Brain

UC Davis researchers have found novel compounds that disrupt the formation of amyloid, the clumps of protein in the brains of people with Alzheimer's disease believed to be important in causing the disease's characteristic mental decline. The so-called "spin-labeled fluorene compounds" are an important new target for researchers and physicians focused on diagnosing, treating and studying the disease.

The study, published today in the online journal PLoS ONE, is entitled "The influence of spin-labeled fluorene compounds on the assembly and toxicity of the Aβ peptide."

Migraine pain sits at the upper end of the typical pain scale – an angry-red section often labeled "severe." At this intensity, pain is debilitating. Yet many sufferers do not get relief from – or cannot tolerate – over-the-counter and commonly prescribed pain medications.

COLUMBIA, Mo. -- Contemplating death doesn't necessarily lead to morose despondency, fear, aggression or other negative behaviors, as previous research has suggested. Following a review of dozens of studies, University of Missouri researchers found that thoughts of mortality can lead to decreased militaristic attitudes, better health decisions, increased altruism and helpfulness, and reduced divorce rates.

A Northwestern University study that will be published in the Proceedings of the National Academy of Sciences (PNAS) provides the first biological evidence that bilinguals' rich experience with language in essence "fine-tunes" their auditory nervous system and helps them juggle linguistic input in ways that enhance attention and working memory.

Even low to moderate levels of exposure to the insecticide chlorpyrifos during pregnancy may lead to long-term, potentially irreversible changes in the brain structure of the child, according to a new brain imaging study by researchers from the Columbia Center for Children's Environmental Health at the Mailman School of Public Health, Duke University Medical Center, Emory University, and the New York State Psychiatric Institute. The changes in brain structure are consistent with cognitive deficits found in children exposed to this chemical.

ANN ARBOR, Mich. — Like a police officer calling for backup while also keeping a strong hold on a suspected criminal, immune cells in the brain take a two-tier approach to fighting off a threat, new research from the University of Michigan Health System finds.

For the first time, the scientists managed to capture that reaction in action, showing how certain immune cells locked onto a model of virus-infected brain cells, while also sending signals to neighboring uninfected cells to let them know about the immune attack.

BOSTON – A national rise in public bike sharing programs could mean less air pollution and more exercise, an environmental and health win-win for people in the cities that host them, but according to researchers at Beth Israel Deaconess Medical Center, more than 80 percent of bike share riders are putting themselves at significant health risk by not wearing helmets.

Los Angeles (April 30, 2012) —College students wishing to eat healthier may want to invest in a clear fruit bowl says a recent article published in Environment and Behavior (published by SAGE). The new study found that when fruits and vegetables are within arm's reach, students are more likely to eat them. Furthermore, making fruit and vegetables more visible increases the intake of fruit, but the same does not hold true for vegetables.

University of Iowa biologists have advanced the knowledge of human neurodevelopmental disorders by finding that a lack of a particular group of cell adhesion molecules in the cerebral cortex -- the outermost layer of the brain where language, thought and other higher functions take place -- disrupts the formation of neural circuitry.

ROCHESTER, Minn. -- Researchers studying multiple sclerosis(MS) have long been looking for the specific molecules in the body that cause lesions in myelin, the fatty, insulating cells that sheathe the nerves. Nearly a decade ago, a group at Mayo Clinic found a new enzyme, called Kallikrein 6, that is present in abundance in MS lesions and blood samples and is associated with inflammation and demyelination in other neurodegenerative diseases.

COLUMBUS, Ohio – Just 20 minutes of playing a violent shooting video game made players more accurate when firing a realistic gun at a mannequin – and more likely to aim for and hit the head, a new study found.

Players who used a pistol-shaped controller in a shooting video game with human targets had 99 percent more completed head shots to the mannequin than did participants who played other video games, as well as 33 percent more shots that hit other parts of the body.

Theoretical physicist Ali Naji from the IPM in Tehran and the University of Cambridge, UK, and his colleagues have shown how small random patches of disordered, frozen electric charges can make a difference when they are scattered on surfaces that are overall neutral. These charges induce a twisting force that is strong enough to be felt as far as nanometers or even micrometers away. These results, about to be published in EPJ E (1), could help to understand phenomena that occurr on surfaces such as those of large biological molecules.

SAN FRANCISCO, CA—April 29, 2012—Scientists at the Gladstone Institutes have determined how specific circuitry in the brain controls not only body movement but also motivation and learning, providing new insight into neurodegenerative disorders such as Parkinson's disease—and psychiatric disorders such as addiction and depression.

KOREA (30 April 2012) — There is more going on in DPR Korea than rocket science: local people in collaboration with natural resources scientists are taking control of their food supply through agroforestry. This is according to a report published in Agroforestry Systems journal.

How participatory agroforestry restored land and secured the food supply

Tablet based conference mirroring is giving residents an up close and personal look at images and making radiology case conferences a more interactive learning experience, a new study shows.

Residents at Northwestern University in Chicago are using tablets and a free screen sharing software during case conferences to see and manipulate the images that are being presented.