Culture
Osaka, Japan - Cells are like tiny self-contained machines that are constantly fine-tuned in response to both internal and external signals. Some of these signals are induced by extracellular ligands, specialized proteins that bind to specific receptors on the cell surface, stimulating signaling pathways and altering gene expression.
Antibodies for potential use as medicines can be made rapidly in chicken cells grown in laboratories. Researchers refer to their technique as the human ADLib system, short for autonomously diversifying libraries. The technique automatically builds vast numbers, or libraries, of diverse antibodies using chicken immune system cells' natural method for shuffling their genes.
There is an extremely high probability that individuals with 22q11.2 micro deletion syndrome - a rare genetic disorder - will develop schizophrenia together with one of its most common symptoms, auditory hallucinations. Scientists at the University of Geneva (UNIGE) and the Synapsy National Centre of Competence in Research (NCCR) have been studying this category of patients. They have succeeded in linking the onset of this hallucinatory phenomenon with the abnormal development of certain substructures of a region deep in the brain called the thalamus.
GP's notes currently unavailable to medical researchers could provide clues to help manage major health crises - like COVID-19.
And according to a 'citizens' jury' study at Brighton and Sussex Medical School (BSMS), the main thing stopping the use of such information - concerns over patient privacy - could be overcome.
Few species develop as slowly as humans, both in terms of developing adult skills and in terms of brain development. Human infants are born so underdeveloped that they cannot survive without adult care and feeding for some years after birth. Children still need to learn fundamental skills such as walking, eating, talking, using tools and much more. The timing of when these developmental milestones emerge is used by doctors to determine if your child and your child's brain are developing normally.
At any given moment, a variety of dynamic processes occur inside a cell, with many developing over time. Because current research methods for gene profiling or protein analysis destroy the cell, study is confined to just that one moment in time, and researchers are unable to return to the cell to examine how things change beyond that snapshot.
DALLAS, May 26, 2020 -- Higher spirituality among stroke survivors was strongly linked to better quality of life for them and their caregivers who may also feel depressed, according to new research published today in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal. May is American Stroke Month.
For many stroke survivors, a caregiver, often a family member or close friend, may help with daily tasks, making the survivor and the caregiver prone to depression. Depression can impact quality of life for both.
Having a faulty gene linked to dementia doubles the risk of developing severe COVID-19, according to a large-scale study.
Shea yields are likely to benefit from a diversity of trees and shrubs in parkland habitats in West Africa, according to a new study led by scientists from Trinity College Dublin. The findings have important implications for managing a crop that is typically harvested and sold by women in rural areas, and which helps finance education for children.
A child's unique brain activity reveals how good their memories are, according to research recently published in JNeurosci.
When you scramble to remember a phone number as you enter it into your phone, you rely on your working memory to keep the number at the front of your mind. Briefly holding and manipulating information relies on the activity of the frontoparietal network, a group of brain regions coined the "cognition core." Working memory performance changes throughout development, but can an individual's memory facility be determined based on brain activity?
A team led by scientists from the Institut Jacques Monod (CNRS/Université de Paris)* have shown that French prehistory was punctuated by two waves of migration: the first during the Neolithic period, about 6,300 years ago, the second during the Bronze Age, about 4,200 years ago.
When University of Ottawa biologists Kim Mitchell and Vance Trudeau began studying the effects of gene mutations in zebrafish, they uncovered new functions that regulate how males and females interact while mating. We sat down with senior author Professor Trudeau, Research Chair in Neuroendocrinology at the Faculty of Science, to learn more.
Please tell us about this research project.
Patients with heart failure who experience low health literacy are at an increased risk of hospitalization and mortality. This finding has significant clinical and public health implications and suggests that assessing and intervening upon an individual's understanding of their own health could improve heart failure outcomes, according to research published in JACC: Heart Failure.
Researchers have found a way to design an antibody that can identify the toxic particles that destroy healthy brain cells - a potential advance in the fight against Alzheimer's disease.
Their method is able to recognise these toxic particles, known as amyloid-beta oligomers, which are the hallmark of the disease, leading to hope that new diagnostic methods can be developed for Alzheimer's disease and other forms of dementia.
Space is getting crowded. Aging satellites and space debris crowd low-Earth orbit, and launching new satellites adds to the collision risk. The most effective way to solve the space junk problem, according to a new study, is not to capture debris or deorbit old satellites: it's an international agreement to charge operators "orbital-use fees" for every satellite put into orbit.