Irritable bowel syndrome patients extensively suffer from chronic visceral hypersensitivity, with involvement of all levels of the brain-gut axis, as well as various neurotransmitters. Chronic visceral hypersensitivity can occur in the periphery, spinal cord and central nervous system, which has been shown to be the main pathophysiological mechanism underlying abdominal pain in patients with irritable bowel syndrome. Acupuncture at Tianshu (ST25) and Shangjuxu (ST37) has been reported to relieve visceral hypersensitivity for irritable bowel syndrome.
Brain
The population of northeastern China has a high incidence of ischemic stroke. Previous studies have shown that intracranial large-artery atherosclerosis is one of the main causes of ischemic stroke, and that the mechanisms are related to inflammation and thrombosis of the affected arteries.
Astragaloside IV, the main component of the traditional Chinese medicine astragalus membra-naceus, has been shown to inhibit inflammation, oxidation, and apoptosis, and exerts immu-noregulatory effects. Xiaohong Zhang and colleagues from School of Pharmacutical Sciences, Jilin University investigated whether astragaloside IV could promote the repair of injured sciatic nerve. Denervated sciatic nerve of mice was subjected to anastomosis. The mice were intraperitoneally injected with 10, 5, 2.5 mg/kg astragaloside IV per day for 8 consecutive days.
The science behind the tingling sensation caused by eating a popular Asian spice has been explained by researchers at UCL.
The study, which is published in the journal Proceedings of the Royal Society B, helps shed light on the complex interactions between the senses of taste and touch, and could lead to a greater understanding of the causes of the tingling sensations experienced by many chronic pain patients.
Neuroscientists at Western University (London, Canada) have made a remarkable new discovery revealing the underlying molecular process by which opiate addiction develops in the brain. Opiate addiction is largely controlled by the formation of powerful reward memories that link the pleasurable effects of opiate-class drugs to environmental triggers that induce drug craving in individuals addicted to opiates. The research is published in the September 11th issue of The Journal of Neuroscience.
Camouflaged creatures can perform remarkable disappearing acts but new research shows that predators can learn to read camouflage. The study, which used human subjects as predators searching for hidden moths in computer games, found that the subjects could learn to find some types of camouflaged prey faster than others.
The search for the cause of multiple sclerosis, a debilitating disease that affects up to a half million people in the United States, has confounded researchers and medical professionals for generations. But Steven Schutzer, a physician and scientist at Rutgers New Jersey Medical School, has now found an important clue why progress has been slow – it appears that most research on the origins of MS has focused on the wrong part of the brain.
Heart disease patients with positive attitudes are more likely to exercise and live longer, according to new research in the American Heart Association journal Circulation: Cardiovascular Quality and Outcomes.
Researchers used a questionnaire to assess the moods of 600 ischemic heart disease patients in a Denmark hospital. Five years later, researchers found:
Cost, fear and a lack of information are barriers for minorities in urban communities to learn and perform CPR, according to new research in the American Heart Association journal Circulation: Cardiovascular Quality and Outcomes.
Move over, plaques and tangles.
Researchers at Emory University School of Medicine's Alzheimer's Disease Research Center have identified a previously unrecognized type of pathology in the brains of patients with Alzheimer's disease.
These tangle-like structures appear at early stages of Alzheimer's and are not found in other neurodegenerative diseases such as Parkinson's disease.
Irvine, Calif., Sept. 10, 2013 — By studying how memories are made, UC Irvine neurobiologists created new, specific memories by direct manipulation of the brain, which could prove key to understanding and potentially resolving learning and memory disorders.
JUPITER, FL, September 10, 2013 – The human brain is exquisitely adept at linking seemingly random details into a cohesive memory that can trigger myriad associations—some good, some not so good. For recovering addicts and individuals suffering from post-traumatic stress disorder (PTSD), unwanted memories can be devastating. Former meth addicts, for instance, report intense drug cravings triggered by associations with cigarettes, money, even gum (used to relieve dry mouth), pushing them back into the addiction they so desperately want to leave.
Bilingual speakers can switch languages seamlessly, likely developing a higher level of mental flexibility than monolinguals, according to Penn State linguistic researchers.
"In the past, bilinguals were looked down upon," said Judith F. Kroll, Distinguished Professor of Psychology, Linguistics and Women's Studies. "Not only is bilingualism not bad for you, it may be really good. When you're switching languages all the time it strengthens your mental muscle and your executive function becomes enhanced."
EAST LANSING, Mich. — Bilingual education programs have a substantial spillover effect on the students they're not designed for, according to a groundbreaking study co-authored by a Michigan State University scholar.
Texas elementary students who speak English as their home language and were enrolled in schools with bilingual education programs performed much better on state math and reading tests than native English-speaking students at schools without bilingual education programs.
Compared to younger adults, older people are less adept at reading emotion in their spouse's face. But when their spouse isn't present, older and younger adults are equally able to discern their significant others' moods.
These findings, published in Psychological Science, a journal of the Association for Psychological Science, suggest that older adults retain the ability to make accurate judgments about others emotions using their acquired knowledge, but not sensory cues.