Brain

MAYWOOD, Il. -- A "brain pacemaker" called deep brain stimulation (DBS) remains an effective treatment for Parkinson's disease for at least three years, according to a study in the June 2012 online issue of Neurology®, the medical journal of the American Academy of Neurology.

But while improvements in motor function remained stable, there were gradual declines in health-related quality of life and cognitive abilities.

(Boston) – Researchers from Boston University School of Medicine (BUSM) have demonstrated in experimental models that blocking the Sigma-1 receptor, a cellular protein, reduced binge eating and caused binge eaters to eat more slowly. The research, which is published online in Neuropsychopharmacology, was led by Pietro Cottone, PhD, and Valentina Sabino, PhD, both assistant professors in the pharmacology and psychiatry departments at BUSM.

Most of us assume that confidence and certainty are preferred over uncertainty and bewilderment when it comes to learning complex information. But a new study led by Sidney D'Mello of the University of Notre Dame shows that confusion when learning can be beneficial if it is properly induced, effectively regulated, and ultimately resolved.

The study will be published in a forthcoming issue of Learning and Instruction.

COLUMBUS, Ohio – New research shows that omega-3 fatty acid supplements can lower inflammation in healthy, but overweight, middle-aged and older adults, suggesting that regular use of these supplements could help protect against and treat certain illnesses.

Neurons come in an astounding assortment of shapes and sizes, forming a thick inter-connected jungle of cells. Now, UCL neuroscientists have found that there is a simple pattern that describes the tree-like shape of all neurons.

Neurons look remarkably like trees, and connect to other cells with many branches that effectively act like wires in an electrical circuit, carrying impulses that represent sensation, emotion, thought and action.

A new gene-silencing strategy can reverse core symptoms associated with Huntington's disease, according to a preclinical study published by Cell Press in the June 21st issue of the journal Neuron. The short-term therapy produced sustained benefits in both mouse and primate animal models of this neurodegenerative disorder, which currently lacks an effective treatment.

"Our approach is feasible for development now into a therapy for Huntington's disease in man," says senior study author Don Cleveland of the University of California at San Diego.

Researchers at the RIKEN Brain Science Institute (BSI) in Japan have uncovered two brain signals in the human prefrontal cortex involved in how humans predict the decisions of other people. Their results suggest that the two signals, each located in distinct prefrontal circuits, strike a balance between expected and observed rewards and choices, enabling humans to predict the actions of people with different values than their own.

The human brain can recognize thousands of different objects, but neuroscientists have long grappled with how the brain organizes object representation; in other words, how the brain perceives and identifies different objects. Now researchers at the MIT Computer Science and Artificial Intelligence Lab (CSAIL) and the MIT Department of Brain and Cognitive Sciences have discovered that the brain organizes objects based on their physical size, with a specific region of the brain reserved for recognizing large objects and another reserved for small objects.

The throat and facial movements that twist the air pushing through your vocal cords into words could be rooted in the well-meaning expressions primates exchange with each other, according to two recent studies based at Princeton University.

Amsterdam, NL, June 20, 2012 – Some Parkinson's patients report that their motor function is better upon awakening in the morning, which is contrary to what would be expected after a night without medication. This phenomenon, known as sleep benefit, has been studied but no consistent variables have been found and in the last decade there has been little new research.

Pathological rage can be blocked in mice, researchers have found, suggesting potential new treatments for severe aggression, a widespread trait characterized by sudden violence, explosive outbursts and hostile overreactions to stress.

Montreal, June 20, 2012 – Thanks to modern science, we know that love lives in the brain, not in the heart. But where in the brain is it – and is it in the same place as sexual desire? A recent international study is the first to draw an exact map of these intimately linked feelings.

The impact of traumatic injuries to the brain – whether sustained in combat or on the playing fields of America's schools – is a major topic for international migraine specialists the week of June 18 as they gather in Los Angeles for the 54th Annual Scientific Sessions of the American Headache Society. This is among many timely issues concerning headache, migraine, and brain injuries on the four-day agenda here which runs through Sunday morning, June 24.

This is the first suggestion of a heritable abnormality in otherwise healthy humans, and this has important implications for our understanding of the genetic basis of cognition.

Dr Josie Briscoe of Bristol's School of Experimental Psychology and colleagues at the Institute of Child Health in London studied eight members of a single family (aged 8 years), who despite all having high levels of intelligence have since childhood, experienced profound difficulties in recalling sentences and prose, and language difficulties in listening comprehension and naming less common objects .

A group of Spanish researchers has discovered a new function of the neurotransmitter dopamine in controlling sleep regulation. Dopamine acts in the pineal gland, which is central to dictating the 'circadian rhythm' in humans—the series of biological processes that enables brain activity to adapt to the time of the day (that is, light and dark cycles).