In an editorial published this week, the PLoS Medicine editors discuss how to maintain the integrity of the medical literature when publishing comparative effectiveness research (CER).
The U.S. government has allocated US$ 1.1 billion to fund CER, which will compare the benefits and harms of different approaches to medical care. As defined in a recent Institute of Medicine report, "the purpose of CER is to assist consumers, clinicians, purchasers, and policy makers to make informed decisions that will improve health care at both the individual and population levels."