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CLEVELAND - An international team of researchers co-led by Cleveland Clinic have identified why patients without PTEN mutations may still experience the high cancer risk associated with PTEN hamartoma tumor syndrome (PHTS).
In a new study published in the New England Journal of Medicine, a research team co-led by Charis Eng, MD, PhD, Cleveland Clinic Genomic Medicine Institute, and Pier Paolo Pandolfi, MD, PhD, FRCP, University of Turin, Italy, found that mutations to the gene WWP1 may be an additional genetic driver of PHTS-associated cancer.
Researchers from Newcastle University London, Fordham University, and University of Minho published a new paper in the Journal of Marketing that examines how some brands create "sticky" customer journeys that keep customers addicted.
The study forthcoming in the Journal of Marketing is titled "Customer Experience Journeys: Loyalty Loops versus Involvement Spirals" and is authored by Anton Siebert, Ahir Gopaldas, Andrew Lindridge, and Cláudia Simões.
Although we often think of knowledge as "knowing that" (for example, knowing that Paris is the capital of France), each of us also knows many procedures consisting of knowing how, such as knowing how to tie a knot or start a car. Now a new study has found the brain programs that code the sequence of steps in performing a complex procedure.
Below please find a summary and link(s) of new coronavirus-related content published today in Annals of Internal Medicine. The summary below is not intended to substitute for the full article as a source of information. A collection of coronavirus-related content is free to the public at http://go.annals.org/coronavirus.
1. Risk for COVID-19 Resurgence Related to Duration and Effectiveness of Physical Distancing in Ontario, Canada
Chemical engineering researchers at the University of Arkansas have developed a device that simulates the blood filtering and ion transport functions of the human kidney. The technology could transform treatment options for people in the final stage of renal disease.
As small businesses reopen after a lengthy pandemic shutdown, one key challenge will be finding working capital to replenish inventories and pay employees until revenue returns to normal, according to a new RAND Corporation perspective based on interviews with a select group of small business owners.
Business owners believe it will take many months to return to normal, and that process can be aided by clear guidance from government or trade organizations about how to reopen safely during the pandemic. This includes how to keep both workers and customers safe.
ANN ARBOR, Mich. - After experiencing an ACL injury, a common sports injury involving ligaments in the knee, many athletes find they can't return to play with the same vigor as before their injury. But, a new study, published in The American Journal of Sports Medicine, finds human growth hormone treatment after ACL reconstructive surgery may prevent the loss of muscle strength in the knee.
Nearly half of individuals who contract COVID-19 experience changes in their sense of taste, a new analysis led by a University of Toledo researcher has found.
The systematic review, published in the journal Gastroenterology, could provide yet another diagnostic hint for clinicians who suspect their patients might have the disease.
Offering a government-sponsored health plan with publicly determined payment rates to people who buy their own insurance could lower the cost of premiums, but on its own it is unlikely to substantially increase the overall number of people with coverage, according to a new RAND Corporation study.
Modeling four scenarios for adding a public option for individual coverage available nationwide, researchers found that premiums for public plans could be 10% to 27% lower than private insurance plans because of lower provider payment rates in the public option.
WASHINGTON -- The amount of scarring in damaged kidneys as a result of diabetes or acute injury, is a key factor in determining treatment. But it has not been possible, using traditional techniques, to quickly and accurately assess how widespread this kind of wounding extends within the organ. Now, however, a physicist and chemist at Georgetown University Medical Center has shown that a microscope he began developing with colleagues at University of California-Irvine can provide an immediate answer.
Perennial warm-season grasses do not provide high-quality forage during mid to late-summer, which limits yearling stocker cattle from maintaining high rates of growth in the Southern Great Plains. This shortage has resulted in a continual search by researchers for annual legumes that can provide sufficient amounts of nutritious forage during August through September.
Among dinosaurs of ancient Colorado, scavenging and possibly cannibalism were responses to a resource-scarce environment, according to a study published May 27, 2020 in the open-access journal PLOS ONE by Stephanie Drumheller of the University of Tennessee, Knoxville, and colleagues.
Meta-analysis research studies in psychology aren't always reproducible due to a lack of transparency of reporting in the meta-analysis process, according to a new study published May 27, 2020 in the open-access journal PLOS ONE by Esther Maassen of Tilburg University, the Netherlands, and colleagues.
For many patients with a bicuspid aortic valve that needs replacing, transcatheter aortic valve replacement (TAVR) appears to be a safe treatment option with low complication rates, according to a study published in JACC: Cardiovascular Interventions. The study found patients with bicuspid valves who were at increased risk for surgery had a 30-day and one-year mortality rate and stroke rate that was similar to patients with the more common tricuspid valves.
What The Study Did: Researchers looked at trends in diversity by sex and race/ethnicity among applicants to U.S. surgical residency and fellowship programs from 2008-2018 to see if diversity was increasing.
Authors: Issam Koleilat, M.D., of the Montefiore Medical Center in New York, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamasurg.2020.1018)