE University and London Business School have carried out research into the dynamics of the prices for Russian companies' stocks and depositary receipts. The research indicates that, thanks to their price differences, there are opportunities for profitable trading with zero or, at least, minimum risk.
https://www.tandfonline.com/doi/full/10.1080/1540496X.2018.1564276?scroll=top&needAccess=true
As genome sequencing becomes cheaper and faster, resulting in an exponential increase in data, the need for efficiency in predicting gene function is growing, as is the need to train the next generation of scientists in bioinformatics. Researchers in the lab of Lukas Mueller, a faculty member of the Boyce Thompson Institute (BTI), have developed a strategy to fulfill both of these needs, benefiting students and researchers in the process.