Culture

Amsterdam, July 20, 2021 - Well over six million people globally have been diagnosed with Parkinson's disease (PD), which has an enormous impact on the lives of patients, their families, and caregivers and is incurring mounting costs for society. This special supplement to the Journal of Parkinson's Disease (JPD), guest-edited by noted experts Anat Mirelman, PhD, E. Ray Dorsey, MD, MBA, Patrik Brundin, MD, PhD, and Bastiaan R.

MINNEAPOLIS/ST. PAUL (07/20/2021) -- National data analyzed by University of Minnesota Medical School researchers show that nearly 40 percent of all funds used to pay for medical school are expected to come from family or personal sources and scholarships. The prevalence of these sources, however, varies widely by race and socioeconomic status.

Despite the best efforts of industry to work towards sustainability, most plastics (or polymers) are still made using non-renewable fossil fuels. However, researchers have now found an economical method for producing biobased acrylate resins. The study, published in the journal Angewandte Chemie, shows how all the synthesis steps, from initial building blocks right up to polymerization, can be carried out in a single reactor (one pot), minimizing environmental impact.

Surgical scars treated with a molecule called alphaCT1 showed a long-term improvement in appearance when compared to control scars, according to multicenter, controlled Phase II clinical trials - a finding that could help surgeons improve patient outcomes.

When it was discovered in the 1980s in Argentina, this hadrosaur was diagnosed with a fractured foot. However, a new analysis now shows that this ornithopod commonly known as the duck-billed dinosaur actually had a tumour some 70 million years ago, as well as two painful fractures in the vertebrae of its tail, despite which, it managed to survive for some time.

PHILADELPHIA--Alzheimer's disease and related diseases can still only be confirmed in deceased patients' brains via autopsy. Even so, the development of biomarkers can give patients and their families answers during life: Alzheimer's disease can be accurately detected via peptides and proteins in a patient's cerebrospinal fluids (CSF), which can be collected through a lumbar puncture and tested while the patient is alive.

In order to correctly separate vehicles into classes, for instance for mobility pricing, one must be able to clearly distinguish mid-sized cars from upper class cars or small cars from compact cars. But this is becoming increasingly difficult: On photos, an Audi A4 looks almost the same as an Audi A6, a Mini One looks similar to a Mini Countryman. To date, there is no independent procedure for doing this.

FORT LAUDERDALE/DAVIE, Fla. - It's good to have friends.

FRANKFURT, GERMANY. When SARS-CoV-2 infects a cell, it introduces its RNA into it and re-programmes it in such a way that the cell first produces viral proteins and then whole viral particles. In the search for active substances against SARS-CoV-2, researchers have so far mostly concentrated on the viral proteins and on blocking them, since this promises to prevent, or at least slow down, replication. But attacking the viral genome, a long RNA molecule, might also stop or slow down viral replication.

Neurons communicate through rapid electrical signals that regulate the release of neurotransmitters, the brain's chemical messengers. Once transmitted across a neuron, electrical signals cause the juncture with another neuron, known as a synapse, to release droplets filled with neurotransmitters that pass the information on to the next neuron. This type of neuron-to-neuron communication is known as evoked neurotransmission.

Forensics specialists can use a commercial assay targeting mitochondrial DNA to accurately discriminate between wolf, coyote and dog species, according to a new study from North Carolina State University. The genetic information can be obtained from smaller or more degraded samples, and could aid authorities in prosecuting hunting jurisdiction violations and preserving protected species.

In the U.S., certain wolf subspecies or species are endangered and restricted in terms of hunting status. It is also illegal to deliberately breed wolves or coyotes with domesticated dogs.

EAST LANSING, Mich. - Diagnosing a rare medical condition is difficult. Identifying a treatment for it can take years of trial and error. In a serendipitous intersection of research expertise, an ill patient in this case a child and innovative technology, Bachmann-Bupp Syndrome has gone from a list of symptoms to a successful treatment in just 16 months.

The paper chronicling this lightning-fast scientific response to the Bachmann-Bupp Syndrome was published in the open-access journal, eLife.

With more than two-thirds of American adults vaccinated with at least one dose of an authorized Covid-19 vaccine, the top U.S. health agencies retain the trust of the vast majority of the American public, as does Dr. Anthony Fauci, the public face of U.S. efforts to combat the virus, according to a new survey from the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.

The survey revealed growing public confidence in both the safety and effectiveness of vaccines to prevent Covid-19.

Led by Dr Jonas Warneke, researchers at the Wilhelm Ostwald Institute of Physical and Theoretical Chemistry at Leipzig University have made a decisive advance in the study of one type of highly reactive particles. Based on their research, they now understand the "binding preferences" of these particles.

We all like to think that we know ourselves best, but, given that our brain activity is largely governed by our subconscious mind, it is probably our brain that knows us better! While this is only a hypothesis, researchers from Japan have already proposed a content recommendation system that assumes this to be true. Essentially, such a system makes use of its user's brain signals (acquired using, say, an MRI scan) when exposed to a particular content and eventually, by exploring various users and contents, builds up a general model of brain activity.