Culture

What The Study Did: Researchers estimated the frequency and magnitude of surprise bills for deliveries and newborn hospitalizations, which are the leading reasons for hospitalization in the United States, to illustrate the  potential benefits of federal legislation that will protect families from most surprise bills. Potential surprise bills were defined as claims from out-of-network clinicians and ancillary service providers, such as an ambulance.

Authors: Kao-Ping Chua, M.D., Ph.D., of the University of Michigan Medical School in Ann Arbor, is the corresponding author.

The human brain is a wonderfully enigmatic organ, helping to juggle multiple tasks efficiently to help us get through a long day! This feature, called executive function, seats primates like us at the pinnacle of evolution. The prospect of losing the spectacular flow of neural information in our brains because of an accident or disease is, thus, unnerving.

Guadalupe fur seals (Arctocephalus townsendi) have established a large resting colony in the Gulf of California--bringing the total number of sites where this endangered species now occurs to just four. This new haul-out was discovered on El Farallón de San Ignacio Island, along the mainland coast of Mexico, according to researchers from Mexico and the University of British Columbia.

Fukuoka, Japan--Medical researchers led by Kyushu University have revealed a possible underlying genetic pathway behind the neurological dysfunction of Rett syndrome. The team found that deficiencies in key genes involved in the pathology triggers neural stem cells to generate less neurons by producing more astrocytes--the brain's maintenance cells.

The researchers hope that the molecular pathology they identified, as reported in the journal Cell Reports, can lead to potential therapeutic targets for Rett syndrome in the future.

Japanese astronomers have developed a new artificial intelligence (AI) technique to remove noise in astronomical data due to random variations in galaxy shapes. After extensive training and testing on large mock data created by supercomputer simulations, they then applied this new tool to actual data from Japan's Subaru Telescope and found that the mass distribution derived from using this method is consistent with the currently accepted models of the Universe. This is a powerful new tool for analyzing big data from current and planned astronomy surveys.

Microorganisms produce natural products, for example, as disease-causing virulence factors or as defense substances against predators and competitors. A team led by Dr. Robin Teufel and first author Ying Duan from the Institute of Biology II at the Faculty of Biology of the University of Freiburg, together with researchers from the University of Bonn, have now discovered a novel enzyme that is crucial for the production of so-called bacterial tropone natural products. The researchers presented their results in the current issue of the Journal of the American Chemical Society.

"We have studied which temperatures are preferable and which are harmful in humans, cattle, pigs, poultry, and agricultural crops and found that they are surprisingly similar," says Senthold Asseng, Professor of Digital Agriculture at TUM. According to the study, preferable temperatures range from 17 to 24 degrees Celsius.

When does it become too hot for humans?

Plastics are a growing problem for natural ecosystems around the globe, and in particular for our marine and freshwater environments. Rivers are the leading source of plastic pollution, as it has been estimated that they deliver several million metric tons of plastic annually to our oceans from poor land-based waste management. The problem is that the estimates made for plastics flowing from the rivers are tens to hundreds of times higher than the quantity of plastics floating on the ocean's surface.

Originally discovered as a bacterial mode of defense against invading viruses, the remarkable ability of CRISPR-Cas9 to modify specific locations of DNA has made it a researcher favorite among gene editing tools. The ongoing effort to explore further possibilities of the CRISPR-Cas9 system is ushering in newer developments to this tool. In one of the latest refinements of the technique, as illustrated in a study published in BioDesign Research, scientists from Stanford University, USA have developed a CRISPR-Cas9 system that induces highly effective silencing of target genes.

Elephants and their forebears were pushed into wipeout by waves of extreme global environmental change, rather than overhunting by early humans, according to new research.

Understanding how viral infection occurs can provide important clues for researchers to develop strategies to prevent viral transmission and develop effective therapeutic agents and vaccines. SARS-CoV-2, the causative agent of COVID-19, enters the host cells through interaction between the virus's spike protein and the extracellular receptor binding domain of ACE2. The viral entry into the cells is completed by various proteases, which allow the viral and cell membranes to fuse together.

A water disinfectant created on the spot using just hydrogen and the air around us is millions of times more effective at killing viruses and bacteria than traditional commercial methods, according to scientists from Cardiff University.

Reporting their findings today in the journal Nature Catalysis, the team say the results could revolutionise water disinfection technologies and present an unprecedented opportunity to provide clean water to communities that need it most.

As many expectant mothers know, getting enough folate is key to avoiding neural tube defects in the baby during pregnancy. But for the individuals who carry certain genetic variants, dealing with folate deficiency can be a life-long struggle which can lead to serious neurological and heart problems and even death.

Now a Donnelly Centre study offers clues to how to recognize early those who are most at risk.

While autistic individuals are less likely to use substances, those who do so are more likely to self-medicate for their mental health symptoms, according to new research from the University of Cambridge and published today in The Lancet Psychiatry.