Below please find a summary and link(s) of new coronavirus-related content published today in Annals of Internal Medicine. The summary below is not intended to substitute for the full article as a source of information. A collection of coronavirus-related content is free to the public at http://go.annals.org/coronavirus.
Quantifying and Interpreting Treatment Effects in COVID-19 Studies
Trials evaluating treatments for COVID-19 often use the time to a positive outcome as a key end point. In the presence of death as a competing risk, commonly used survival analysis techniques may not be appropriate. Using examples from two recent trials of treatments for COVID-19, the authors from Harvard University discuss issues with the current practice and present alternative, more clinically interpretable approaches. Read the full text: https://www.acpjournals.org/doi/10.7326/M20-4044.
Media contacts: PDFs for these articles is not yet available. Please click the link to read the full text. The lead author, Jason Lyell Vassy, MD, MPH, can be contacted directly at jvassy@partners.org.