Brain

Luxembourg, 6 May 2013 – Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have discovered that immune cells in the brain can produce a substance that prevents bacterial growth: namely itaconic acid. Until now, biologists had assumed that only certain fungi produced itaconic acid. A team working with Dr. Karsten Hiller, head of the Metabolomics Group at LCSB, and Dr. Alessandro Michelucci has now shown that even so-called microglial cells in mammals are also capable of producing this acid. "This is a ground breaking result," says Prof. Dr.

Washington D.C., May 6, 2013 – A study published in the May 2013 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that mental health resources provided by schools are significantly associated with whether adolescents with mental disorders receive needed mental health services. In particular, adolescents with disorders attending schools that engage in early identification of emotional problems, are significantly more likely to receive mental health services.

WASHINGTON, DC – Chemicals called polybrominated diphenyl ethers (PBDEs) have been used for decades to reduce fires in everyday products such as baby strollers, carpeting and electronics. A new study to be presented on Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting shows that prenatal exposure to the flame retardants is associated with lower intelligence and hyperactivity in early childhood.

More than two million people in the United States suffer from epilepsies, a group of neurological disorders caused by abnormal nerve cell firing in the brain which often produce debilitating seizures. Although anti-epileptic drugs and other therapies reduce seizures in about two-thirds of patients, the remaining one-third do not respond to any form of therapy and those who take drugs can experience harmful side effects.

UCSF scientists controlled seizures in epileptic mice with a one-time transplantation of medial ganglionic eminence (MGE) cells, which inhibit signaling in overactive nerve circuits, into the hippocampus, a brain region associated with seizures, as well as with learning and memory. Other researchers had previously used different cell types in rodent cell transplantation experiments and failed to stop seizures.

In a randomized trial performed to help resolve the uncertainty about the optimal oxygen saturation therapy in extremely preterm infants, researchers found that targeting saturations of 85 percent to 89 percent compared with 91 percent to 95 percent had no significant effect on the rate of death or disability at 18 months, according to a study published by JAMA. The study is being released early online to coincide with its presentation at the Pediatric Academic Societies annual meeting.

WASHINGTON, DC – More children today have a disability than a decade ago, and the greatest increase is among kids in higher-income families, according to a study to be presented Sunday, May 5, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC.

The study also found that disabilities related to physical health conditions have decreased, while disabilities due to neurodevelopmental and mental health problems have increased greatly.

WASHINGTON, DC – Pediatricians, economists, social scientists and policy experts will come together on Saturday, May 4, to address one of the greatest threats to child health — poverty.

The group will take part in a plenary session titled, "A National Agenda to End Childhood Poverty," at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC. The session will cover a range of issues related to childhood poverty, including its measurement, its impact on child health and potential solutions.

We all know that buying food when we are hungry is a recipe for disaster. When we are hungry, we can be especially sensitive to sights and smells of foods that will satiate, but may lack in nutrient content. What if we could make our meal choices when we are full, and not anticipating the feeling of satiation we all enjoy? Would we make healthier choices? Researchers at the Cornell Center for Behavioral Economics in Child Nutrition Programs (B.E.N. Center) set out to test whether or not preordering lunch would nudge students make healthier entrée choices.

The baboons' choices, conclude the authors, clearly relied on this latter "more than" or "less than" cognitive approach, known as the analog system. The baboons were able to consistently discriminate pairs with numbers larger than three as long as the relative difference between the peanuts in each cup was large. Research has shown that children who have not yet learned to count also depend on such comparisons to discriminate between number groups, as do human adults when they are required to quickly estimate quantity.

Mathematicians from Queen Mary, University of London will bring researchers one-step closer to understanding how the structure of the brain relates to its function in two recently published studies.

Publishing in Physical Review Letters the researchers from the Complex Networks group at Queen Mary's School of Mathematics describe how different areas in the brain can have an association despite a lack of direct interaction.

PITTSBURGH—It's no secret that stress increases your susceptibility to health problems, and it also impacts your ability to solve problems and be creative. But methods to prevent associated risks and effects have been less clear – until now.

ANN ARBOR, Mich. - The U.S. Food and Drug Administration's warning that high doses of the antidepressant citalopram can cause potentially serious abnormal heart rhythms might be doing more harm than good.

In 2011, the FDA attached a warning to the drug, also known as Celexa, based on data linking higher doses of the drug to potentially fatal abnormal changes in the electrical activity of the heart.

Leaving the house in the morning may seem simple, but with every move we make, our brains are working feverishly to create maps of the outside world that allow us to navigate and to remember where we are.

Take one step out the front door, and an individual brain cell fires. Pass by your rose bush on the way to the car, another specific neuron fires. And so it goes. Ultimately, the brain constructs its own pinpoint geographical chart that is far more precise than anything you'd find on Google Maps.

Brain function in adults as young as 35 may decline as their heart disease risk factors increase, according to new research in the American Heart Association journal Stroke.

"Young adults may think the consequences of smoking or being overweight are years down the road, but they aren't," said Hanneke Joosten, M.D., lead author and nephrology fellow at the University Medical Center in Groningen, The Netherlands.