Low levels of both oxygen and the powerful blood vessel dilator nitric oxide appear to have an unfortunate synergy for patients with sickle cell disease, researchers report.
Their studies indicate that the two conditions common in sickle cell disease, dramatically increase red blood cells' adhesion to the lining of blood vessels walls and the debilitating pain crises that can result.
Seabirds, sea turtles and marine mammals such as dolphins may not appear to have much in common, other than an affinity for open water. The sad truth is that they are all unintended victims – by-catch – of intensive global fishing. In fact, accidental entanglement in fishing gear is the single biggest threat to some species in these groups.
A new analysis co-authored by Stanford biology Professor Larry Crowder provides an unprecedented global map of this by-catch, starkly illustrating the scope of the problem and the need to expand existing conservation efforts in certain areas.
Washington, DC (March 20, 2014) — Medical research funding from public and private sources is at an all-time low. A new Journal of the American Society of Nephrology (JASN) article discusses the effects of such funding constraints, with a focus on the plight of kidney research.
PHILADELPHIA – The decision to initiate dialysis for acute kidney injury (AKI) varies depending on different patient factors and there is a lack of robust evidence as to which patients are likely to benefit most and why. A new study from researchers at the Perelman School of Medicine at the University of Pennsylvania has shown that for patients with lower creatinine concentration levels – a sign of reduced muscle mass and weakness – initiation of dialysis could actually be detrimental.
In a world perfumed by freshly popped popcorn and exhaust fumes, where sea breezes can mingle with the scents of sweet flowers or wet paint, new research has found that humans are capable of discriminating at least one trillion different odors. Howard Hughes Medical Institute (HHMI) scientists determined that our sense of smell is prepared to recognize this vast olfactory palette after testing individuals' ability to recognize differences between complex odors mixed in the laboratory.
Neuroscientists Vanessa Moraïs and Bart De Strooper from VIB and KU Leuven have demonstrated how a defect in the gene Pink1 results in Parkinson's disease. By mapping this process at a molecular level, they have provided the ultimate proof that a deficient energy production process in cells can result in Parkinson's disease. These insights are so revolutionary that they have been published in the leading journal Science.
Vanessa Moraïs (VIB/KU Leuven):
ROCHESTER, Minn. — March 20, 2014 — Is irritable bowel syndrome (IBS) caused by genetics, diet, past trauma, anxiety? All are thought to play a role, but now, for the first time, researchers have reported a defined genetic defect that causes a subset of IBS. The research was published in the journal Gastroenterology.
WASHINGTON — The implementation of health care reform in Massachusetts – principally the expansion of health insurance coverage to nearly everyone in the state – was associated with a small but consistent increase in emergency department use, according to the findings of a study to be published online today in Annals of Emergency Medicine ("Increased Use of the Emergency Department After Health Care Reform in Massachusetts").
Lincoln, Neb., March 20, 2014 – The nation's left-leaning citizens might be pleased by the findings of a new University of Nebraska study that finds those who live in liberal states tend to be healthier.
But conservatives could also take satisfaction in the same study's conclusion that strong communities also foster better health.
CHAMPAIGN, Ill. — New research from two University of Illinois economics professors who study election trends analyzes how polarization on social issues affects competing candidates' economic platforms.
In the paper, co-authors Stefan Krasa and Mattias Polborn develop a theory of candidate competition that accounts for the influence of both economic and cultural issues on individual voting behavior.
Interim analysis of the intergroup EORTC-LYSA-FIL 20051 H10 trial published in the Journal of Clinical Oncology indicates an increased risk of early relapse when omitting radiotherapy in early PET scan negative patients with stage I/II Hodgkin's lymphoma. Early outcome, however, was excellent in both arms, and the final analysis should reveal whether these initial findings are maintained over time.
BOSTON – Emergency department usage in Massachusetts rose slightly both during and immediately after implementation of a 2006 state law expanding health care access, a sign that broader availability of insurance may increase use of the ED, Beth Israel Deaconess Medical Center researchers report in a study published in the Annals of Emergency Medicine.
HUNTSVILLE, TX (3/20/14) -- Parents who use alcohol, marijuana, and drugs have higher frequencies of children who pick up their habits, according to a study from Sam Houston State University.
Low levels of both oxygen and the powerful blood vessel dilator nitric oxide appear to have an unfortunate synergy for patients with sickle cell disease, researchers report.
Their studies indicate that the two conditions common in sickle cell disease, dramatically increase red blood cells' adhesion to the lining of blood vessels walls and the debilitating pain crises that can result.