Culture

Effect of topical antibiotics on antibiotic resistance, patient outcomes in ICUs

A comparison of prophylactic antibiotic regimens applied to an area in the mouth and throat and digestive tract were associated with low levels of antibiotic-resistant bacteria and no differences in patient survival and intensive care unit (ICU) length of stay, according to a study published in JAMA. The study is being posted early online to coincide with its presentation at the European Society of Intensive Care Medicine annual congress.

Results of large-scale roll out of combination treatment for kala-azar in Eastern Africa

Today in Bahir Dar, Ethiopia, at the occasion of the Leishmaniasis East Africa Platform meeting, which has gathered some 150 African and international leishmaniasis experts, results of a pharmacovigilance – or large-scale treatment safety and efficacy monitoring – plan, carried out by MSF, DNDi, and national partners in Kenya, Sudan, Uganda, and Ethiopia, were presented to key decision makers in order to boost patient access to treatment of kala-azar with the combination of Sodium Stibogluconate and Paromomycin (SSG&PM) in the region.

Long-acting insulin is safer, more effective for patients with Type 1 diabetes

TORONTO, Oct. 1, 2014 – Long-acting insulin is safer and more effective than intermediate-acting insulin for patients with Type 1 diabetes, according to new research published in the BMJ.

Researchers looked at once-daily and twice-daily doses of both long- and intermediate-acting insulin, ranking their effectiveness, safety and cost-effectiveness.

Non-citizens face harsher sentencing than citizens in US criminal courts

WASHINGTON, DC, September 29, 2014 — Non-Americans in the U.S. federal court system are more likely to be sentenced to prison and for longer terms compared to U.S. citizens, according to a new study.

Healthy lifestyle could prevent nearly half of all diabetic pregnancies

Gestational diabetes is a common pregnancy complication that has long-term adverse health implications for both mothers and babies.

Several modifiable risk factors before pregnancy have been identified over the past decade. These include maintaining a healthy weight, consuming a healthy diet, regular physical activity, and not smoking.

Preterm birth complications and pneumonia are the leading causes of infants - study

Complications from preterm (premature) births and pneumonia are now the leading causes of death in children under five years, together responsible for nearly 2 million deaths in 2013, according to the latest estimates, published today [Tuesday 30 September] in The Lancet.

Researchers led by Professor Robert Black, of Johns Hopkins Bloomberg School of Public Health, Baltimore, USA, used the latest available data and modelling methods to examine what caused an estimated 6•3 million deaths of newborn babies (neonates) and children under five years in 2013.

Rehospitalization in younger patients

Older adults often are readmitted after hospitalization for heart failure, pneumonia, and acute myocardial infarction, a significant issue that has caused Medicare to target hospitals with high 30-day readmission rates for financial penalties. Older adults are also often admitted for reasons other than the original hospitalization. This vulnerability to readmission has been referred to as "post-hospital syndrome." However, whether younger patients also experience a similar pattern of readmission has not been well studied.

Diuretics in proton pump inhibitor-associated hypomagnesemia

Proton pump inhibitor (PPI) therapy is associated with hospitalization for hypomagnesemia, particularly among patients also receiving diuretics, according to research published this week in PLOS Medicine. The study, conducted by David Juurlink of the University of Toronto and colleagues, suggests that physicians reconsider long-term PPI therapy for patients with a diagnosis of hypomagnesemia or concurrent use of diuretics.

Low social support linked to poor health in young heart attack survivors

Having few friends, family and a general lack of social support is associated with poor health and quality of life and depression in young men and women a year after having a heart attack, according to new research in the Journal of the American Heart Association.

Study finds acupuncture does not improve chronic knee pain

Among patients older than 50 years with moderate to severe chronic knee pain, neither laser nor needle acupuncture provided greater benefit on pain or function compared to sham laser acupuncture, according to a study in the October 1 issue of JAMA.

Use of a 'virtual ward' model of care does not reduce hospital readmissions, risk of death

In a trial involving patients at high risk of hospital readmission or death, use of a virtual ward model of care (using some elements of hospital care in the community) after hospital discharge did not significantly reduce the rate of readmission or death up to a year following discharge, according to a study in the October 1 issue of JAMA.

Study compares long-term outcomes for types of aortic valve replacements

Among patients ages 50 to 69 years who underwent aortic valve replacement with bioprosthetic (made primarily with tissue) compared with mechanical prosthetic valves, there was no significant difference in 15-year survival or stroke, although patients in the bioprosthetic valve group had a greater likelihood of reoperation but a lower likelihood of major bleeding, according to a study in the October 1 issue of JAMA.

Clinical trial finds virtual ward does not reduce hospital readmissions

TORONTO — A virtual ward, a new model of care that provides support to high-risk and complex patients in the community for a few weeks after discharge from hospital, did not prevent hospital readmissions as hoped in a clinical trial in Toronto.

Hospital readmissions are common and costly and no intervention has reliably reduced them. Virtual wards, pioneered in Britain 10 years ago, were thought to have the potential to reduce readmissions, but had not been rigorously evaluated by researchers.

Medicaid and Uninsured patients obtain new patient appointments most easily at FQHCs

PHILADELPHIA – Federally Qualified Health Centers (FQHCs) granted new patient appointments to Medicaid beneficiaries and uninsured patients at higher rates than other primary care practices (non-FQHCs), in addition to charging less for visits, according to results of a new 10-state University of Pennsylvania study published this month in Medical Care.

Antioxidant found in grapes uncorks new targets for acne treatment

Got grapes? UCLA researchers have demonstrated how resveratrol, an antioxidant derived from grapes and found in wine, works to inhibit growth of the bacteria that causes acne.

The team also found that combining resveratrol with a common acne medication, benzoyl peroxide, may enhance the drug's ability to kill the bacteria and could translate into new treatments.