Culture

Bacteria can still develop antibiotic resistance even in the face of challenging genetic tradeoffs, or compromises, associated with varying antibiotic concentrations, says a new study published today in eLife.

The rapid emergence of bacteria that are resistant to antibacterial drugs is a growing global health crisis. The findings provide valuable new insights on how different concentrations of drugs affect the evolution of resistance in Escherichia coli (E. coli) bacteria, which can cause life-threatening blood infections.

CORVALLIS, Ore. - Hop-based dietary supplements that many women use to ease the night sweats and hot flashes commonly reported during menopause aren't likely to cause drug interactions, new research from Oregon State University's Linus Pauling Institute and College of Pharmacy shows.

CORVALLIS, Ore. - Standup comedian Jon the Robot likes to tell his audiences that he does lots of auditions but has a hard time getting bookings.

"They always think I'm too robotic," he deadpans.

If raucous laughter follows, he comes back with, "Please tell the booking agents how funny that joke was."

If it doesn't, he follows up with, "Sorry about that. I think I got caught in a loop. Please tell the booking agents that you like me ... that you like me ... that you like me ... that you like me."

Washington, DC - May 19, 2020 -- Vaccines that protect people from infection by Streptococcus pneumoniae, which kills up to 1 million children ever year worldwide, train the immune system to recognize the pathogen's thick sugar capsule. Pneumococcus capsules are not only the active ingredient in vaccines; they're also key to the pathogen's virulence. But different strains have different capsules, which means vaccine researchers need to identify all capsule types.

As scientists across the globe race to develop a vaccine against SARS-CoV-2, the coronavirus that causes COVID-19, an international team led by Davide Corti at Vir Biotechnology and David Veesler at the University of Washington has been working around the clock on a complementary approach - identifying neutralizing antibodies that could be used as a preventative treatment or as a post-exposure therapy.

Korea Brain Research Institute (KBRI, President Pann Ghill Suh) announced on May 19 that its research team led by Dr. Jae-Yeol Joo and Dr. Key-Hwan Lim discovered, for the first time in the world, an increased specific expression of the Ube2h gene in the blood of AD patients.

The findings were published in the May Special Issue of the International Journal of Molecular Sciences (IJMS). The title and authors of the paper are as follows:

Most people with severe coronavirus infections (ie, SARS, MERS, and COVID-19) appear to recover without experiencing mental illness.

Delirium may feature in the acute stages of COVID-19, and clinicians should be aware of potential long-term mental health effects such as depression, anxiety, fatigue, and PTSD in the wake of the COVID-19 pandemic.

With only 12 low-to-moderate quality COVID-19 studies (including seven non-peer reviewed preprints) to draw on, and no post-recovery data, continued research will be needed.

People taken ill by coronavirus infections may experience psychiatric problems while hospitalised and potentially after they recover, suggests an analysis of past research led by the UCL Institute of Mental Health with King's College London collaborators.

The systematic review paper, published in The Lancet Psychiatry, compiled results from short- and long-term studies of people hospitalised by recent coronaviruses, namely SARS (Severe acute respiratory syndrome) in 2002-2004, MERS (Middle East respiratory syndrome) in 2012, as well as COVID-19 this year.

People living in low-income, disadvantaged communities across much of urban Los Angeles lack the means to cool their homes, posing a growing threat to their health -- and their lives -- from extreme heat waves due to global warming, new USC research shows.

The communities across southern L.A. are most vulnerable, underscoring social inequities as a warming world affects populations differently. The USC research aims to help prepare the megalopolis for big disruptions, manifest in the coronavirus crisis today and climate change tomorrow.

DURHAM, N.C. -- In a recent study, Duke researchers tested whether a single infusion of a unit of a child's own or donor cord blood could improve social communication skills in children between the ages of 2-7 diagnosed with autism spectrum disorder.

Of the 180 children in the study, the subgroup of children without an intellectual disability showed improvements in language communication, ability to sustain attention measured via eye tracking, and increased alpha and beta EEG power, a measure of brain function.

Talk about motherly instincts: Biologists at the University of Iowa have learned that female roundworms can alert their future offspring of dangers they will encounter when born, and the mothers pass on these warnings even before the offspring have been conceived.

Computing - Mining for COVID-19 connections

Scientists have tapped the immense power of the Summit supercomputer at Oak Ridge National Laboratory to comb through millions of medical journal articles to identify potential vaccines, drugs and effective measures that could suppress or stop the spread of COVID-19.

An accumulation of an unexpected intermediate of the peptidoglycan recycling pathway that is able to modulate the synthesis and structure of the cell wall, has been found by researchers at Umeå University, Sweden.

Despite physical distance, it's possible to create proximity between family members located in different places. This is according to a study from Linköping University that has investigated how video calls bring family members together. The results show that proximity in video calls is established mainly by way of the body and the senses, e.g. by giving a digital high five.

When COVID-19 patients are critically ill, the biggest threat to their lives is lung dysfunction. If their lungs don't work, their blood can't circulate enough oxygen to the brain, the liver and other organs.