Brain

Students overall performed better – and educationally disadvantaged students generally made even greater strides than everyone else – in an introductory biology course at a university where recent budget woes doubled class sizes for the course, cut lab times and reduced the number of graduate teaching assistants.

A paper published online today in Science provides evidence that the Methyl-CpG-Binding Protein 2 (MeCP2) is required throughout life to maintain healthy brain function. The findings are reported from the Baylor College of Medicine lab of Huda Zoghbi, HHMI investigator and Director of the Jan and Dan Duncan Neurological Research Institute.

Mutations in MeCP2 cause the autism spectrum disorder Rett Syndrome, and have been seen in some cases of classic autism, childhood schizophrenia and milder neuropsychiatric conditions such as anxiety and learning disabilities.

When people are depressed or anxious, they are much more likely to see their glass as half empty than half full. In tough times, evidence of that same pessimistic outlook can be seen in dogs, rats, and birds. Now, researchers reporting online on June 2 in Current Biology, a Cell Press publication, show that bees, too, share those very same hallmarks of negative emotion.

SAN FRANCISCO, CA—June 2, 2011—Scientists at the Gladstone Institutes have identified a drug candidate that diminishes the effects of both Alzheimer's disease and Huntington's disease in animal models, offering new hope for patients who currently lack any medications to halt the progression of these two debilitating illnesses.

A study in a special early online publication of Cell, a Cell Press publication, reveals a promising new slow-release compound that protects mice against the neurodegenerative effects of both Huntington's and Alzheimer's disease. The 'prodrug' known only as JM6 works through a pathway involved in the breakdown of the amino acid tryptophan.

Surprisingly, JM6 delivers those benefits even though it doesn't cross the blood-brain barrier and therefore cannot act directly on the brain.

Psychology researchers at the University of Alberta have found an interesting wrinkle in the decision- making process people use when gambling: People confronted with risky choices respond differently when they rely on past experiences, rather than when they just focus on the odds of winning or losing.

What links speed, power, and the color red? Hint: it's not a sports car.

It's your muscles.

A new study, published in the latest issue of the journal Emotion, finds that when humans see red, their reactions become both faster and more forceful. And people are unaware of the color's intensifying effect.

The findings may have applications for sporting and other activities in which a brief burst of strength and speed is needed, such as weightlifting. But the authors caution that the color energy boost is likely short-lived.

From a distance, Callie (not her real name) appears to be a normal if quiet 5-year-old girl. But when faced with a toy that blows large soap bubbles—an activity that makes the vast majority of kindergarteners squeal and leap with delight—she is uninterested in popping the bubbles or taking a turn with the gun herself. When offered dolls or other toys, she is equally unmoved. When groups of children congregate to play, Callie does not join them. Even at home, she is quiet and withdrawn.

When we've got a problem to solve, we don't just use our brains but the rest of our bodies, too. The connection, as neurologists know, is not uni-directional. Now there's evidence from cognitive psychology of the same fact. "Being able to use your body in problem solving alters the way you solve the problems," says University of Wisconsin psychology professor Martha Alibali. "Body movements are one of the resources we bring to cognitive processes."

Just before 10:00 a.m. on June 20, 2001, a uniformed police officer was dispatched to do what he thought was a routine welfare check at a home in Houston, Texas. When the officer met Andrea Yates at the door, she immediately told him, "I just killed my kids." When Yates was later asked why she drowned her five children, she claimed she had to in order to save them from hell. The police would learn that Yates had been suffering from long-term post-partum depression and psychosis.

Brain cancer therapy may be more effective if the expression of an iron-storing protein is decreased to enhance the action of therapeutic drugs on brain cancer cells, according to Penn State College of Medicine researchers.

and Spanish.

A gesture as simple as allowing children to freely choose the vegetables they want to eat helps to increase the consumption of these foods in children, as University of Granada has found. Moreover, his work suggests that the bitter taste of calcium, present in vegetables such as spinach, collard greens, cabbage, onions, chard or broccoli, can be a factor negatively influencing children's consumption of vegetables.

EVANSTON, Ill. --- Do those lightening fast disclaimers at the end of radio and television advertisements scare you away or simply seem like white noise required by regulatory agencies?

According to Northwestern University and Wake Forest University research now online in the Journal of Consumer Research, fast disclaimers can give consumers the impression that an advertiser is trying to conceal information. However, trusted brands (versus trust-unknown or not-trusted brands) are immune to the adverse effects of fast disclaimers.

Tiny electrodes have been coated with a drug-loaded polymer in an attempt to design an implant capable of detecting a number of neurological symptoms, such as those associated with an epileptic seizure, and treating them simultaneously.

In a study published today, 2 June 2011, in IOP Publishing's Journal of Neural Engineering, researchers have developed a novel technology to precisely modulate individual neurons in rats, allowing the molecular, neuronal, and circuit functions to be analysed with unprecedented precision.