Brain

DURHAM, N.C. -- When marine biologist Eleanor Caves of the University of Exeter thinks back to her first scuba dives, one of the first things she recalls noticing is that colors seem off underwater. The vivid reds, oranges, purples and yellows she was used to seeing in the sunlit waters near the surface look increasingly dim and drab with depth, and before long the whole ocean loses most of its rainbow leaving nothing but shades of blue.

Much of common pharmaceutical development today is the product of laborious cycles of tweaking and optimization. In each drug, a carefully concocted formula of natural and synthetic enzymes and ingredients works together to catalyze a desired reaction. But in early development, much of the process is spent determining what quantities of each enzyme to use to ensure a reaction occurs at a specific speed.

Coral reefs around the world are under threat from rising sea temperatures, ocean acidification, disease and overfishing, among other reasons.

Tracking signs of stress and ill health is difficult because corals -- an animal host coexisting with algae, bacteria, viruses and fungi -- are dynamic organisms that behave differently depending on what's happening in their environment. Some scientists wonder if recording changes in coral movements over time could help with monitoring a coral reef's health.

Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation--at least when all is functioning normally.

Volcanic eruptions deep in our oceans are capable of extremely powerful releases of energy, at a rate high enough to power the whole of the United States, according to research published today.

Eruptions from deep-sea volcanoes were long-thought to be relatively uninteresting compared with those on land. While terrestrial volcanoes often produce spectacular eruptions, dispersing volcanic ash into the environment, it was thought that deep marine eruptions only produced slow moving lava flows.

New FLEET research confirms the potential for topological materials to substantially reduce the energy consumed by computing.

The collaboration of FLEET researchers from University of Wollongong, Monash University and UNSW have shown in a theoretical study that using topological insulators rather than conventional semiconductors to make transistors could reduce the gate voltage by half, and the energy used by each transistor by a factor of four.

Researchers at Beam Therapeutics have developed a redesigned base editor that shows considerable promise in directly repairing the single-base mutation that causes sickle-cell disease (SCD). Many strategies are being pursued to harness genome editing approaches including CRISPR to treat patients with SCD and related hemoglobinopathies. The most advanced method in the clinic involves targeting an upstream regulatory pathway to switch on expression of the fetal hemoglobin gene but does not target the SCD mutation directly.

If the CO2 content of the atmosphere is not to increase any further, carbon dioxide must be converted into something else. However, as CO2 is a very stable molecule, this can only be done with the help of special catalysts. The main problem with such catalysts has so far been their lack of stability: after a certain time, many materials lose their catalytic properties.

Solid-matrix catalysts called heterogeneous catalysts are among the most widespread industrial applications in reducing toxic gases, unburned fuel, and particulate matter in the exhaust stream from the combustion chamber. They are also used in energy, chemical, and pharmaceutical sectors, i.e., production of biodiesel, polymers, biomass/waste conversion into valuable products, and many others processes. All thanks to their active sites and high surface.

Researchers at SAHMRI and Flinders University have conducted the largest ever meta-analysis of wellbeing studies from around the world to answer the question, 'What's the best way to build personal wellbeing?'.

The analysis included 400+ clinical trials involving more than 50,000 participants. Researchers divided people into three main groups, those in generally good health, those with physical illness and those with mental illness.

Videoconferences may be less exhausting if participants feel some sense of group belonging, according to new research published by the American Psychological Association.

The internet seems like the place to go to get into fights. Whether they're with a family member or a complete stranger, these arguments have the potential to destroy important relationships and consume a lot of emotional energy.

Southeastern Tibet is one of the most glaciated regions on the Tibetan Plateau both at present and during the Quaternary. Numerical dating of glacial deposits has allowed the establishment of a provisional chronology of Quaternary glacial fluctuations in this region, with the oldest glaciation (Guxiang Glaciation) occurring in marine oxygen isotope stage 6 (MIS-6).

Scientists have sequenced ancient DNA from soil for the first time and the advance will transform what is known about everything from evolution to climate change.

The findings have been described as the 'moon landings' of genomics because researchers will no longer have to rely on finding and testing fossils to determine genetic ancestry, links and discoveries - and it is thanks to Stone Age black bears who defecated in a remote cave in Mexico 16,000 years ago.

More blood thinners aren't automatically better, another study confirms.

A new publication in JAMA Internal Medicine focuses on the minimal pros and the concerning cons of combining a daily aspirin with a drug from the newer class of anticoagulants that include apixaban, dabigatran, edoxaban and rivaroxaban.