LOS ANGELES (Aug. 14, 2012) – An experimental immune-based therapy more than doubled median survival of patients diagnosed with the most aggressive malignant brain tumor, Cedars-Sinai Medical Center researchers reported in Cancer Immunology, Immunotherapy, published online Aug. 3.
Brain
Long-term methadone treatment can cause changes in the brain, according to recent studies from the Norwegian Institute of Public Health. The results show that treatment may affect the nerve cells in the brain. The studies follow on from previous studies where methadone was seen to affect cognitive functioning, such as learning and memory.
Sticky plaques of proteins called amyloids mark several different, though related degenerative brain diseases including Alzheimer's, Parkinson's and Creutzfeld-Jacobs.The symptoms of these disorders overlap and methods to diagnose and monitor them are not very advanced.
Current drug therapy for patients with HIV is unable to control the complete replication of the virus in the brain. The drugs therefore do not have any effect against the complications associated with neurocognitive impairment in patients with HIV. New research by Joseph Steiner and colleagues from Johns Hopkins University has discovered that a group of plant polyphenols known as catechins, which naturally occur in green tea and the seed of the cacao tree, may help in the prevention of these neurological complications.
eople spend their last years alone. Spouses pass and children scatter. But being lonely is much more than a silent house and a lack of companionship. Over time, loneliness not only takes a toll on the psyche but can have a serious physical impact as well.
Feeling lonely has been linked to an increased risk of heart disease, Alzheimer's disease, depression and even premature death. Developing effective treatments to reduce loneliness in older adults is essential, but previous treatment efforts have had limited success.
s at Weill Cornell Medical College have deciphered a mouse's retina's neural code and coupled this information to a novel prosthetic device to restore sight to blind mice. The researchers say they have also cracked the code for a monkey retina — which is essentially identical to that of a human —and hope to quickly design and test a device that blind humans can use.
How the intricate network of blood vessels forms within the brain has long fascinated biologists. Though the human brain comprises only 2 percent of body weight it receives up to 15 percent of the cardiac output through this network, or vessel vasculature. The vasculature in the human brain consists of a complex branching network of blood vessels, in total some several hundred miles in length.
In a major breakthrough, an international team of scientists has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief. The team from the University of Adelaide and University of Colorado has discovered the key mechanism in the body's immune system that amplifies addiction to opioid drugs.
Laboratory studies have shown that the drug (+)-naloxone (pronounced: PLUS nal-OX-own) will selectively block the immune-addiction response.
Connecting the dots between two molecules whose levels are decreased in depression and increased by current antidepressants could yield new therapies, researchers say.
Girls with attention deficit hyperactivity disorder are significantly more likely to attempt suicide or injure themselves as young adults than girls who do not have ADHD, according to research published by the American Psychological Association.
Positive encouragement and constructive criticism could be wasting their breath according to the latest research from a psychology expert at Queen Mary, University of London.
The study, published in Frontiers in Neuroscience, found that when people received either positive or negative feedback about their performance on complex decision-making tasks, it made their decision making worse.
Although clearly discernible in the embryo, shortly afterwards it fuses with other bones beyond recognition. Consequently, researchers have often missed it. Now, however, paleontologists from the University of Zurich have rediscovered it: the "os interparietale," a skull bone also referred to as the interparietal. Using imaging methods, they were able to detect its presence in all mammals -- including humans, which is new as it was previously believed to have been lost in the course of evolution.
Eating cocoa flavanols daily may improve mild cognitive impairment, according to new research in the American Heart Association's journal Hypertension.
Each year, more than six percent of people aged 70 years or older develop mild cognitive impairment, a condition involving memory loss that can progress to dementia and Alzheimer's disease.
MADISON -- When conflict breaks out in social groups, individuals make strategic decisions about how to behave based on their understanding of alliances and feuds in the group.
But it's been challenging to quantify the underlying trends that dictate how individuals make predictions, given they may only have seen a small number of fights or have limited memory.
—A team at Children's National Medical Center has found that external stimulation has an impact on the postnatal development of a specific region of the brain. Published in Nature Neuroscience, the study used sensory deprivation to look at the growth and collection of NG2-expressing oligodendrocyte progenitor cells (NG2 cells) in the sensory cortex of the brain. This type of research is part of the Center for Neuroscience Research focus on understanding the development and treatment of white matter diseases.