Culture

Scientists have discovered that soil microbes can make plants more resistant to an aggressive disease - opening new possibilities for sustainable food production.

Bacterial wilt disease caused by Ralstonia solanacearum infects several plants including tomatoes and potatoes. It causes huge economic losses around the world especially in China, Indonesia and Africa.

Idiopathic pulmonary fibrosis (IPF) is a type of lung disease that results in scarring of the lungs, also known as fibrosis. Over time, the fibrosis gets increasingly worse so that it becomes hard for those with the condition to simply take in a deep breath to get the oxygen they need. However, it is not clear what the cause of this condition is, and while there are two treatments that can help slow the rate at which IPF progresses, there is currently no treatment that can stop or reverse the scarring of the lung.

A group of researchers at Baylor College of Medicine, the Texas Heart Institute and the University of Texas Health Science Center at Houston reveals today in the journal Genes & Development new insights into the recently discovered healing capacity of the heart involving the Hippo cellular pathway. The group previously reported that inactivating the Hippo pathway in the adult murine heart promoted cardiac muscle regeneration after injury, opening the possibility of developing promising heart failure therapies.

What The Study Did: Data from the UK Biobank were used to examine whether genetic risk to psychotic experiences is shared with neuropsychiatric disorders.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

Authors: James T. R. Walters, M.R.C.Psych., Ph.D., and Stanley Zammit, M.R.C.Psych., Ph.D., of Cardiff University in Cardiff, United Kingdom, are the corresponding authors.

(doi:10.1001/jamapsychiatry.2019.2508)

A research team has created CAR T cells that target an alternative B cell-specific surface marker, allowing them to effectively kill blood cancer cells that lack the prototypical target for CAR T therapy, CD19. The new T cells could help clinicians avoid the relapses that can occur in patients whose lymphoma cells lose CD19 - a prominent roadblock in standard CAR T cell therapy for B cell malignancies. CAR T cells are a highly effective therapy for blood cancers that have become resistant to standard treatments.

People are less motivated to take actions if its outcome is uncertain, and this could be true for climate-related issues. The uncertainty in climate response to the increase in greenhouse gas concentration, which is often believed to be substantially large, makes it difficult to believe the benefit of reducing emissions or the effectiveness of making society more resilient to climate-related hazards. This could be one of the reasons for inaction even though urgent action is called for.

Originally from Africa, chikungunya is aptly named. It derives from a word in the Kimakonde language, meaning "to become contorted", because the severe muscle and joint pains endured by the patients prevent them from moving normally or performing their daily activities.

A new study of African Americans with poorly controlled asthma, found differences in patients' responses to commonly used treatments. Contrary to what researchers had expected, almost half of young children in the study responded differently than older children and adults, and than white children in prior studies.

Myelodysplastic syndrome (MDS), one of the most common blood cancers, has very few treatment options. Now, researchers at Cold Spring Harbor Laboratory (CSHL) have discovered a new and promising drug target for this deadly condition.

"At the moment, only a small portion of patients benefit from the standard therapy for MDS," said CSHL Fellow and cancer researcher Lingbo Zhang. "Therefore, there is a very important medical need for a new and novel therapy for this disease."

Kanazawa, Japan - Contrary to popular belief, there may be more than one mechanism involved in microbial airway protection. Researchers from Japan and China have found an alternative mechanism that may be involved in fighting microbial infections.

Millions of people across the globe are suffering from malnutrition despite some of the most nutritious fish species in the world being caught near their homes, according to new research published in Nature today.

Scientists from the ARC Centre of Excellence for Coral Reef Studies at James Cook University (Coral CoE at JCU) are part of an international team that found children in many tropical coastal areas could see significant health improvements if just a fraction of the fish caught nearby was diverted into their diets.

People today constantly encounter claims such as "Advil kills pain," "coffee prevents depression," or "Hilary promises amnesty" as brands, news outlets and social media sites vie for our attention--yet few people take the time to investigate whether these statements are true. Researchers have now uncovered one of the subtle psychological variables that influences whether people deem a claim to be true or false: the sequence of the letters.

Scientists at the Center for Advancing Electronics Dresden (cfaed) at TU Dresden have succeeded in synthesizing sheet-like 2D polymers by a bottom-up process for the first time. A novel synthetic reaction route was developed for this purpose. The 2D polymers consist of only a few single atomic layers and, due to their very special properties, are a promising material for use in electronic components and systems of a new generation.

Bacteria have no mouth. They eat by absorbing substances from their environment via their cell wall. However, there are natural physical limits to this way of "eating". To bypass these limits, some bacteria enlarge their cell surface. For example, they form tubular extensions or small bubbles, so called vesicles. A group of researchers led by Jens Harder from the Max Planck Institute for Marine Microbiology in Bremen, Germany, has now observed for the first time that bacteria initially form tubes and then vesicles.

North Sea bacteria with pearl chains

LAWRENCE -- Courses in introductory physics are required for nearly all university STEM degree programs not only because physics is considered foundational to those disciplines, but also because it provides students practical experience in applied mathematics. The latter is especially true for calculus-based physics courses, which typically provide students their first exposure to using calculus outside of their math classes.