Culture

Results of new drug, ASP8273, show response in patients with treatment-resistant NSCLC

Barcelona, Spain: In a second presentation looking at new ways of treating non-small cell lung cancer (NSCLC) that has both the EGFR and T790M mutations, researchers will tell the 26th EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Barcelona, Spain, that an oral drug called ASP8273 has caused tumour shrinkage in patients in a phase I clinical trial in Japan.

Exercise may improve physical function, lessen pain in patients with kidney disease

Highlights

  • A 12-week course of aerobic exercise improved physical function and quality of life in patients with advanced chronic kidney disease.
  • The exercise program also decreased patients' pain.

More than 20 million people in the United States have chronic kidney disease.

Cost of meeting basic needs rising faster than wages in Washington state

A Washington family of four must spend 46 percent more on average to make ends meet today than 13 years ago, according to a new report from the University of Washington.

The Self-Sufficiency Standard for Washington State 2014, released Thursday (Nov. 20), provides a sobering look at how much it costs individuals and families statewide to meet basic needs -- and how far short they're falling.

Pain, magnet displacement in MRI in patients with cochlear implants

Pain, discomfort and magnet displacement were documented in a small medical records review study of patients with cochlear implants (CIs) who underwent magnetic resonance imaging (MRI), according to a report published online by JAMA Otolaryngology-Head & Neck Surgery.

Unstable child care can affect children by age 4

A new study from UNC's Frank Porter Graham Child Development Institute (FPG) reveals that disruptions in child care negatively affect children's social development as early as age 4. However, the study also shows that the effects of child care instability are not unduly large--and some types of instability appear to have no negative impact on children.

Contact lens discomfort linked to changes in lipid layer of tear film

November 20, 2014 - Changes in the lipid layer of the eyes' natural tear film may contribute to the common problem of contact lens discomfort, reports a study in the December issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

Gene therapy provides safe, long-term relief for patients with severe hemophilia B

(MEMPHIS, Tenn. - November 19, 2014) Gene therapy developed at St. Jude Children's Research Hospital, University College London (UCL) and the Royal Free Hospital has transformed life for men with a severe form of hemophilia B by providing a safe, reliable source of the blood clotting protein Factor IX that has allowed some to adopt a more active lifestyle, researchers reported. The results appear in the November 20 edition of The New England Journal of Medicine.

Heterosexuals have egalitarian views on legal benefits for same-sex couples, not on PDA

WASHINGTON, DC, November 18, 2014 -- A new study indicates that heterosexuals have predominately egalitarian views on legal benefits for -- but not public displays of affection (PDA) by -- same-sex couples.

Only half of patients take their medications as prescribed

The cost of patients not taking their medications as prescribed can be substantial in terms of their health. Although a large amount of research evidence has tried to address this problem, there are no well-established approaches to help them, according to a new systematic review published in the Cochrane Library. The authors of the review examined data from 182 trials testing different approaches to increasing medication adherence and patient health.

Terrorist attacks decrease fertility levels, says new research

A new study published online today in the journal Oxford Economic Papers has found that, on average, terrorist attacks decrease fertility, reducing both the expected number of children a woman has over her lifetime and the number of live births occurring during each year.

The Affordable Care Act in Kentucky, one year later

LOUISVILLE, Ky. - One year ago, Michael Stillman, M.D., and his colleague, Monalisa Tailor, M.D., both physicians with the University of Louisville Department of Medicine, wrote a New England Journal of Medicine "Perspective" article about "Tommy Davis," their pseudonym-named patient who delayed seeing a doctor because he lacked health insurance.

After spending a year experiencing severe abdominal pain and other symptoms, Davis finally sought care in the emergency room. The diagnosis? Metastatic colon cancer.

Delivering stem cells into heart muscle may enhance cardiac repair and reverse injury

Delivering stem cell factor directly into damaged heart muscle after a heart attack may help repair and regenerate injured tissue, according to a study led by researchers from Icahn School of Medicine at Mount Sinai presented November 18 at the American Heart Association Scientific Sessions 2014 in Chicago, IL.

New leadless pacemaker safe, reliable

A new self-contained leadless cardiac pacemaker is a safe and reliable alternative to conventional pacemakers, according to research presented at the American Heart Association's Scientific Sessions 2014.

The new device reduces complications that have existed over the last 50 years that are associated with lead placement and performance and the pulse generator situated under the skin that have occurred with conventional pacemaker systems.

More children surviving dilated cardiomyopathy without heart transplant

More children with dilated cardiomyopathy are surviving without a heart transplant, according to research presented at the American Heart Association's Scientific Sessions 2014.

Dilated cardiomyopathy occurs when the heart is enlarged (dilated) and the pumping chambers contract poorly (usually left side is worse than right). It can have genetic and infectious/environmental causes.

From architect to social worker: Complex jobs may protect memory and thinking later on

MINNEAPOLIS - People whose jobs require more complex work with other people, such as social workers and lawyers, or with data, like architects or graphic designers, may end up having longer-lasting memory and thinking abilities compared to people who do less complex work, according to research published in the November 19, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.