Brain

WEST LAFAYETTE, Ind. - A new tool that could allow for faster, more comprehensive testing of brain tissue during surgery successfully identified the cancer type, grade and tumor margins in five brain surgery patients, according to a Purdue University and Brigham and Women's Hospital study.

The tool sprays a microscopic stream of charged solvent onto the tissue surface to gather information about its molecular makeup and produces a color-coded image that reveals the nature and concentration of tumor cells.

Research at the University of Edinburgh tracked electrical signals in the part of the brain linked to spatial awareness.

The study could help us understand how, if we know a room, we can go into it with our eyes shut and find our way around. This is closely related to the way we map out how to get from one place to another

Scientists found that brain cells, which code location through increases in electrical activity, do not do so by talking directly to each other. Instead, they can only send each other signals through cells that are known to reduce electrical activity.

MAYWOOD, Il. - Among the most feared and devastating strokes are ones caused by blockages in the brain's critical basilar artery system. When not fatal, basilar artery strokes can cause devastating deficits, including head-to-toe paralysis called "locked-in syndrome."

Philadelphia, PA, January 10, 2013 – Horrific images from One Flew Over the Cuckoo's Nest notwithstanding, modern electroconvulsive therapy (ECT) remains one of the safest and most effective antidepressant treatments, particularly for patients who do not tolerate antidepressant medications or depression symptoms that have failed to respond to antidepressant medications.

SAN DIEGO – Apparent stem cell transplant success in mice may hold promise for people with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease. The results of the study were released today and will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013.

WASHINGTON — Scientists have long wondered how nerve cell activity in the brain's hippocampus, the epicenter for learning and memory, is controlled — too much synaptic communication between neurons can trigger a seizure, and too little impairs information processing, promoting neurodegeneration. Researchers at Georgetown University Medical Center say they now have an answer.

WINSTON-SALEM, N.C. – Jan. 9, 2013 – New research from Wake Forest Baptist Medical Center shows that patients suffering from aggressive brain tumors can be effectively treated with smaller radiation fields to spare the rest of the brain and preserve cognition.

AUGUSTA, Ga. – As we age, it just may be the ability to filter and eliminate old information – rather than take in the new stuff - that makes it harder to learn, scientists report.

"When you are young, your brain is able to strengthen certain connections and weaken certain connections to make new memories," said Dr. Joe Z. Tsien, neuroscientist at the Medical College of Georgia at Georgia Regents University and Co-Director of the GRU Brain & Behavior Discovery Institute.

The channel protein Pannexin1 keeps nerve cells flexible and thus the brain receptive for new knowledge. Together with colleagues from Canada and the U.S., researchers at the Ruhr-Universität Bochum led by the junior professor Dr. Nora Prochnow from the Department of Molecular Brain Research describe these results in PLoS ONE. In the study, mice comprising no Pannexin1 in memory-related brain structures displayed symptoms similar to autism. Their nerve cells lacked synaptic plasticity, i.e.

DURHAM, N.C. -- Two years of painstaking observation on the social interactions of a troop of free-ranging monkeys and an analysis of their family trees has found signs of natural selection affecting the behavior of the descendants.

Rhesus macaques who had large, strong networks tended to be descendants of similarly social macaques, according to a Duke University team of researchers. And their ability to recognize relationships and play nice with others also won them more reproductive success.

Older adults who have suffered from aphasia for a long time can nevertheless improve their language function and maintain these improvements in the long term, according to a study by Dr. Ana Inés Ansaldo, PhD, a researcher at the Research Centre of the Institut universitaire de gériatrie de Montréal (University Geriatrics Institute of Montreal) and a professor in the School of Speech-Language Pathology and Audiology at the Faculty of Medicine of Université de Montréal. The study was published in Brain and Language.

Washington, DC — Seniors who have spoken two languages since childhood are faster than single-language speakers at switching from one task to another, according to a study published in the January 9 issue of The Journal of Neuroscience. Compared to their monolingual peers, lifelong bilinguals also show different patterns of brain activity when making the switch, the study found.

COLUMBUS, Ohio – An experimental oral drug given to mice after a spinal cord injury was effective at improving limb movement after the injury, a new study shows.

The compound efficiently crossed the blood-brain barrier, did not increase pain and showed no toxic effects to the animals.

(Santa Barbara, Calif.) –– For decades, consensus among psychologists has held that a group of five personality traits –– or slight variations of these five –– are a universal feature of human psychology. However, a study by anthropologists at UC Santa Barbara raises doubt about the veracity of that five-factor model (FFM) of personality structure as it relates to indigenous populations. Their findings appear in the current issue of the American Psychological Association's Journal of Personality and Social Psychology.

January 8, 2013 – A multinational team of researchers made a significant step forward in trying to understand how birds produce their beautiful songs. "We used cutting-edge 3D imaging techniques to understand the complicated structure of the vocal organ of songbirds, the syrinx", says Dr. Coen Elemans, from the University of Southern Denmark, the senior author on the study. Elemans and his colleagues are publishing their findings January 8, 2013 in BioMed Central's open access journal BMC Biology.